- Bariatric Surgery and Outcomes
- Esophageal and GI Pathology
- Body Contouring and Surgery
- Gastroesophageal reflux and treatments
- Diet and metabolism studies
- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Gastrointestinal motility and disorders
- Obesity and Health Practices
- Gastrointestinal disorders and treatments
- Esophageal Cancer Research and Treatment
- Diabetes Treatment and Management
- Pharmacology and Obesity Treatment
- Helicobacter pylori-related gastroenterology studies
- Diet, Metabolism, and Disease
- Pancreatitis Pathology and Treatment
- Tracheal and airway disorders
- Biliary and Gastrointestinal Fistulas
- Dietary Effects on Health
- Liver Diseases and Immunity
- Cardiovascular Disease and Adiposity
- Dysphagia Assessment and Management
- Gallbladder and Bile Duct Disorders
- Metabolism, Diabetes, and Cancer
- Gastrointestinal Tumor Research and Treatment
Washington Center for Weight Management and Research
2023-2025
NorthShore University HealthSystem
2024
Mayo Clinic in Arizona
2020-2023
Mayo Clinic
2019-2023
WinnMed
2019-2023
Mayo Clinic in Florida
2020-2022
Vanderbilt University Medical Center
2022
RELX Group (Netherlands)
2020
Chonnam National University Hospital
2020
Abstract Objective This study aimed to determine the effects of a long‐acting glucagon‐like peptide‐1 (GLP‐1) receptor agonist, liraglutide, and placebo subcutaneously over 16 weeks on weight gastric functions evaluate associations single‐nucleotide polymorphisms in GLP1R (rs6923761) TCF7L2 (rs7903146) with liraglutide. Methods The conducted randomized, parallel‐group, placebo‐controlled, 16‐week trial escalated 3 mg daily 136 otherwise healthy adults obesity. Weight, emptying solids (GES),...
BackgroundOral monosaccharides and disaccharides are used to measure in vivo human gut permeability through urinary excretion.AimsThe aims were as follows: (1) obtain normative data on small intestinal colonic permeability; (2) assess variance standard 16 g fiber diet performed twice; (3) determine whether dietary influences measurements; (4) present pilot using 2 selected probes patients with diarrhea-predominant irritable bowel syndrome (IBS-D).MethodsSixty healthy female male adults, age...
There are altered mucosal functions in irritable bowel syndrome with diarrhoea (IBS-D); ~30% of patients IBS-D have abnormal bile acid (BA) metabolism (ABAM) and (summarised as BAD).
Goals: We aimed to describe the diagnostic and prognostic performance of transient elastography (TE) magnetic resonance (MRE) in patients with primary biliary cholangitis (PBC). Background: The TE MRE detecting advanced fibrosis PBC predicting outcomes independent existing serologic markers is incompletely understood. Materials Methods: Five hundred thirty-eight consecutive at 3 centers liver stiffness (LS) measurements by (n=286) or (n=332) were reviewed. LS cutoffs for stages determined...
Endoscopic sleeve gastroplasty (ESG) is an effective therapy for class I-II obesity, but there are knowledge gaps in the published literature about its implementation patients with III obesity [body mass index (BMI) ≥ 40 kg/m2].To evaluate safety, clinical efficacy, and durability of ESG adults obesity.This was a retrospective cohort study that used prospectively collected data on BMI kg/m2 who underwent longitudinal lifestyle counseling at two centers expertise endobariatric therapies from...
INTRODUCTION: Cannabidiol (CBD), a CBR2 agonist with limited psychic effects, antagonizes CB1/CB2 receptors. Allelic variation CNR1 (gene for CBR1) rs806378 and FAAH rs324420 were associated altered gut motility sensation. This study aimed to compare the pharmacodynamics clinical effects of 4-week treatment pharmaceutical-grade CBD vs placebo assess interactions gene variants on in patients functional dyspepsia (FD). METHODS: We performed randomized, double-blinded, placebo-controlled (1:1...
The primary obesity surgery endoluminal 2.0 (POSE 2.0) procedure involves full-thickness gastric body plications to narrow the stomach using durable suture anchor pairs. We evaluated POSE as a treatment strategy for nonalcoholic fatty liver disease (NAFLD) in patients with obesity.Adults and NAFLD were prospectively allocated based on their preference undergo lifestyle modification or alone (control). Primary end points improvement controlled attenuation parameter (CAP) resolution of hepatic...
To evaluate the weight loss outcomes of large US cohort patients undergoing endoscopic sleeve gastroplasty (ESG) with or without concomitant anti-obesity (AOM) use. We performed a retrospective analysis adult who underwent ESG from seven different sites, January 1, 2020 to November 30, 2022. Percent total body (%TBWL) and %excess (%EWL) were calculated based on baseline at procedure. Medication use was considered if subject received prescribed AOM during study period. SPSS (version 29.0)...
Endoscopic bariatric therapies can help address widening management gaps in obesity. Their ability to facilitate weight loss is largely tied influences on appetite through perturbations of gastric emptying and accommodation. As these tools gain traction obesity therapy, their physiologic underpinnings require exploration, which may enhance efficacy, tolerance, patient-tailored care.We prospectively assessed consecutive subjects with fluid-filled intragastric balloons (IGBs) ( n = 18) placed...