A5077610201- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Advanced Neuroimaging Techniques and Applications
- Neural dynamics and brain function
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neuroscience and Music Perception
- EEG and Brain-Computer Interfaces
- Obsessive-Compulsive Spectrum Disorders
- Neural and Behavioral Psychology Studies
- Mental Health Research Topics
- Mindfulness and Compassion Interventions
- Advanced MRI Techniques and Applications
- Impact of Technology on Adolescents
- Transcranial Magnetic Stimulation Studies
- Child Development and Digital Technology
- Stress Responses and Cortisol
- Psychosomatic Disorders and Their Treatments
- Bipolar Disorder and Treatment
- Fetal and Pediatric Neurological Disorders
- Tryptophan and brain disorders
- Health, Environment, Cognitive Aging
- Gastrointestinal motility and disorders
- Menopause: Health Impacts and Treatments
- Ion channel regulation and function
- Hallucinations in medical conditions
Seoul National University
2016-2023
Catholic Kwandong University
2023
Institute for Basic Science
2020
National University College
2020
New Generation University College
2020
Florey Institute of Neuroscience and Mental Health
2018
The University of Melbourne
2018
While recent studies have explored the maintenance of effect meditation on stress resilience, underlying neural mechanisms not yet been investigated. The present study conducted a highly controlled residential 4-day intervention to investigate brain functional changes and long-term effects mindfulness resilience. Thirty participants in practice 17 relaxation retreat (control group) underwent magnetic resonance imaging scans at baseline post-intervention completed Cognitive Affective...
Individuals at Clinical High Risk for Psychosis (CHR-P) demonstrate heterogeneity in clinical profiles and outcome features. However, the extent of neuroanatomical CHR-P state is largely undetermined. We aimed to quantify structural magnetic resonance imaging measures cortical surface area (SA), thickness (CT), subcortical volume (SV), intracranial (ICV) individuals compared with healthy controls (HC), relation subsequent transition a first episode psychosis. The ENIGMA consortium applied...
Although internet gaming disorder (IGD) and obsessive-compulsive (OCD) represent opposite ends of the impulsivity compulsivity dimensions, two disorders share common neurocognitive deficits in response inhibition. However, similarities differences neurophysiological features altered inhibition between IGD OCD have not been investigated sufficiently. In total, 27 patients with IGD, 24 OCD, 26 healthy control (HC) subjects participated a Go/NoGo task electroencephalographic recordings. N2-P3...
The interest in mindfulness meditation interventions has surged due to their beneficial effects fostering resilience and reducing stress both clinical non-clinical populations. However, the relaxation benefits that may occur while practicing long-term of these remain unclear. Fifty-one participants were recruited randomized into experimental control groups, which underwent 4 days Intensive Meditation (Templestay program, n = 33) Relaxation (Control, 18), respectively. self-report measures...
While recent studies have suggested behavioral effects of short-term meditation on the executive attentional functions, functional changes in neural correlates networks after been unspecified. Here, we conducted a randomized control trial to investigate four-day intensive three functions: alerting, orienting, and attention. Twenty-three participants practice 14 relaxation retreat group performed attention network test (ANT) during magnetic resonance imaging both before immediately...
Abstract Background Over the past two decades, early detection and intervention in psychosis have become essential goals of psychiatry. However, clinical impressions are insufficient for predicting outcomes high-risk (CHR) individuals; a more rigorous objective model is needed. This study aims to develop internally validate transition within 10 years. Methods Two hundred eight help-seeking individuals who fulfilled CHR criteria were enrolled from prospective, naturalistic cohort program at...
Objective: Numerous reports on neurocognitive functioning deficits in individuals at clinical high risk (CHR) and first-episode psychosis (FEP) patients suggest particular executive (EF). However, to date, most of the studies have administered a single or few EF tests participants, investigations examined different components identify specific subdomains relative strength weakness. Method: Forty CHR subjects, 85 FEP healthy controls (HC) were assessed with neuropsychological battery...
