- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Functional Brain Connectivity Studies
- Child and Adolescent Psychosocial and Emotional Development
- Advanced Neuroimaging Techniques and Applications
- Adolescent and Pediatric Healthcare
- Attention Deficit Hyperactivity Disorder
- Mental Health Research Topics
- Tryptophan and brain disorders
- Obsessive-Compulsive Spectrum Disorders
- Genetics and Neurodevelopmental Disorders
- Advanced MRI Techniques and Applications
- Maternal Mental Health During Pregnancy and Postpartum
- Epilepsy research and treatment
- Mental Health and Psychiatry
- Autism Spectrum Disorder Research
- Electroconvulsive Therapy Studies
- Birth, Development, and Health
- Genetic Associations and Epidemiology
- Human Health and Disease
- Neuroscience and Neuropharmacology Research
- Autoimmune Neurological Disorders and Treatments
- Pharmaceutical studies and practices
- Neural dynamics and brain function
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Universitat de Barcelona
2011-2024
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2015-2024
Centro de Investigación Biomédica en Red de Salud Mental
2017-2024
Hospital Clínic de Barcelona
2015-2024
Hospital Universitari de Vic
2022-2024
Fundació Clínic per a la Recerca Biomèdica
2021-2024
Instituto de Salud Carlos III
2023-2024
Hospital Sant Joan de Déu Barcelona
2020-2024
Fundació de Recerca Clínic Barcelona-Institut d’Investigacions Biomèdiques August Pi i Sunyer
2023-2024
Centro de Investigación Biomédica en Red
2019-2024
There is limited evidence on the effects of age and sex intrinsic connectivity networks underlying cognition during childhood adolescence. Independent component analysis was conducted in 113 subjects aged 7-18; default mode, executive control, anterior salience, basal ganglia, language visuospatial were identified. The effect examined with multiple regression, while 'age × sex' interactions assessed by dividing sample according to (7-12 13-18 years). As increased, dorsal ventral mode network...
To report the neuropsychiatric features and frequency of NMDA receptor (NMDAR) other neuronal immunoglobulin G antibodies in patients with first episode psychosis (FEP) to assess performance reported warning signs criteria for autoimmune (AP).This was a prospective observational study FEP assessed symptoms, serum CSF (brain immunohistochemistry, cell-based assays, live neurons), AP. Previous series were reviewed.One hundred five included; their median age 30 (range 14-75) years, 44 (42%)...
Abstract Introduction Regional gray matter (GM) alterations have been reported in early-onset psychosis (EOP, onset before age 18), but previous studies yielded conflicting results, likely due to small sample sizes and the different brain regions examined. In this study, we conducted a whole voxel-based morphometry (VBM) analysis large of individuals with EOP, using newly developed ENIGMA-VBM tool. Methods 15 independent cohorts from ENIGMA-EOP working group participated study. The overall...
Abstract Machine learning approaches using structural magnetic resonance imaging (sMRI) can be informative for disease classification, although their ability to predict psychosis is largely unknown. We created a model with individuals at CHR who developed later (CHR-PS+) from healthy controls (HCs) that differentiate each other. also evaluated whether we could distinguish CHR-PS+ those did not develop (CHR-PS-) and uncertain follow-up status (CHR-UNK). T1-weighted brain MRI scans 1165...
<h3>Objective</h3> To describe the sleep disorders in anti–NMDA receptor encephalitis (anti-NMDARe). <h3>Methods</h3> Patients recovering from anti-NMDARe were invited to participate a prospective observational single-center study including comprehensive clinical, video-polysomnography (V-PSG) assessment, and neuropsychological evaluation. Age- sex-matched healthy participants served as controls. <h3>Results</h3> Eighteen patients (89% female, median age 26 years, interquartile range [IQR]...
Article Abstract Objective: Despite the additional complications associated with alcohol misuse in bipolar populations, it is generally case that studies exploring neurocognitive aspects of disorder specifically exclude patients abuse or dependence. Given role cognitive dysfunctions overall illness outcome, this study addressed functioning a history dependence as compared to without such and healthy controls. Method: The sample included 100 subjects: 65 patients, 30 whom 35 previous...
Schizophrenia (SZ) and bipolar disorder (BD) share clinical features, genetic risk factors neuroimaging abnormalities. There is evidence of disrupted connectivity in resting state networks patients with SZ BD their unaffected relatives. Resting are known to undergo reorganization during youth coinciding the period increased incidence for both disorders. We therefore focused on characterizing network at familial or identify alterations arising this period. measured resting-state functional a...
Individuals at Clinical High Risk for Psychosis (CHR-P) demonstrate heterogeneity in clinical profiles and outcome features. However, the extent of neuroanatomical CHR-P state is largely undetermined. We aimed to quantify structural magnetic resonance imaging measures cortical surface area (SA), thickness (CT), subcortical volume (SV), intracranial (ICV) individuals compared with healthy controls (HC), relation subsequent transition a first episode psychosis. The ENIGMA consortium applied...
Schizophrenia and bipolar disorder exhibit substantial clinical overlap, particularly in individuals at familial high risk, who frequently present sub-threshold symptoms before the onset of illness. Severe mental disorders are highly polygenic traits, but their impact on stages preceding manifestation remains relatively unexplored. Our study aimed to examine influence risk scores (PRS) sub-clinical outcomes over a 2-year period youth for schizophrenia controls. The sample included 222...
Summary We aim to investigate whether temporal origin of epilepsy increases the risk developing a psychiatric disorder and more specifically major depressive disorder. The lack standardized diagnostic instruments methodologic differences between studies highlight fact that this issue warrants further, systematic, study. Three‐hundred eight patients with complex partial seizures were classified according or extratemporal origin, following Commission on Classification Terminology International...
Observational studies have reported earlier onset of psychosis in schizophrenic patients with a history cannabis use. Earlier age schizophrenia has been associated poorer outcome. We aimed to examine whether use determined an sample first episode patients, area one Europe's highest rates use.116 subjects and subsequent diagnosis (after 12-month follow-up) were included Age at antipsychotic treatment (A1T) was used as proxy for onset, acted dependent variable the statistical analysis....