A5032461371- Neurogenesis and neuroplasticity mechanisms
- Neuroscience and Neuropharmacology Research
- Growth Hormone and Insulin-like Growth Factors
- Nerve injury and regeneration
- Cellular transport and secretion
- Alzheimer's disease research and treatments
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Neuroinflammation and Neurodegeneration Mechanisms
- Sexual Differentiation and Disorders
- Animal Genetics and Reproduction
- Animal Nutrition and Physiology
- Pancreatic function and diabetes
- Birth, Development, and Health
- Parkinson's Disease Mechanisms and Treatments
- Prenatal Substance Exposure Effects
- Insect Utilization and Effects
- Animal and Plant Science Education
- Meat and Animal Product Quality
- Rabbits: Nutrition, Reproduction, Health
- Circadian rhythm and melatonin
- Collagen: Extraction and Characterization
- Fibroblast Growth Factor Research
- Oral and gingival health research
- Diet and metabolism studies
- Retinal Development and Disorders
Kagawa University
2009-2020
Ryukoku University
2020
Oita University
2016
Kyoto Pharmaceutical University
2016
University of Gothenburg
2004-2010
Institute for Biomedicine
2010
Institute of Neurobiology
2008
Hamamatsu University School of Medicine
1995-2003
Osaka Prefecture University
1997-2003
Chiba University
1987
Black soldier fly (BSF) larvae and pre-pupae could be satisfactorily raised on household organic waste used as poultry feed, offering a potential sustainable way to recycle untapped resources of waste. The present study was conducted determine if whole (non-defatted) BSF experimental substitute soybean meal oil ingredients for laying hen diets. While no significant differences in feed intake the egg-laying rate hens were observed throughout experiment, egg weight eggshell thickness greater...
The residue generated by the black soldier fly (Hermetia illucens, BSF) during processing of organic waste is considered a suitable crop fertilizer. However, no detailed studies have investigated fertilizer value obtained from household waste. In this study, experimental (EHOW) was processed BSF at 200 mg EHOW per head for 15 days 27 °C. To evaluate larvae production (BSFR), chemical composition and microbiota were analyzed, Komatsuna (Brassica rapa var. perviridis) cultivation tests...
Hypoxia promotes neural stem cell proliferation, the mechanism of which is poorly understood. Here, we have identified nuclear orphan receptor TLX as a mediator for proliferation and pluripotency progenitors upon hypoxia. We found an enhanced early protein expression under hypoxia potentiating sustained progenitors. Moreover, induction in differentiating conditions leads to cell-like phenotype, along with coexpression markers. Following hypoxia, recruited Oct-3/4 proximal promoter,...
Abstract Excessive intake of sugar‐rich foods leads to metabolic syndrome. d ‐Psicose (Psi) not commonly found in nature, is noncalorie sweetener with a suppressive effect on the blood glucose level. Thus, Psi has potential be utilized as sucrose (Suc) replacer foods, including meringue‐based confectionery (MBC). In this study, we investigated physical and chemical properties meringue. Meringue was made by whipping egg white Suc (at weight ratio 1:1) baking at 93 °C for 2 h. Thirty percent...
Abstract A line of transgenic rats (heterozygotes) carrying a chimeric gene comprising regulatory portion murine whey acidic protein and structural human GH (hGH) genes developed severe obesity with age. To characterize physiological mechanisms that lead to fat accumulation, an array parameters related were studied. Blood hGH levels continuously low, endogenous rat secretion was suppressed, the pulsatility in peripheral absent. Plasma glucose, insulin, triglyceride, FFA male significantly...
Effects of early postnatal ethanol exposure on brain-derived neurotrophic factor (BDNF) mRNA expression in the rat hippocampus were investigated. Wistar rats assigned to either treatment (ET) separation control (SC) or mother-reared (MRC) groups. Ethanol was achieved by a vapor inhalation method for 3 hours day between days (PND) 1015. On PND 16, 20, 30, and 60, BDNF determined using real-time RT-PCR analysis. There significant age-related increase 3060 MRC animals. The ET increased at both...
