A5019570575- Schizophrenia research and treatment
- Functional Brain Connectivity Studies
- Bipolar Disorder and Treatment
- Mental Health Research Topics
- Mental Health and Psychiatry
- Tryptophan and brain disorders
- Neurotransmitter Receptor Influence on Behavior
- Obsessive-Compulsive Spectrum Disorders
- Attention Deficit Hyperactivity Disorder
- Child and Adolescent Psychosocial and Emotional Development
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neural and Behavioral Psychology Studies
- Electroconvulsive Therapy Studies
- Diet and metabolism studies
- COVID-19 and Mental Health
- Neural dynamics and brain function
- Advanced Neuroimaging Techniques and Applications
- Cannabis and Cannabinoid Research
- Digital Mental Health Interventions
- Autism Spectrum Disorder Research
- Treatment of Major Depression
- Substance Abuse Treatment and Outcomes
- Stress Responses and Cortisol
- Personality Disorders and Psychopathology
- Child Abuse and Trauma
Universidad Complutense de Madrid
2016-2025
Centre for Biomedical Network Research on Rare Diseases
2019-2025
Centro de Investigación Biomédica en Red de Salud Mental
2016-2025
Research Institute Hospital 12 de Octubre
2016-2025
Instituto de Salud Carlos III
2009-2025
Hospital General De Zona
2018-2025
Mexican Social Security Institute
2024-2025
Hospital Universitario 12 De Octubre
2009-2024
Università degli Studi di Enna Kore
2024
Hospital Virgen de la Luz
2024
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<h2>ABSTRACT</h2><h3>Background</h3> We aim to assess COVID-19 outbreak-related emotional symptoms, identify gender differences, and study the relationship between state environmental features in elderly. <h3>Methods</h3> conducted a cross-sectional starting on March 29 April 5, 2020 based national online survey using snowball sampling techniques. Symptoms of anxiety (Hamilton Anxiety Scale), depression (Beck Depression Inventory) acute stress (Acute Stress Disorder were compared people over...
Abstract Objective We aim to explore the differential presence of symptoms anxiety, depression, and acute stress between men women during COVID‐19 outbreak, study relationship these two environmental variables, coexistence, violence. Methods conducted a cross‐sectional starting on March 29 April 5, 2020, based national online survey using snowball sampling techniques. Symptoms anxiety (Hamilton Anxiety Scale), depression (Beck Depression Inventory), (Acute Stress Disorder Inventory) were...
Background: Although many studies have established a close relation between impulsivity and alcohol use disorders, little is known about the role of behavioral in development these disorders. Objectives: To determine 2 laboratory paradigms Methods: Follow‐up study carried out with 471 participants diagnosed as heavy drinkers (HD) followed‐up for 4 years. Initially, they were compared healthy control group. Assessment was Continuous Performance Test (CPT), Stop‐Signal Task (SST) assessed...
Schizophrenia is a chronic syndrome of unknown etiology, predominantly defined by signs psychosis. The onset the disorder occurs typically in late adolescence or early adulthood. Efforts to study pathophysiological mechanisms stages disease are crucial order prompt intervention. Case-control first-episode psychotic (FEP) patients and matched controls. We recruited 117 during first year after their FEP according DSM-IV criteria 106 gender-, race-, age-matched controls between September 2010...
Abstract Background Social cognition has been associated with functional outcome in patients first episode psychosis (FEP). also neurocognition and cognitive reserve. Although reserve, neurocognitive functioning, social cognition, are related, the direction of their associations is not clear. Therefore, main aim this study was to analyze influence as a mediator between reserve domains on functioning FEP both at baseline 2 years. Methods The sample composed 282 followed up for To whether...
Abstract Background and Hypothesis A pro-inflammatory phenotype has been related to psychotic disorders. The neutrophil-lymphocyte ratio (NLR) is an accessible biomarker that could be helpful characterize this systemic inflammation state. Study Design This study evaluated the NLR in a cohort of 310 subjects with first episode psychosis (FEP) matched group 215 healthy controls, recruited 16 Spanish centers participating PEPs Project. We investigated measures over 2 years prospective,...
Cognitive dysfunction in bipolar disorder has been well-established cross-sectional studies; however, there are few data regarding the longitudinal course of cognitive performance disorder. The aim this study was to examine function a sample euthymic patients with during five-year follow-up period.Eighty outpatients DSM-IV diagnosis and 40 healthy control comparison subjects were neuropsychologically assessed at baseline (T1) then five years (T2). A neurocognitive battery including main...
Previous studies have indicated systemic deregulation of the proinflammatory or anti-inflammatory balance in individuals with first-episode psychosis (FEP) that persists 12 months later. To identify potential risk/protective factors and associations symptom severity, we assessed possible changes plasma levels neurotrophins (brain-derived neurotrophic factor [BDNF] nerve growth [NGF]) their receptors peripheral blood mononuclear cells (PBMCs). Expression 2 forms BDNF (active TrkB-FL...
In the last 2 decades, several neuroimaging studies investigated brain abnormalities associated with early stages of psychosis in hope that these could aid prediction onset and clinical outcome. Despite advancements field, has yet to deliver. This is part explained by use univariate analytical techniques, small samples lack statistical power, external validation potential biomarkers, integration nonimaging measures (eg, genetic, clinical, cognitive data). PSYSCAN an international,...
Aims: To determine the clinically ascertained variables that are related to satisfactory response naltrexone (NTX) treatment of alcohol dependence after detoxification. Methods: The use intake and outcome were measured in a randomized 3-month open-controlled trial comparing effects plus psychotherapy versus alone on maintenance abstinence final 28 days ( n = 336, all male). Results: Predictors positive NTX family history alcoholism P 0.010), early age at onset drinking problems 0.014)...