- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Child and Adolescent Psychosocial and Emotional Development
- Functional Brain Connectivity Studies
- Adolescent and Pediatric Healthcare
- Attention Deficit Hyperactivity Disorder
- Cannabis and Cannabinoid Research
- Maternal Mental Health During Pregnancy and Postpartum
- Advanced Neuroimaging Techniques and Applications
- Neurotransmitter Receptor Influence on Behavior
- Tryptophan and brain disorders
- Mental Health Research Topics
- Autism Spectrum Disorder Research
- Traumatic Brain Injury Research
- Infant Development and Preterm Care
- Personality Disorders and Psychopathology
- Treatment of Major Depression
- Multiple Sclerosis Research Studies
- Neuroethics, Human Enhancement, Biomedical Innovations
- Neonatal and fetal brain pathology
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuroendocrine regulation and behavior
- Psychiatric care and mental health services
- Sleep and Wakefulness Research
- Digital Mental Health Interventions
Universidad Complutense de Madrid
2019-2025
Université Clermont Auvergne
2024
Institut Pascal
2024
Hospital General Universitario Gregorio Marañón
2014-2023
Hospital Clínico San Carlos
2023
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2023
Centro de Investigación Biomédica en Red de Salud Mental
2014-2022
Centro de Investigación Biomédica en Red
2019
Centre for Biomedical Network Research on Rare Diseases
2016
Although there is recent evidence that cells from the peripheral immune system can gain access to central nervous in certain conditions such as multiple sclerosis, their role has not been assessed psychosis. Here, we aimed explore whether blood cell count was associated with brain volume and/or clinical symptomatology. A total of 218 participants (137 first-episode psychosis patients [FEP] and 81 healthy controls [HC]) were included study. For each participant, a T1 structural image...
Studies in child and adolescent offspring of patients with schizophrenia or bipolar disorders may help understand the influence neurodevelopmental factors on premorbid phenotype these disorders.To assess whether a combination discriminates between young (SzO) disorder (BpO) community controls (CcO). To association rates psychiatric diagnoses high risk (HR) youth.One hundred thirty-three HR (47 SzO 86 BpO) 84 CcO, aged 6-17, underwent cross-sectional clinical, neurocognitive, structural...
The human brain can adapt to overcome injury even years after an initial insult. One hypothesis states that early survivors, by taking advantage of critical periods high plasticity during childhood, should recover more successfully than those who suffer later in life. This has been challenged recent studies showing worse cognitive outcome individuals with injury, compared working memory particularly affected. We invited suffered perinatal (PBI) for fMRI/diffusion MRI tractography study and...
Tobacco is a highly prevalent substance of abuse in patients with psychosis. Previous studies have reported an association between tobacco use and schizophrenia. The aim this study was to analyze the relationship first-episode psychosis (FEP), age at onset psychosis, specific diagnosis psychosis.The sample consisted 1105 FEP 1355 controls from European Network National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI) study. We assessed Alcohol Questionnaire performed...
Abstract Aim Borderline personality disorder and severe emotion dysregulation in adolescence is a major public health concern. Dialectical Behaviour Therapy promising treatment for suicidality adolescents. The aim of this work to present an adaptation intervention the Spanish national system, Actions Treatment Adolescent Personality (ATraPA). Method Data consists description different ATraPA subprogrammes, including interventions adolescents aged 13 17 their families. Participants were...
First-episode psychosis (FEP) patients show structural brain abnormalities at the first episode. Whether cortical changes that follow a FEP are progressive and whether age onset modulates these remains unclear. This is multicenter MRI study in deeply phenotyped sample of 74 with wide range (15-35 years) 64 neurotypical healthy controls (HC). All participants underwent two scans 2-year follow-up interval. We computed longitudinal percentage change (PC) for thickness (CT), surface area (CSA)...
Abstract Background Use of illegal stimulants is associated with an increased risk psychotic disorder. However, the impact stimulant use on odds first-episode psychosis (FEP) remains unclear. Here, we aimed to describe patterns and examine their FEP. Methods We included patients FEP aged 18–64 years who attended psychiatric services at 17 sites across 5 European countries Brazil, recruited controls representative each local population (FEP = 1130; 1497). Patterns were described. computed...
<title>Abstract</title> Introduction Unplanned pregnancies are frequent in women with bipolar disorder (BD) while perinatal period is associated a higher risk of relapse. Effective contraception during childbearing age BD could reduce the unplanned pregnancy and its consequences. The present study studied prevalence contraceptive use which sociodemographic clinical variables affect BD. Methods 796 (18-50 years old) were recruited evaluated by MONTRA survey France among hospital consultant...
Introduction Extremely preterm newborns - EPTN (born ≤28 weeks gestational age) are at increased risk of developing autism spectrum disorders (ASD). Demographic and perinatal factors associated with ASD in understudied. Objectives (i) In born full-term healthy controls (HC), to characterize the emergence traits autistic symptom load age 18 months; (ii) EPTN, identify influence characteristics such as sex on corrected-age months. Methods Observational, longitudinal, prospective, 18-month...
Abstract Background Cannabis use and familial vulnerability to psychosis have been associated with social cognition deficits. This study examined the potential relationship between cannabis cognitive biases underlying functioning in patients first episode (FEP), their siblings, controls. Methods We analyzed a sample of 543 participants FEP, 203 1168 controls from EU-GEI using correlational design. used logistic regression analyses examine influence clinical group, lifetime frequency, potency...