A5061830368- Schizophrenia research and treatment
- Functional Brain Connectivity Studies
- Tryptophan and brain disorders
- Education, Healthcare and Sociology Research
- Bipolar Disorder and Treatment
- Mental Health and Psychiatry
- Treatment of Major Depression
- Psychosomatic Disorders and Their Treatments
- Social and Educational Sciences
- European and International Law Studies
- Neuroscience and Music Perception
- Complex Systems and Decision Making
- Electroconvulsive Therapy Studies
- Stress Responses and Cortisol
- Neuroscience and Neuropharmacology Research
- Child and Adolescent Psychosocial and Emotional Development
- Advanced Neuroimaging Techniques and Applications
- Child Abuse and Trauma
- Business Strategy and Innovation
- Hallucinations in medical conditions
- Neurotransmitter Receptor Influence on Behavior
- Research in Social Sciences
- Mental Health Research Topics
- Mental Health Treatment and Access
- Psychiatric care and mental health services
University of Bergen
2016-2025
Haukeland University Hospital
2016-2025
Oslo University Hospital
2013-2025
Innsbruck Medical University
2023
University of Stavanger
2023
Stavanger University Hospital
2023
St Olav's University Hospital
2023
Norwegian University of Science and Technology
2012-2023
University of Oslo
2017-2020
Warneford Hospital
2020
Surveys on prescription patterns for antipsychotics in the Scandinavian public health system are scarce despite prevalent use of these drugs. The clinical differences between antipsychotic drugs mainly areas safety and tolerability, international guidelines treatment schizophrenia offer rational strategies to minimize burden side effects related treatment. implementation practice have proven difficult achieve, as reflected by major variations different comparable regions countries. objective...
Abstract Background: Assessment of suicide risk is crucial in schizophrenia and results concerning contributed by hallucinations persecutory delusions are inconsistent. We aimed to determine factors associated with suicidal ideation plans at the time acute admission patients suffering from spectrum disorders. Methods: One hundred twenty-four older than 18 years admitted an psychiatric ward due psychosis were consecutively included. Predictors examined multinominal logistic regression...
ORIGINAL RESEARCH article Front. Hum. Neurosci., 24 April 2013Sec. Speech and Language Volume 7 - 2013 | https://doi.org/10.3389/fnhum.2013.00144
Cognitive impairment is a core feature of schizophrenia, which predictive for functional outcomes and is, therefore, treatment target in itself. Yet, literature on efficacy different pharmaco-therapeutic options inconsistent. This quantitative review provides an overview studies that investigated potential cognitive enhancers schizophrenia. We included pharmacological agents, neurotransmitter systems evaluated their overall functioning seven separate domains. In total, 93 with 5630 patients...
Inflammatory processes have been implicated in the etiology of schizophrenia and related psychoses, which cognitive deficits represent core symptoms. The aim present study was to investigate possible associations between level inflammation marker C-reactive protein (CRP) performance patients through acute phase psychosis. A total 124 were assessed at admittance hospital 62 retested discharge or after 6 weeks latest, with measurements CRP levels alternative forms Repeatable Battery for...
Abstract Current guidelines for patients with schizophrenia spectrum disease do not take sex differences into account, which may result in inappropriate sex-specific treatment. In the BeSt InTro study, a total of 144 (93 men and 51 women) diagnosis ongoing psychosis were included randomized to amisulpride, aripiprazole, or olanzapine flexible dose. This trial is registered ClinicalTrials.gov (NCT01446328). Primary outcomes dose, dose-corrected serum levels, efficacy, tolerability. Dosing was...
Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that part of a psychosis continuum, dysregulated innate immune responses have been suggested to be involved in their pathophysiology. However, disease-specific mechanisms SMI not known yet. Recently, dyslipidemia has linked systemic inflammasome activation, elevated atherogenic lipid ratios shown correlate with circulating levels inflammatory biomarkers SMI. It is, however, yet if increased cholesterol load leads...
Schizophrenia is characterized by impaired cognitive functioning, and brain regions involved in control processes show marked glutamatergic abnormalities. However, it presently unclear whether aberrant neuronal response directly related to the observed deficits at metabolite level schizophrenia. Here, 17 medicated schizophrenia patients matched healthy participants underwent functional magnetic resonance imaging (fMRI) when performing an auditory task, as well proton spectroscopy (1H-MRS)...
Patients with schizophrenia spectrum disorders and substance use may have an earlier onset of illness compared to those without use. Most previous studies have, however, too small samples control for confounding variables the effect specific types substances. The present study aimed examine relationship between age at onset, in addition influence possible confounders substances, a large heterogeneous multisite sample patients disorders.The (N=1119) were recruited from catchment areas Oslo,...
Aims The aim of this study was to investigate time trends in dosing and prevalence antipsychotic prescriptions Scandinavia. Methods We retrieved data on use between 2006 2016 from Danish, Norwegian Swedish national prescription registers. For each antipsychotic, we calculated mean doses, overall for specific age groups (young, adults elderly). Results Antipsychotic Scandinavia increased 16.5 17.2 users/1000 inhabitants (+2.4%, annual change: 0.07 inhabitants/year, 95% CI: 0.02–0.20, P =...
There is a wealth of evidence showing aberrant functional connectivity (FC) in schizophrenia but with considerable variability findings across studies. Dynamic FC an extension traditional static FC, that such analyses allow for explorations temporal changes connectivity. Thereby they also provide more detailed information on abnormalities psychiatric disorders as schizophrenia. The current study investigated dynamic sample 80 patients and matched healthy control subjects, replicating...