- Corneal surgery and disorders
- Intraocular Surgery and Lenses
- Glaucoma and retinal disorders
- Corneal Surgery and Treatments
- Ophthalmology and Visual Impairment Studies
- Ocular Infections and Treatments
- Ocular Surface and Contact Lens
- Retinal and Macular Surgery
- Retinal Diseases and Treatments
- Asthma and respiratory diseases
- Ocular and Laser Science Research
- Inhalation and Respiratory Drug Delivery
- Ocular Diseases and Behçet’s Syndrome
- Traumatic Ocular and Foreign Body Injuries
- HER2/EGFR in Cancer Research
- Retinal and Optic Conditions
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cerebral Venous Sinus Thrombosis
- Chronic Myeloid Leukemia Treatments
- Adaptive optics and wavefront sensing
- Pharmacogenetics and Drug Metabolism
- Eicosanoids and Hypertension Pharmacology
- Advanced optical system design
- Tactile and Sensory Interactions
- Facial Rejuvenation and Surgery Techniques
Harvard University
1997-2021
Massachusetts Eye and Ear Infirmary
1993-2021
Georgetown University
2015-2018
Johnson & Johnson (United States)
2018
Woolfson Eye Institute
2018
MedStar Washington Hospital Center
2015
University of Minnesota
2015
Boston Sports & Shoulder Center
2013-2015
Rush University Medical Center
2015
Minnesota Eye Consultants
2011-2015
To evaluate a femtosecond laser system to create the capsulotomy.Porcine and cadaver eye studies were performed at OptiMedica Corp., Santa Clara, California, USA; human trial was Centro Laser, Santo Domingo, Dominican Republic.Experimental clinical study.Capsulotomies by an optical coherence tomography-guided evaluated in porcine eyes. Subsequently, procedure 39 patients as part of prospective randomized study laser-assisted cataract surgery. The accuracy capsulotomy size, shape, centration...
An image-guided, femtosecond laser can create precisely placed, accurate cuts in the eye to improve cataract surgery.
A 193-nm excimer laser system was used to create deep stromal ablations in seven New Zealand white rabbits and shallow three. Eyes were randomized for treatment with topical mitomycin C, steroids, erythromycin; steroids or erythromycin only. All regimens instituted twice daily 14 days. eyes reepithelialized normally within 3 5 During 10 weeks of follow-up, all developed moderate reticular subepithelial haze without significant differences among groups. Results light, fluorescence, electron...
To compare 2 optical patient interface designs used for femtosecond laser-assisted cataract surgery.Optimedica Corp., Santa Clara, California, USA, and Centro Laser, Santo Domingo, Dominican Republic.Experimental clinical studies.Laser capsulotomy was performed during surgery with a curved contact lens (CCL) or liquid immersion (LOI). The presence of corneal folds, incomplete capsulotomy, subconjunctival hemorrhage, eye movement laser treatment were analyzed using video coherence tomography....
The patient-administered Health Assessment Questionnaire (HAQ) is widely used in rheumatology studies. Another health quality assessment technique commonly for other non-rheumatological conditions the 'Short Form 36' (SF36). This has questions designed to assess eight aspects of ranging from physical limitations general perceptions vitality and mental well-being. study presents information on status 137 patients with rheumatoid arthritis (RA) assessed by both SF36 HAQ. Summary statistics are...
To compare flap thickness reproducibility of the femtosecond laser and two mechanical microkeratomes.Flap for all eyes was measured as difference between preoperative (day surgery) full corneal post-flap creation central stromal bed using ultrasonic pachymetry. Flap values produced by three different microkeratome systems were compared accuracy reproducibility.For 99 flaps created IntraLase FS with an intended 110 microm, mean achieved 119 +/- 12 microm (range: 82 to 149 microm). In 100...
To assess the efficacy and safety of a sustained-release intracanalicular dexamethasone insert for treatment postoperative ocular inflammation pain in patients having cataract surgery.Twenty-one United States sites.Prospective multicenter randomized parallel-arm double-masked vehicle-controlled phase 3 study.Patients with planned clear corneal surgery were (1:1) to receive or placebo, was placed canaliculus eye immediately after (Day 1). The primary endpoints complete absence anterior...
