- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Child and Adolescent Psychosocial and Emotional Development
- Attention Deficit Hyperactivity Disorder
- Tryptophan and brain disorders
- Adolescent and Pediatric Healthcare
- Mental Health and Psychiatry
- Functional Brain Connectivity Studies
- Genetics and Neurodevelopmental Disorders
- Autism Spectrum Disorder Research
- Maternal Mental Health During Pregnancy and Postpartum
- Stress Responses and Cortisol
- Child Abuse and Trauma
- Diet and metabolism studies
- Cannabis and Cannabinoid Research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Suicide and Self-Harm Studies
- Psychiatric care and mental health services
- Genetic Associations and Epidemiology
- Obsessive-Compulsive Spectrum Disorders
- Personality Disorders and Psychopathology
- Epilepsy research and treatment
- Treatment of Major Depression
- Pharmacological Effects and Toxicity Studies
- Nuclear Receptors and Signaling
Instituto de Salud Carlos III
2020-2024
Institut d'Investigació Sanitària Pere Virgili
2016-2024
Institut Pere Mata
2016-2024
Centro de Investigación Biomédica en Red de Salud Mental
2015-2024
Universitat Rovira i Virgili
2016-2024
Medical Research Network
2016-2024
Centre for Biomedical Network Research on Rare Diseases
2016-2023
Parc Sanitari Sant Joan de Déu
2019-2020
Hospital Clínic de Barcelona
2006-2019
Centro de Investigación Biomédica en Red
2018
Article AbstractObjective: To study the prevalence of suicide attempts and factors associated with risk for during first episode psychosis, to identify early predictors over a 24-month follow-up period in an early-onset, first-episode psychosis cohort.Method: 110 subjects their aged between 9 17 years were assessed by using DSM-IV diagnostic interview Schedule Affective Disorders Schizophrenia School-Age Children-Present Lifetime Version battery clinical instruments at baseline 12 24 months....
Schizophrenia (SZ) and bipolar disorder (BD) share clinical features, genetic risk factors neuroimaging abnormalities. There is evidence of disrupted connectivity in resting state networks patients with SZ BD their unaffected relatives. Resting are known to undergo reorganization during youth coinciding the period increased incidence for both disorders. We therefore focused on characterizing network at familial or identify alterations arising this period. measured resting-state functional a...
Summary We aim to investigate whether temporal origin of epilepsy increases the risk developing a psychiatric disorder and more specifically major depressive disorder. The lack standardized diagnostic instruments methodologic differences between studies highlight fact that this issue warrants further, systematic, study. Three‐hundred eight patients with complex partial seizures were classified according or extratemporal origin, following Commission on Classification Terminology International...
Studies in child and adolescent offspring of patients with schizophrenia or bipolar disorders may help understand the influence neurodevelopmental factors on premorbid phenotype these disorders.To assess whether a combination discriminates between young (SzO) disorder (BpO) community controls (CcO). To association rates psychiatric diagnoses high risk (HR) youth.One hundred thirty-three HR (47 SzO 86 BpO) 84 CcO, aged 6-17, underwent cross-sectional clinical, neurocognitive, structural...
There is a dearth of research focusing on factors associated with suicide attempts. High rates atypical depression have been reported in studies including unipolar and bipolar II patients. In this study, the association between attempt depression, addition to other major risk factors, was evaluated 390 I out-patients.Variables were defined according DSM-IV criteria, assessed Structured Interview for (axis II). History obtained through interviews patients relatives. Attempters non-attempters...
Background The affective dimension has scarcely been studied in early‐onset psychosis. Our aims were to investigate the prevalence and type of symptoms prodromal acute phases psychosis examine their relationship with suicide. We also sought establish whether presence premorbid antecedents or during phase might predict a later diagnosis bipolar disorder ( BP ) schizophrenia SZ ). Method Participants 95 youths, aged 9–17 years, experiencing first episode psychotic FEP according DSM ‐ IV...
Abstract Aim In the current cross‐sectional study, we aimed to explore whether thyroid function or autoimmunity are associated with psychopathological symptoms and social functioning in patients early psychosis. We hypothesized that severity is greater those positive autoimmunity. Methods studied 70 outpatients psychosis (<3 years of illness) 37 healthy subjects. Psychopathological (positive, negative, disorganized, excited depressive) were assessed. Thyroid (antibodies against peroxidase...
Aim Despite the interest in psychosis risk syndrome (PRS) children and adolescents, information on this population is scarce. Methods Prospective naturalistic multi‐site study which 10‐ to 17‐year‐old help‐seeking subjects who met PRS criteria (positive or negative attenuated symptoms; brief limited intermittent psychotic genetic schizotypal personality disorder plus impairment functioning) were included, along with 45 age sex‐matched healthy controls (HC). All clinically functionally...
This study aimed to assess the relationship between childhood maltreatment (CM), objective and subjective cognition, psychosocial functioning in adults with first-episode psychosis (FEP) by examining moderating role of cognitive reserve (CR). A secondary was explore whether unique CM subtypes (physical and/or emotional abuse, sexual physical neglect) were driving this relationship.
Summary Purpose: Whether a specific lesion such as mesial temporal sclerosis (MTS) increases the risk for mood disorder in epilepsy remains subject to debate. Despite evidence of limbic system involvement genesis emotional symptoms, recent studies fail support an association between depression and MTS. We aimed clarify this controversial issue by overcoming prior methodologic limitations, hypothesizing that rates major depressive (MDD) would be higher patients with Methods: Three hundred...
To investigate rates of psychopathology in the offspring subjects with bipolar disorder (BP-offspring) compared to healthy (HC-offspring) a Spanish sample and study possible predictors BP-offspring.Fifty BP-offspring from 36 families 25 HC-offspring families.Psychopathology was HC-offspring. Factors associated DSM-IV axis I disorders were analyzed using logistic regression.Half fulfilled diagnostic criteria for at least one attention-deficit/hyperactivity (30%), anxiety (14%) affective (10%)...