A5080156950- Spinal Dysraphism and Malformations
- Spinal Fractures and Fixation Techniques
- Veterinary Orthopedics and Neurology
- Head and Neck Surgical Oncology
- Veterinary Oncology Research
- Fetal and Pediatric Neurological Disorders
- Spine and Intervertebral Disc Pathology
- Cerebrospinal fluid and hydrocephalus
- Meningioma and schwannoma management
- Infectious Diseases and Tuberculosis
- Diphtheria, Corynebacterium, and Tetanus
- Orthopedic Infections and Treatments
- Cerebral Venous Sinus Thrombosis
- Infectious Encephalopathies and Encephalitis
- Sinusitis and nasal conditions
- Trigeminal Neuralgia and Treatments
- Glaucoma and retinal disorders
- Bacterial Infections and Vaccines
- Congenital Anomalies and Fetal Surgery
- Spinal Cord Injury Research
- Epilepsy research and treatment
- Neuroscience and Neuropharmacology Research
- Neurological diseases and metabolism
- Veterinary medicine and infectious diseases
- Surgical Sutures and Adhesives
Animal Free Research UK
2022-2025
University of Hertfordshire
2019
Royal Veterinary College
2012-2015
University of London
2012
University of Cambridge
2011-2012
The disease complex Chiari-like malformation (CM) and syringomyelia (SM) has been associated with the development of neuropathic pain (NeP), commonly affects Cavalier King Charles spaniels (CKCS). This prospective cohort study followed 48 CKCSs CM and/or SM clinical signs suggestive NeP for a period 39 (±14.3) months from diagnosis. At end study, 36 dogs were still alive; five died an unrelated or unknown cause, seven euthanased due to severe NeP. During follow-up period, scratching, facial...
ABSTRACT Background The comparative effectiveness of radiotherapy and surgery for treating intracranial meningioma is unknown. Objectives To compare survival after treatment suspected by either or radiotherapy. Animals Two hundred eighty‐five companion dogs with meningiomas presenting to 11 specialty clinics in three countries. Methods Parallel cohort comparison study on retrospective data. Dogs diagnosed board‐certified veterinary neurologists radiologists treated were identified through...
A 14-year-old male domestic shorthair cat presented with an acute onset of aggressive behaviour, fear and hypersalivation. Neurological examination revealed bilateral mydriasis left-sided facial twitching hemiparesis. Magnetic resonance imaging (MRI) showed moderate symmetrical T2-hyperintensity along the entire hippocampus asymmetric in pyriform lobes. Marked contrast enhancement was evident on post-contrast T1-weighted images. The partial complex seizures were refractory to medical...
To date there is no evidence-based data for efficacious treatment of neuropathic pain in dogs with Chiari-like malformation (CM) and syringomyelia (SM). The objective this prospective cross-over study was to compare the effect gabapentin versus topiramate, as an add-on carprofen, on quality life (QoL) experiencing signs due CM/SM. A visual analogue scale (VAS) used assess QoL: (1) day 0; (2) after 1 week carprofen only; (3) 2 weeks gabapentin; (4) topiramate. No significant difference...
Meningioma is the most common primary brain neoplasm in dogs. Further information required regarding expected long-term prognosis of dogs following surgical resection an intracranial meningioma together with influence adjunctive therapies. Whilst there have been several studies reporting outcome surgery alone, use ultrasonic aspirator, combined radiotherapy and addition hydroxyurea, it currently unclear which type therapy associated favourable outcomes. The objective this study to describe...
Abstract Pseudoabducens paralysis resulting in resting medial strabismus (esotropia) is a rare consequence of contralateral paramedian thalamic ischemic infarction people. To date, esotropia has been reported dogs association with ipsilateral abducens neuropathy or extraocular myopathy, but not secondary to lesions. A 7‐year‐old male neutered Border Collie and 12‐year‐old female cross‐breed dog were presented peracute nonprogressive vestibular ataxia. Neurological examination identified...
To describe the clinical presentation, advanced imaging findings, and short- long-term outcomes in dogs with intracranial empyema.Retrospective case series.Client-owned diagnosed empyema.Medical records from 2 referral hospitals were searched for empyema. be included this study, had to fulfill 1 or more of following 3 inclusion criteria: a magnetic resonance (MRI) scan space occupying accumulation extra-axial material suggestive empyema, cerebrospinal fluid analysis direct visualization...
Abstract Objective To determine cutoff values for the diagnosis of atlantoaxial instability (AAI) based on cross‐sectional imaging in small‐breed dogs. Study design Retrospective multicenter study. Sample population Client‐owned dogs ( n = 123) and 28 cadavers. Methods Dogs were assigned to three groups: a control group, “potentially unstable” an AAI‐affected according findings clinical signs. The ventral compression index (VCI), cranial translation ratio (CTR), C1‐C2 overlap, angle,...
Objective The main purpose of this study was to define criteria systemically describe craniovertebral junction (CVJ) anomalies and report the prevalence CVJ in small breed dogs with without atlantoaxial instability (AAI). Materials Methods Retrospective multicentre matched case–control evaluating magnetic resonance imaging computed tomographic images AAI for presence anomalies. Results One hundred twenty-two were enrolled (61 61 AAI). Only had dens axis such as separation (n = 20) or a...
A 10‐month‐old dachshund was presented with a recent history of episodic muscle rippling and generalised stiffness. An uncoordinated gait present since eight weeks age. On presentation the dog showed cerebellar‐like ataxia poor menace responses. Myokymic contractions were visible in appendicular truncal muscles neuromyotonic discharges detected by electromyography. Central components brain auditory evoked potentials absent onset latencies tibial sensory‐evoked recorded at lumbar...
Een vier maanden oude Engelse buldog werd aangeboden met klachten van acute faciale spiertrekkingen, scheve kopstand en een abnormaal bewustzijn. Het neurologisch onderzoek was indicatief voor multifocale hersenaandoening. hematologisch biochemisch normaal. Magnetische resonantie de hersenen onthulde uitgesproken vergroting linker laterale ventrikel, bijkomend het calvarium op dit niveau. Er waren ook periventriculaire letsels T2W- FLAIR-beelden zichtbaar matige contrastopname. Analyse...
Abstract Objective The aim of this study was to evaluate differences in paraspinal musculature between dogs with and without atlantoaxial instability (AAI) using computed tomography scans. Study Design Retrospective multicentre evaluating transverse reconstructed scans 83 small breed (34 49 AAI) for the cross-sectional area at three levels (Occiput/C1, mid-C1, mid-C2). Ratio moments, dorsal-to-ventral muscle-area ratios (d-v-ratio) dorsal ventral C2 height (d-C2-ratio v-C2-ratio) were...
A six-year-old, male, neutered Cocker spaniel was referred for a three-week history of progressive thoracic limb stiffness. The dog became non-ambulatory due to severe stiffness, which exacerbated by external stimuli. pelvic limbs appeared be normal. Based on the and physical examination, presumptive diagnosis focal tetanus made. treated supportively with antitoxin, antimicrobials, sedation muscle relaxants; however, this treatment did not control spasms adequately. Magnesium sulphate added...