A5026845724- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Mechanical Circulatory Support Devices
- Hemodynamic Monitoring and Therapy
- COVID-19 diagnosis using AI
- Pleural and Pulmonary Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Thermal Regulation in Medicine
- Diet and metabolism studies
- Hip disorders and treatments
- Cardiac Imaging and Diagnostics
- Lung Cancer Diagnosis and Treatment
- Herpesvirus Infections and Treatments
- Pneumothorax, Barotrauma, Emphysema
- Dermatological and COVID-19 studies
- Cytomegalovirus and herpesvirus research
- Acute Myocardial Infarction Research
- Anesthesia and Sedative Agents
- Neurological and metabolic disorders
- Radiomics and Machine Learning in Medical Imaging
- Orthopaedic implants and arthroplasty
- Airway Management and Intubation Techniques
- Anesthesia and Neurotoxicity Research
- Bone and Joint Diseases
- Intensive Care Unit Cognitive Disorders
Guy's and St Thomas' NHS Foundation Trust
2010-2024
St Thomas' Hospital
2019-2023
University Hospitals Dorset NHS Foundation Trust
2023
Poole Hospital
2023
Methodist Hospital
2021
Ann Arbor Center for Independent Living
2021
University of Michigan
2020
Shionogi (Japan)
2020
Pfizer (United Kingdom)
2020
Pfizer (United States)
2019
Acute respiratory distress syndrome (ARDS) is a common, but under-recognised, critical illness associated with high mortality. An important factor in its under-recognition the variability chest radiograph interpretation for ARDS. We sought to train deep convolutional neural network (CNN) detect ARDS findings on radiographs.CNNs were pretrained 595 506 radiographs from two centres identify common (eg, opacity and effusion), then trained 8072 annotated by multiple physicians using various...
For patients supported with veno-venous extracorporeal membrane oxygenation, the occurrence of intracranial hemorrhage is associated a high mortality. It unclear whether consequence intervention or underlying severe respiratory pathology. In cohort transferred to regional failure center that routinely employs admission brain imaging, we sought 1) prevalence hemorrhage; 2) survival and neurologic outcomes; 3) factors hemorrhage.A single-center, retrospective, observational study.Tertiary...
<h3>Objective</h3> Cerebral oedema is a potentially devastating complication of diabetic ketoacidosis (DKA). The relationship between osmolar changes, acid–base changes and development cerebral during therapy unclear. <h3>Design</h3> Retrospective cohort study on 53 children with severe DKA (mean pH at presentation 6.92±0.08). was diagnosed using neurological status, response to osmotherapy, neuroimaging, classified as: early (occurring ≤1 h after presentation, n=15), late (1–48 h, n=17) or...
Should we aim to intervene and control fever in the critically ill patient? The answer is not straightforward there certainly no universal agreement on subject. This article aims discuss whether should over-ride nature disallow it take it's course, particularly where appears that this evolutionary response invading pathogens actually becoming harmful patient. Also discussed here are physiology of temperature scope our current understanding impact patients manifesting systemic inflammatory...
COVID-19 acute respiratory distress syndrome (ARDS) can be associated with extensive lung damage, pneumothorax, pneumomediastinum and, in severe cases, persistent air leaks (PALs) via bronchopleural fistulae (BPF). PALs impede weaning from invasive ventilation or extracorporeal membrane oxygenation (ECMO). We present a series of patients requiring veno-venous ECMO for ARDS who underwent endobronchial valve (EBV) management PAL. This is single-centre retrospective observational study. Data...
A broncho-cutaneous fistula (BCF) is a communicating tract between the bronchus and cutaneous surface of thoracic wall can be primary presenting sign several disease processes. It has been associated with positive pressure ventilation (PPV), post pneumonectomy, thoracostomy tubes, perforating chest trauma, neoplasia chronic empyema. We report case 45-year-old immunocompetent man severe hypercapnic respiratory failure secondary to BCF as result tuberculosis (TB)-related empyema necessitans....