Emotion dysregulation is crucial to both poor social functioning and psychotic symptom formation in patients with schizophrenia. The efficient use of emotion regulation strategies, such as cognitive reappraisal, has been less frequently observed the early phases disorder. It unknown whether neurophysiological responses related by reappraisal are altered psychosis.Fifty-four first-episode psychosis (FEP), 34 subjects at clinical high risk (CHR) for psychosis, 30 healthy controls (HCs)...
Background: Although mismatch negativity (MMN) is associated with the pathophysiology of schizophrenia, whether MMN progressively worsens during initial years psychotic disorder has not yet been sufficiently studied. We aimed to investigate longitudinal reduction occurs in patients first-episode psychosis (FEP) and it reflective change cognitive functioning or clinical status. Methods: status 25 FEP were measured Trail Making Test (TMT) was administered at baseline reassessed after 1 year...
Abnormal thalamocortical networks involving specific thalamic nuclei have been implicated in schizophrenia pathophysiology. While comparable topography of anatomical and functional connectivity abnormalities has reported patients across illness stages, previous studies confined to pathways networks. To address this issue, we incorporated large-scale brain network dynamics into examining connectivity. Forty with first-episode psychosis forty healthy controls underwent T1-weighted...
The lack of robust neuroanatomical markers psychosis risk has been traditionally attributed to heterogeneity. A complementary hypothesis is that variation in measures the majority individuals at may be nested within range observed healthy individuals.
Deficits in theory of mind (ToM) are considered as a distinctive feature schizophrenia. Functional magnetic resonance imaging (fMRI) studies have suggested that aberrant activity among the regions comprising mentalizing network is related to observed ToM deficits. However, white matter structures underlying functional schizophrenia remain unclear. To investigate relationship between integrity and impairment, 35 patients with first-episode psychosis (FEP) 29 matched healthy controls (HCs)...
Abstract Although abnormal cortical gyrification has been consistently reported in patients with schizophrenia, whether abnormalities reflect a genetic risk for the disorder remains unknown. This study investigated differences between unaffected relatives (URs) high loading schizophrenia and healthy controls (HCs) to identify potential vulnerability markers. A total of 50 URs matched HCs underwent T1-weighted magnetic resonance imaging compare whole-brain using local index (lGI). Then, lGI...
Obsessive-compulsive disorder (OCD) and internet gaming (IGD), which are similar in that both involve repetitive behaviors related with cognitive dysfunctions, frequently begin early adolescence, is a critical period for learning. Although the deterioration functioning caused by these conditions may have adverse effects on information processing, such as text reading, there has been no comprehensive research objective indicators of altered reading patterns patients. Therefore, we evaluated...
Although previous studies have reported impaired performance in the reading mind eyes test (RMET), which measures complex emotion recognition abilities, patients with schizophrenia, reports regarding individuals at clinical high risk (CHR) for psychosis been inconsistent, mainly due to interacting confounding effects of general cognitive abilities and age. We compared RMET performances across first-episode (FEP) patients, CHR individuals, healthy controls (HCs) while controlling both age.A...
Background. The reduced amplitude, prolonged latency, and increased intertrial variability of auditory P300 have been consistently reported in relation to the symptomatic severity schizophrenia. This study investigated whether event-related potentials can be used as an objective indicator improvement by transcranial direct current stimulation (tDCS) patients with Methods. Ten schizophrenia received 20 minutes 2-mA tDCS twice a day for 5 consecutive weekdays. anode was placed over left...
Abstract Background Prognostic heterogeneity in early psychosis patients yields significant difficulties determining the degree and duration of intervention; this highlights need for prognostic biomarkers. Although mismatch negativity (MMN) has been widely studied across phases psychotic disorders, its potential as a common biomarker periods, such clinical high risk (CHR) first-episode (FEP), not fully studied. Methods A total 104 FEP patients, 102 CHR individuals, 107 healthy controls (HCs)...