Victoria Rodríguez
A5072400429- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Genetic Associations and Epidemiology
- Cannabis and Cannabinoid Research
- Mental Health Treatment and Access
- Child and Adolescent Psychosocial and Emotional Development
- Mental Health Research Topics
- Substance Abuse Treatment and Outcomes
- Mental Health and Psychiatry
- Tryptophan and brain disorders
- Functional Brain Connectivity Studies
- Health Policy Implementation Science
- Epigenetics and DNA Methylation
- Child Abuse and Trauma
- COVID-19 and Mental Health
- Maternal Mental Health During Pregnancy and Postpartum
- Treatment of Major Depression
- Psychosomatic Disorders and Their Treatments
- Zebrafish Biomedical Research Applications
- Pancreatitis Pathology and Treatment
- Cognitive Abilities and Testing
- Neurogenesis and neuroplasticity mechanisms
- Adolescent and Pediatric Healthcare
- Neuroinflammation and Neurodegeneration Mechanisms
- Diet and metabolism studies
King's College London
2018-2025
Baylor College of Medicine
2023-2024
North East London NHS Foundation Trust
2024
Texas A&M University
2023
Pontificia Universidad Católica de Chile
2020-2022
Hospital de Tortosa Verge de la Cinta
2021
Hospital Universitari Sant Joan D'Alacant
2016-2019
University of Concepción
2015-2019
University of Chicago
2014
University Hospitals Cleveland Medical Center
2008
Cannabis use is associated with increased risk of later psychotic disorder but whether it affects incidence the remains unclear. We aimed to identify patterns cannabis strongest effect on odds across Europe and explore differences in such contribute variations rates disorder.
The 'jumping to conclusions' (JTC) bias is associated with both psychosis and general cognition but their relationship unclear. In this study, we set out clarify the between JTC bias, IQ, polygenic liability schizophrenia IQ.A total of 817 first episode patients 1294 population-based controls completed assessments intelligence (IQ), JTC, provided blood or saliva samples from which extracted DNA computed risk scores for IQ schizophrenia.The estimated proportion effect case/control differences...
Abstract Background Schizophrenia (SZ), bipolar disorder (BD) and depression (D) run in families. This susceptibility is partly due to hundreds or thousands of common genetic variants, each conferring a fractional risk. The cumulative effects the associated variants can be summarised as polygenic risk score (PRS). Using data from EUropean Network national schizophrenia networks studying Gene-Environment Interactions (EU-GEI) first episode case–control study, we aimed test whether PRSs for...
Facial Emotion Recognition is a key domain of social cognition associated with psychotic disorders as candidate intermediate phenotype. In this study, we set out to investigate global and specific facial emotion recognition deficits in first-episode psychosis, whether polygenic liability recognition.828 First Episode Psychosis (FEP) patients 1308 population-based controls completed assessments the Degraded Affect Task (DFAR) subsample 524 FEP 899 provided blood or saliva samples from which...
During the first month of pregnancy, brain and spinal cord are formed through a process called neurulation. However, this can be altered by low serum levels folic acid, environmental factors, or genetic predispositions. In 2018, surveillance study in Botswana, country with high incidence human immunodeficiency virus (HIV) lacking mandatory food folate fortification programs, found that newborns whose mothers were taking dolutegravir (DTG) during trimester pregnancy had an increased risk...
To establish whether the risk of psychotic disorders in cannabis users changes with time following cessation using data from European Network National Networks studying Gene-Environment Interactions Schizophrenia (EU-GEI) case-control study. The EU-GEI study collected first episode psychosis patients and population controls across sites Europe Brazil between May 2010 April 2015. Adjusted logistic regressions were applied to examine odd case status changed: (1) (2) different use groups....
African American kidney transplant recipients generally exhibit poor long-term graft survival compared with other ethnic groups. The combination of sirolimus, tacrolimus, and corticosteroids has proven to be effective in reducing rejection episodes high-risk organ islet cell but not yet been tested a large number patients.The outcomes 56 adult, primary treated corticosteroids, tacrolimus targeted relatively low trough blood levels were those concurrent group 65 white patients steroids,...
Abstract Diagnostic categories do not completely reflect the heterogeneous expression of psychosis. Using data from EU-GEI study, we evaluated impact schizophrenia polygenic risk score (SZ-PRS) and patterns cannabis use on transdiagnostic We analysed first-episode psychosis patients (FEP) controls, generating dimensions psychotic symptoms experiences using item response bi-factor modelling. Linear regression was used to test associations between these SZ-PRS, as well combined effect SZ-PRS...
Abstract Background A history of childhood adversity is associated with psychotic disorder, an increase in risk according to the number exposures. However, it not known why only some exposed individuals go on develop psychosis. One possibility pre-existing polygenic vulnerability. Here, we investigated, largest sample first-episode psychosis (FEP) cases date, whether and high scores for schizophrenia (SZ-PRS) combine synergistically psychosis, over above effect each alone. Methods We...
Abstract Cluster studies identified a subgroup of patients with psychosis whose premorbid adjustment deteriorates before the onset, which may reflect variation in genetic influence. However, other reported complex relationship between distinctive patterns cannabis use and cognitive impairment that is worthy consideration. We examined whether: (1) social functioning (PSF) academic (PAF) childhood adolescence current intellectual quotient (IQ) define different clusters 802 first-episode (FEP)...