To evaluate the efficacy of intracorneal ring segments to treat keratoconus and post-laser in situ keratomileusis (LASIK) keratectasia implanted by using either mechanical dissection or a femtosecond laser.Thirty-three eyes 29 patients had (17 eyes) laser (16 eyes). Mean follow-up was 10.3 months. Parameters assessed before after surgery included uncorrected visual acuity (UCVA), best spectacle-corrected (BSCVA), manifest refractive spherical equivalent (MRSE), cylinder (RC), contact...
PURPOSE: To determine the value of intraoperative aberrometry in cases toric intraocular lens (IOL) implantation and positioning. METHODS: In this non-randomized retrospective comparative trial, two groups eyes underwent cataract extraction with IOL implantation: group (n = 37 eyes), where power alignment were determined before surgery automated keratometry, standard optical biometry, an online calculator then refined using aberrometry, 27 selection was performed a similar manner but without...
Purpose To compare effective phacoemulsification time (EPT) for the removal of brunescent cataracts treated with femtosecond laser–assisted cataract surgery standard techniques. Setting Ruhr University Eye Hospital, Bochum, Germany. Design Comparative prospective case study. Methods The Lens Opacities Classification System III (LOCS III) grading system was used to measure eyes divided into 4 groups having surgery. Groups 1 and 2 contained LOCS grade nuclear opalescence (NO) 3 surgery,...
Purpose: The purpose of this study was to determine an arcuate incision (AI) nomogram treat astigmatism during femtosecond laser-assisted cataract surgery. Methods: This is a retrospective, cohort study. Femtosecond laser (FSL)-assisted transepithelial AIs were created at 9.0 mm optical zone, 80% depth, centered on the limbus. We modified manual Donnenfeld limbal relaxing 70% for with-the-rule (WTR), oblique (OBL), and 100% against-the-rule (ATR) astigmatism. correction index (CI) equaled...
We used Maddox double-rod measurements to determine if positionally induced ocular cyclotorsion occurs when a patient moves from the seated supine position. were determined twice while patients (N = 30) viewed fixation light at distance of 7 feet in both and positions. The difference between axis made positions was not statistically significant. There also no significant two These data show that eyes do undergo
Little information on the natural course of corneal astigmatism following cataract surgery exists. We report a prospective, computerized analysis postoperative astigmatism, based keratometry measurements, 137 cases extracapsular extraction with intraocular lens implantation performed by one surgeon. No sutures were cut postoperatively. Surgery induced 1.44 diopters (D) with-the-rule at month, which declined rate 0.77 D and 0.35 per month for next two months, respectively, more gradual...
Purpose: To compare 18% ethanol versus mechanical epithelial debridement in a group of patients having photorefractive keratectomy (PRK) for low to moderate myopia or astigmatism. Setting: Hospital San Jose de Monterrey, Mexico. Methods: This prospective, paired study comprised 18 who had bilateral PRK between June 1994 and March 1995. One eye (alcohol) the other, mechanical. Time PRKs was about 6 months. The two groups (alcohol mechanical) were compared rate re-epithelialization, refractive...
• Recent reports have suggested a role for BW-B759U in the treatment of cytomegalovirus retinitis. The present study presents ophthalmoscopic features three treated patients, and examines microscopic findings eyes first patient ever with BWB759U Ophthalmoscopic improvement on drug therapy included remission perivascular infiltration, stabilization extent retinal area involved, development pigmented chorioretinal scar involved area. Relapses occurred cessation therapy, repeated courses were...
The purpose of this study is to evaluate the patient experience sustained release dexamethasone intracanalicular insert (Dextenza™) following cataract surgery as part a Phase III clinical trial program.This cross-sectional, qualitative evaluation involved individual interviews lasting approximately 45 minutes. Patients from four US investigational sites who had previously received an were enrolled. There no predesignated end points; was survey seeking deeper understanding...