Judit Selma
A5028605450- Schizophrenia research and treatment
- Mental Health Research Topics
- Bipolar Disorder and Treatment
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Amyotrophic Lateral Sclerosis Research
- Dementia and Cognitive Impairment Research
- Birth, Development, and Health
- Genetics and Neurodevelopmental Disorders
- Mental Health and Psychiatry
- MicroRNA in disease regulation
- Epigenetics and DNA Methylation
- Intergenerational Family Dynamics and Caregiving
- Functional Brain Connectivity Studies
- Tryptophan and brain disorders
- Alzheimer's disease research and treatments
Hospital de Sant Pau
2022-2025
Biomedical Research Networking Center on Neurodegenerative Diseases
2025
Universitat Autònoma de Barcelona
2025
Hospital Clínic de Barcelona
2022
Centro de Investigación Biomédica en Red de Salud Mental
2022
University of the Basque Country
2022
Abstract Background and Hypothesis A pro-inflammatory phenotype has been related to psychotic disorders. The neutrophil-lymphocyte ratio (NLR) is an accessible biomarker that could be helpful characterize this systemic inflammation state. Study Design This study evaluated the NLR in a cohort of 310 subjects with first episode psychosis (FEP) matched group 215 healthy controls, recruited 16 Spanish centers participating PEPs Project. We investigated measures over 2 years prospective,...
Abstract INTRODUCTION Self‐reported sex influences brain resilience, but its role in genetic frontotemporal dementia (FTD) remains unclear. METHODS We analyzed 394 genetic‐FTD patients and 279 controls from the ALLFTD consortium, assessing annual neuropsychological performance MRI‐based cortical thickness. Clinical characteristics thickness were compared between sexes. used residuals of linear regression models, which predict each participant's cognitive behavioral levels relative to...
The main objective of the present study was to investigate association between several epigenetic clocks, covering different aspects aging, with schizophrenia relapse evaluated over a 3-year follow-up period in cohort ninety-one first-episode patients. Genome-wide DNA methylation profiled and four including clocks chronological age, mortality telomere length were calculated. Patients that relapsed during showed acceleration clock (p = 0.030). Shorter associated cognitive performance (working...
Emotional intelligence (EI) and neurocognition (NC) impairments are common in first-episode psychosis (FEP), yet their evolution over time remains unclear. This study identified patient profiles EI NC performance FEP. 98 adult FEP patients 128 healthy controls (HCs) were tested on clinical, functional, EI, variables at baseline two-year follow-up (FUP). A repeated-measures ANOVA compared the effects of group (patients HCs) EI. Significant improvements observed both groups. Four groups...
Abstract Background Accumulating evidence indicates that biological sex may influence clinical manifestation within the spectrum of frontotemporal lobar degeneration (FTLD), implying differences in cognitive reserve. Nonetheless, investigations into impact during preclinical and minimally symptomatic stages FTLD are lacking. Method We included 275 mutation carriers (158 females; 127 with C9orf72, 68 GRN, 80 MAPT mutations) 161 non‐carrier familial controls (97 females) from ALLFTD Consortium...
Approximately 30%-50% of people with schizophrenia worldwide have treatment-resistant (TRS). Currently available standard psychopharmacological and psychological treatments proven insufficient to achieve full recovery in these patients. Alternative interventions focused on improving emotion regulation, such as the Unified Protocol for Transdiagnostic Treatment Emotional Disorders (UP), could potentially improve treatment outcomes this difficult treat population. The aim present case study is...