A5001739918- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Neuroscience and Neuropharmacology Research
- Neural dynamics and brain function
- Esophageal and GI Pathology
- Photoreceptor and optogenetics research
- Geotechnical Engineering and Underground Structures
- Olfactory and Sensory Function Studies
- Thyroid Disorders and Treatments
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Lung Cancer Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Temporomandibular Joint Disorders
- Advanced Chemical Sensor Technologies
- Biochemical Analysis and Sensing Techniques
- Neuroscience and Neural Engineering
- Geotechnical Engineering and Soil Stabilization
- Colorectal and Anal Carcinomas
- Colorectal Cancer Treatments and Studies
- Metallurgy and Material Forming
- Cardiac Imaging and Diagnostics
- Musculoskeletal synovial abnormalities and treatments
- Cancer Research and Treatments
- Cancer Diagnosis and Treatment
Tokushima University
2013-2024
Okayama University
2018-2020
Kanazawa Medical University
2006-2016
National Institute of Technology
2016
Nagasaki University
1987-2014
Shinshu University
2011
Ōtani University
2011
Kyushu University
2011
Ito Hospital
1992-2010
Anan National College of Technology
2010
Abstract Purpose: Angiogenesis plays an important role in a multitude of biological processes including those tumorigenesis and cancer progression. Hypoxia is the prime driving factor for tumor angiogenesis family hypoxia-inducible factors (HIFs) pivotal this process. The HIF has been underscored different carcinomas but yet to be reported colorectal carcinomas. Experimental Design: In study, we examined [HIF-1α (HIF1) HIF-2α (HIF2)] expression 87 curatively resected carcinoma samples,...
Risk analysis of pulmonary complications after extended esophagectomy with three-field lymph node dissection (3FLND) has been little reported in the literature.Risk factors developing postoperative pneumonia and its effects on in-hospital death overall long-term survival were compared between 38 patients who developed 80 did not.Eight died during hospital stay esophagectomy. Seven those 8 pneumonia, whereas 31 110 discharged from (P < 0.01). Pneumonia occurred more frequently elderly 0.01),...
KiSS-1 is a promising candidate tumor-suppressor gene and may play key role in the metastatic cascade. The expression profile of cancer progression are largely unknown most cancers, including gastric cancer. In this study, was evaluated by RNase protection assay localization done situ hybridization 40 cancers their adjacent normal mucosa. For comparison with clinicopathologic characteristics patient prognosis, all patients were divided into 2 groups having high low using median as cutoff...
Magnetic and Mössbauer effect measurements on the nitrides with hcp metal lattice of V, Cr, Mn Fe are carried out as a function composition. Hexagonal VN x hexagonal CrM Pauli paramagnetic. MnN shows antiferromagnetism, while both orthorhombic FeN show ferromagnetism at low temperatures. In these Phases, nitrogen atoms suppress magnetic ordering in consequence reduction moments. As whole, observed types magnetism resemble those their metals spite difference crystal structures. Type II...
Patients with stage T3N0-2M0 gastric carcinoma (n = 108) were studied for relevant prognostic factors. Peritoneal lavage cytology (PLC) was performed in all. In univariate analysis, 5-year survival rates better smaller serosal invasion (diameter < 3.0 cm vs. > or cm, 61% 37%, P 0.05) and fewer metastatic nodes (< 5 6, 57% 29%, 0.05). multivariate only these two factors significant. The predictive value of PLC not shown both analyses. recurrence occurred 14 (22%) 77 patients negative PLC, 3...
Abstract BACKGROUND PTEN is a candidate tumor‐suppressor gene in variety of malignant tumors. The prognostic importance product protein (PTEN) and its correlation with clinicopathologic characteristics have yet to be delineated patients esophageal carcinoma. METHODS Specimens from 97 squamous cell carcinoma were used for the immunohistochemical evaluation expression. RESULTS expression was detected nucleus 48 specimens (49.5%). There statistically significant correlations between nuclear...
Abstract. The northern East China Sea (ECS) serves as a spawning and nursery ground for many species of fish squid. To clarify the basis food web in ECS, we examined nitrate (NO3) dynamics along four latitudinal transects based on stable nitrogen oxygen isotopes NO3 (δ15NNO3 δ18ONO3) temperature–salinity both winter (February 2009) summer (July 2009 July 2011). δ15NNO3 δ18ONO3, which were distinctly different among potential sources, useful clarifying sources its actual usage by...
To evaluate whether patients with subclinical hypothyroidism have a disturbance in lipid metabolism, and supplemental L-thyroxine (L-T4) therapy would improve their parameters, we measured serum levels of thyroid hormones, TSH parameters 34 before 2 months after treatment L-T4. Before treatment, had elevated low density lipoprotein cholesterol (LDL-C) concentrations compared control subjects (P < 0.05). Overall, L-T4 significantly decreased the level 0.01), total (TC; P 0.02), high LDL-C...
Objective Although psychological stress and smoking have been proposed as contributing factors to Graves' disease, their independent roles in the pathogenesis of this disease not determined. We assessed association between by using multivariate analysis. Methods By a matched case-control method, we investigated stressful life events, daily hassles, smoking, drinking habits, coping skills, social support 228 patients (182 women 46 men) with newly diagnosed disease; used conditional maximum...
Structure and function of the brain are use-dependent variables based on "synapse plasticity". Since synapses driven by chemical transmitters, synaptic functions liable to be modified extrinsic chemicals displaying affinities for receptors or modulators. Caffeine is a widely used substance that can invade synapses, has several biochemical metabolic actions activities. This review focuses caffeine changes in structure region hippocampal formation neocortex, which exhibit high synapse...
The aim of this study was to determine the correlation metallothionein (MT) expression with resistance cisplatin and identify prognostic factors in esophageal cancer. Immunostaining for MT performed on specimens squamous cell carcinoma esophagus resected from 68 patients curative intent. evaluated terms clinicopathologic variables, effect cisplatin, patients' survival. Overexpression tumor found 70.6% patients. Stage III IV tumors were more common MT-positive (p = 0.0282) but there no...
We studied whether a patient with Graves' disease will go into remission during antithyroid drug (ATD) treatment. Remission of hyperthyroidism is predicted by smooth decrease in TSH receptor antibody (TRAb) ATD Cytotoxic T cell lymphocyte-associated molecule-4 (CTLA-4) may play an important role the development and its remission. A/G polymorphism at position 49 exon 1 CTLA-4 gene 144 Japanese patients. intended to reveal possible association hyperthyroidism. All patients were treated ATD....