Wenche ten Velden Hegelstad

ORCID: 0000-0003-1148-8825
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About
Contact & Profiles
Research Areas
  • Schizophrenia research and treatment
  • Mental Health and Psychiatry
  • Bipolar Disorder and Treatment
  • Mental Health Research Topics
  • Mental Health Treatment and Access
  • Child and Adolescent Psychosocial and Emotional Development
  • Psychosomatic Disorders and Their Treatments
  • Obsessive-Compulsive Spectrum Disorders
  • Functional Brain Connectivity Studies
  • Digital Mental Health Interventions
  • Child Abuse and Trauma
  • Mental Health and Patient Involvement
  • Advanced Neuroimaging Techniques and Applications
  • Neurotransmitter Receptor Influence on Behavior
  • Family Caregiving in Mental Illness
  • Family Support in Illness
  • Parkinson's Disease Mechanisms and Treatments
  • Psychotherapy Techniques and Applications
  • Psychiatric care and mental health services
  • COVID-19 and Mental Health
  • Family and Patient Care in Intensive Care Units
  • Attention Deficit Hyperactivity Disorder
  • Neuroscience and Music Perception
  • Tryptophan and brain disorders
  • Health disparities and outcomes

Stavanger University Hospital
2015-2024

University of Stavanger
2012-2024

State University System of Florida
2019

Psykiatrien i Region Syddanmark
2018

University of Bergen
2012-2016

University of Oslo
2012-2015

Oslo University Hospital
2012-2015

Diakonhjemmet Hospital
2015

Region Zealand
2012

Psychiatry Region Zealand
2012

Objective: Early detection in first-episode psychosis confers advantages for negative, cognitive, and depressive symptoms after 1, 2, 5 years, but longitudinal effects are unknown. The authors investigated the differences recovery 10 years between regional health care sectors with without a comprehensive program early of psychosis. Method: evaluated 281 patients (early detection, N=141) 18 to 65 old first episode nonaffective 1997 2001. Of these, 101 early-detection area 73 usual-detection...

10.1176/appi.ajp.2011.11030459 article EN American Journal of Psychiatry 2012-03-08

A substantial proportion of schizophrenia-spectrum patients exhibit a cognitive impairment at illness onset. However, the long-term course neurocognition and possible neurotoxic effect time spent in active psychosis, is topic controversy. Furthermore, it importance to find out what predicts neurocognition. Duration untreated psychosis (DUP), accumulated first year after start treatment, relapse rates symptoms are potential predictors course. In this study, 261 first-episode were assessed...

10.1093/schbul/sbv083 article EN Schizophrenia Bulletin 2015-06-21

Background: Social functioning is an important treatment outcome for psychosis, and yet, we know little about its relationship to trauma despite high rates of in people with psychosis. Childhood likely disrupt the acquisition interpersonal relatedness skills including desire affiliation thus lead impaired social adulthood. Aims: We hypothesized that childhood would be a predictor poor adults psychosis further adulthood moderate this relationship. Method: A first-episode sample aged 15–65...

10.1093/schbul/sbt166 article EN Schizophrenia Bulletin 2013-11-26

Substance use is common in first-episode psychosis (FEP) and has been linked to poorer outcomes with more severe psychopathology higher relapse rates. Early substance discontinuation appears improve symptoms function. However, studies vary widely their methodology, few have examined patients longitudinally, making it difficult draw conclusions for practice treatment. We aimed investigate the relationship between early abstinence long-term course of illness a representative sample FEP...

10.1093/schbul/sbw179 article EN Schizophrenia Bulletin 2016-11-25

Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and relationship to clinically significant subgroups even more so. We report 10 year longitudinal development a sample FEP patients, explore whether trajectories cognitive are related presence relapse psychosis, especially within year, with focus on verbal memory. Method: Forty-three subjects...

10.3389/fnhum.2013.00643 article EN cc-by Frontiers in Human Neuroscience 2013-01-01

Objective: Identifying patients at risk of poor outcome an early stage illness can aid in treatment planning. This study sought to create a best-fit statistical model known baseline and early-course factors predict time psychosis during ten-year follow-up period after first psychotic episode. Methods: Between 1997 2000, 301 with DSM-IV nonorganic, nonaffective first-episode were recruited consecutively from catchment area–based sectors Norway Denmark. Specialized mental health personnel...

10.1176/appi.ps.201400558 article EN Psychiatric Services 2015-11-16

Patients with schizophrenia spectrum disorders and substance use may have an earlier onset of illness compared to those without use. Most previous studies have, however, too small samples control for confounding variables the effect specific types substances. The present study aimed examine relationship between age at onset, in addition influence possible confounders substances, a large heterogeneous multisite sample patients disorders.The (N=1119) were recruited from catchment areas Oslo,...

