Mónica Martínez‐Cengotitabengoa
- Bipolar Disorder and Treatment
- Tryptophan and brain disorders
- Schizophrenia research and treatment
- Stress Responses and Cortisol
- Maternal Mental Health During Pregnancy and Postpartum
- Circadian rhythm and melatonin
- Psychological and Temporal Perspectives Research
- Child and Adolescent Psychosocial and Emotional Development
- Sleep and related disorders
- Pharmaceutical Practices and Patient Outcomes
- Nerve injury and regeneration
- Neuroinflammation and Neurodegeneration Mechanisms
- Autism Spectrum Disorder Research
- Balance, Gait, and Falls Prevention
- Obsessive-Compulsive Spectrum Disorders
- COVID-19 and Mental Health
- Smoking Behavior and Cessation
- Treatment of Major Depression
- Birth, Development, and Health
- Digital Mental Health Interventions
- Attention Deficit Hyperactivity Disorder
- Influenza Virus Research Studies
- Family Caregiving in Mental Illness
- Pharmacological Effects and Toxicity Studies
- Vaccine Coverage and Hesitancy
University of the Basque Country
2016-2025
Osakidetza
2021-2025
University of East Anglia
2020-2024
Ben-Gurion University of the Negev
2022
BioCruces Health research Institute
2022
Hospital Universitario Araba
2012-2021
Centro de Investigación Biomédica en Red de Salud Mental
2011-2019
University of Helsinki
2019
Helsinki University Hospital
2019
University of Calgary
2019
Schizophrenia is a chronic syndrome of unknown etiology, predominantly defined by signs psychosis. The onset the disorder occurs typically in late adolescence or early adulthood. Efforts to study pathophysiological mechanisms stages disease are crucial order prompt intervention. Case-control first-episode psychotic (FEP) patients and matched controls. We recruited 117 during first year after their FEP according DSM-IV criteria 106 gender-, race-, age-matched controls between September 2010...
Abstract Background Our objective is to determine the activity of antioxidant defense system at admission in patients with early onset first psychotic episodes compared a control group. Methods Total status (TAS) and lipid peroxidation (LOOH) were determined plasma. Enzyme activities total glutathione levels erythrocytes 102 children adolescents episode 98 healthy controls. Results A decrease was found patients, measured as decreased TAS levels. Lipid damage peroxidase higher than study...
Previous studies have indicated systemic deregulation of the proinflammatory or anti-inflammatory balance in individuals with first-episode psychosis (FEP) that persists 12 months later. To identify potential risk/protective factors and associations symptom severity, we assessed possible changes plasma levels neurotrophins (brain-derived neurotrophic factor [BDNF] nerve growth [NGF]) their receptors peripheral blood mononuclear cells (PBMCs). Expression 2 forms BDNF (active TrkB-FL...
Bauer M, Glenn T, Alda Andreassen OA, Ardau R, Bellivier F, Berk Bjella TD, Bossini L, Del Zompo Dodd S, Fagiolini A, Frye MA, Gonzalez‐Pinto Henry C, Kapczinski Kliwicki König B, Kunz Lafer Lopez‐Jaramillo Manchia Marsh W, Martinez‐Cengotitabengoa Melle I, Morken G, Munoz Nery FG, O’Donovan Pfennig Quiroz D, Rasgon N, Reif Rybakowski J, Sagduyu K, Simhandl Torrent Vieta E, Zetin Whybrow PC. Impact of sunlight on the age onset bipolar disorder. Bipolar Disord 2012: 14: 654–663. © 2012 The...
The objective of the study is to examine association baseline total antioxidant status (TAS) and glutathione (GSH) levels with short- long-term cognitive functioning in patients early onset first-episode psychosis, comparing affective non-affective psychoses. We analysed 105 an onset-first episode psychosis (age 9-17 years) 97 healthy controls. Blood samples were taken at admission for measurement TAS GSH, performance was assessed 2years follow-up. Regression analysis used assess...
Purpose: It is well established that the COVID-19 pandemic has increased incidence of depressive symptoms in general population. So far, there are no studies analyzing how this affected prescription antidepressants. Methods: We retrospectively estimated new cases depression by prescriptions antidepressive agents over a period 6 years distributed three periods 2 each: pre-pandemic, pandemic, and post-pandemic, running from March 2018 to February 2024. This research was conducted healthcare...
This study aimed to examine factors associated with treatment adherence in first-episode psychosis (FEP) patients followed up over 8 years, especially involuntary first admission and stopping cannabis use.This prospective, longitudinal of FEP collected data on symptoms, adherence, functioning, substance use. Adherence was the main outcome variable categorized as 'good' or 'bad'. Cannabis use during follow-up stratified continued use, stopped never used. Bivariate logistic regression models...
Previous studies indicated a systemic deregulation of the pro-/antiinflammatory balance in subjects after 6 months first psychotic episode. This disruption was reexamined 12 diagnosis to identify potential risk/protective factors and associations with symptom severity. Eighty-five were followed during determination same mediators carried out plasma peripheral blood mononuclear cells. Multivariate logistic regression analyses used factors. Multiple linear models performed detect change each...
Two common approaches to identify subgroups of patients with bipolar disorder are clustering methodology (mixture analysis) based on the age onset, and a birth cohort analysis. This study investigates if effect will influence results using large, international database.The database includes 4037 diagnosis I disorder, previously collected at 36 collection sites in 23 countries. Generalized estimating equations (GEE) were used adjust data for country median age, some models, cohort....
Objectives To explore the link between cytokines and suicide attempts their relationship with psychological aspects of this complex multifactorial phenomenon.Methods 96 participants, including 20 patients a recent attempt diagnosis Major Depression Disorder (MDD), 33 MDD lifetime history attempt, 23 non-attempter patients, healthy controls underwent an assessment on depressive symptoms, global functioning, aggressive behaviour, presence abuse attention performance. Additionally, all...