Collagen in an eggshell membrane is important for egg preservation, medical burn treatment and manufacturing of cosmetics. Because collagen the little, it a need to improve accumulation develop these applications. Wood charcoal powder with vinegar (WCV) natural substance that improves poultry production. In hen fed WCV, total increased increase dietary WCV significantly 1.0% group (p < 0.05). Scanning light microscopic images revealed this had thicker membranes fine mesh structure composed...
Pituitary glands of chicken, from stages 20 (70 approximately 72 h incubation) to 46 (20 days) Hamburger and Hamilton (1951), were studied by immunocytochemical histological stainings India ink injection into blood vessels. Using the distribution pattern 6 types immunoreactive adenohypophyseal cells location pituitary stalk as guideposts, we found how specific areas in epithelium Rathke's pouch differentiate regions adenohypophysis at days. In sagittal plane, walls tentatively divided upper...
We investigated mechanisms of the p73α-mediated repression platelet-derived growth factor β-receptor (PDGFRB) promoter caused by its interaction with NF-Y. Treatment cells histone deacetylase (HDAC) inhibitor, Trichostatin A, increases PDGFRB activity through CCAAT motif and counteracts p73α. Activation co-activator p300 also occurs motif. Expression p73α both p300- P/CAF-mediated activation promoter, expression or P/CAF attenuates activity. In concordance, decreases p300-mediated...
Abstract Herein, we show that both exogenously transfected and endogenously activated p53 repress promoter activity expression of PDGFRB. binds the proximal containing CCAAT motif as examined by EMSA chromatin immunoprecipitation. However, gradual induction in tet‐onSAOS2 cells resulted a transient increase PDGFRB‐promoter its expression. As binding to increased, previously bound p73, ΔNp73, c‐Myc, HDAC1 HDAC4 were dismissed from repressed promoter, p300 was recruited. The therefore induced...
We comprehensively evaluated meat quality in chickens fed a diet consisting of wood charcoal and vinegar (WCV) using food scientific histological approaches. In culled hens, lipid fatty acid Musculus semimembranosus, cooking loss sensory tests whole thigh meat, texture breast were observed. male broilers, cross section M. semimembranosus was used for observations on muscle area, perimysium, non-collagen total protein collagen content, anti-collagen I III reactions. frozen conventional...
The present study was undertaken to evaluate the effects of monocular enucleation on calbindin-D 28k (CB) and c-Fos immunoreactive (IR) neurons in lateral geniculate nucleus (LGN) complex adult rats. resulted neuronal degeneration decrease LGN complex. Our demonstrated a CB-IR density contralateral side ventral (vLGN) dorsal (dLGN) until 12 weeks post-enucleation (PE). On ipsilateral side, dLGN vLGN showed significant continuous 48 PE, respectively. In an additional experiment, c-Fos-IR were...
We aimed to elucidate the mechanism of action estrogenic endocrine disruptors and rescue reproductive function, particularly responsiveness testes eCG and/or activin A (ACT) after establishing disorders. Newborn male mice (n = 29) were randomly divided into an untreated group three treatment groups that received diethylstilbestrol (DES; 100 mug per animal) subcutaneously on Postnatal Day 3 establish disorders daily with PBS (controls: DES + PBS), (eCG group: eCG), or ACT ACT) at 6-8 wk age...
This study investigates the combined effect of silicic acid and bamboo vinegar compound liquid (SPV) on growth intestinal histological alterations in poultry. Forty-eight 7-day-old male Sanuki Cochin chickens were fed a commercial mash diet supplemented with SPV at 0, 0.1, 0.2, 0.3% level ad libitum for 112 days. Body weight gain tended to improve increased concentrations dietary SPV, although these results not statistically significant (P<0.1). Tissue observation by light microscopy...