10.1016/j.schres.2015.11.027 article EN cc-by-nc-nd Schizophrenia Research 2015-12-15
Helen Baldwin Joaquim Raduà Mathilde Antoniades Shalaila S. Haas Sophia Frangou and 95 more Ingrid Agartz Paul Allen Ole A. Andreassen Kimberley Atkinson Peter Bachman Inmaculada Baeza Cali F. Bartholomeusz Michael W.L. Chee Tiziano Colibazzi Rebecca Cooper Cheryl M. Corcoran Vanessa Cropley Bjørn H. Ebdrup Adriana Fortea Louise Birkedal Glenthøj Holly Hamilton Kristen M. Haut Rebecca A. Hayes Ying Hé Karsten Heekeren Michael Kaess Kiyoto Kasai Naoyuki Katagiri Minah Kim Jochen Kindler Mallory J. Klaunig Shinsuke Koike Alex Koppel Tina Dam Kristensen Yoo Bin Kwak Jun Soo Kwon Stephen M. Lawrie Irina Lebedeva Jimmy Lee Ashleigh Lin Rachel Loewy Daniel H. Mathalon Chantal Michel Romina Mizrahi Paul Møller Barnaby Nelson Takahiro Nemoto Dorte Nordholm M. A. Оmelchenkо Christos Pantelis Jayachandra M. Raghava Jan Ivar Røssberg Wulf Rössler Dean F. Salisbury Daiki Sasabayashi Ulrich Schall Lukasz Smigielski Gisela Sugranyes Michio Suzuki Tsutomu Takahashi Christian K. Tamnes Jinsong Tang Anastasia Theodoridou Sophia I. Thomopoulos Alexander S. Tomyshev Peter J. Uhlhaas Tor Gunnar Værnes Thérèse van Amelsvoort Theo G.M. van Erp James A. Waltz Lars T. Westlye Stephen J. Wood Juan Zhou Philip McGuire Paul M. Thompson Maria Jalbrzikowski Dennis Hernaus Paolo Fusar‐Poli Camilo de la Fuente‐Sandoval Sabrina Catalano Daniela Hubl Jason Schiffman Enea D. Venegoni Christine I. Hooker Paul E. Rasser Wenche ten Velden Hegelstad Franz Resch Imke Lemmers-Jansen G. Paul Amminger Xiaogang Chen Kang Ik K. Cho Birte Glenthøj Lieuwe de Haan Matthew A. Harris Wu Jeong Hwang Pablo León-Ortíz Xiaoqian Ma Patrick D. McGorry Ricardo Mora-Durán Masafumi Mizuno

Individuals at Clinical High Risk for Psychosis (CHR-P) demonstrate heterogeneity in clinical profiles and outcome features. However, the extent of neuroanatomical CHR-P state is largely undetermined. We aimed to quantify structural magnetic resonance imaging measures cortical surface area (SA), thickness (CT), subcortical volume (SV), intracranial (ICV) individuals compared with healthy controls (HC), relation subsequent transition a first episode psychosis. The ENIGMA consortium applied...

10.1038/s41398-022-02057-y article EN cc-by Translational Psychiatry 2022-07-26

Abstract Aims The present study examined if any patient characteristics at baseline predicted depressive symptoms 10 years and whether patients prone to in the first year of treatment had a different prognosis following years. Method A total 299 first‐episode psychosis ( FEP ) with schizophrenia spectrum disorders were assessed for PANSS depression item (g6) baseline, 1, 2, 5 follow up. At years, also C algary D epression Scale S chizophrenia (CDSS). g6 ≥ 4 CDSS score 6 used as cut‐off...

10.1111/eip.12163 article EN Early Intervention in Psychiatry 2014-06-23

Abstract Introduction The COVID‐19 pandemic affects people globally, but it may affect with psychotic and bipolar disorders disproportionally. Our aims were to investigate the impact on perceived wellbeing mental health in this population, including which pandemic‐related factors have had an impact. Methods People ( N = 520; female 81%; n 75/bipolar disorder 445) completed online survey about early phase of (June 5–July 5, 2020). Results Many participants experienced deteriorated after...

10.1002/brb3.2559 article EN Brain and Behavior 2022-04-06

Abstract Background Qualitative research frequently characterises recovery, but more knowledge on subjective experiences of facilitators long-term recovery in psychosis is needed. This interview study aimed to explore what people with first-episode (FEP) highlight as important for their recovery. Methods Interviews 20 individuals (personal and/or clinical) participating two follow-up studies, 10 and 20-years after treatment start a first episode schizophrenia or bipolar spectrum disorder....

10.1186/s12888-025-06681-y article EN cc-by BMC Psychiatry 2025-04-28

Background Hallucinations are a core diagnostic criterion for psychotic disorders and have been investigated with regard to its association childhood trauma in first-episode psychosis samples. Research has largely focused on auditory hallucinations, while specific investigations of visual hallucinations remain scarce. Objectives The aims this study were describe the prevalence explore between hallucination sample. Methods Subjects included from TIPS-2, first episode south Rogaland, Norway....

10.1371/journal.pone.0153458 article EN cc-by PLoS ONE 2016-05-04

Substance misuse is a well-recognized co-morbidity to psychosis and has been linked poor prognostic outcomes in patients. Researchers have yet investigate the difference rates characteristics between first-episode Induced Psychosis (SIP) primary psychosis. We aimed at comparing patients with SIP or without substance baseline. Thirty patients, 45 (PS) 66 (PNS) well-defined Norwegian catchment area were included from 2007–2011. Assessments symptom levels (PANSS), diagnostic interviews (SCID),...

10.1186/1471-244x-13-319 article EN cc-by BMC Psychiatry 2013-11-27
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