Claudia Morales

ORCID: 0000-0002-8650-8811
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About
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Research Areas
  • Nonmelanoma Skin Cancer Studies
  • Cutaneous Melanoma Detection and Management
  • Cancer and Skin Lesions
  • Cutaneous lymphoproliferative disorders research
  • Nail Diseases and Treatments
  • Genetic and rare skin diseases.
  • Lymphoma Diagnosis and Treatment
  • Autoimmune and Inflammatory Disorders
  • Vascular Tumors and Angiosarcomas
  • Autoimmune Bullous Skin Diseases
  • Vascular Malformations and Hemangiomas
  • melanin and skin pigmentation
  • Sarcoma Diagnosis and Treatment
  • Dermatological and Skeletal Disorders
  • Urologic and reproductive health conditions
  • Skin and Cellular Biology Research
  • Tumors and Oncological Cases
  • Hidradenitis Suppurativa and Treatments
  • Medicine and Dermatology Studies History
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Colorectal and Anal Carcinomas
  • Sports injuries and prevention
  • Psoriasis: Treatment and Pathogenesis
  • Exercise and Physiological Responses
  • Hedgehog Signaling Pathway Studies

University of Chile
2011-2024

Hospital Clínico de la Universidad de Chile
2013-2023

Universidad Mayor
2019

University of Valparaíso
2005

Objectives To explore the capability of very high‐frequency ultrasound (US; 50–71 MHz) to detect normal morphologic characteristics hair follicles and tracts, sebaceous glands, Montgomery apocrine arrector pili muscles. Methods A retrospective study, approved by Institutional Review Board, evaluated US adnexal structures in a database images extracted from perilesional or contralateral healthy skin 1117 consecutive patients who underwent examinations for localized lesions 10 individuals...

10.1002/jum.14888 article EN Journal of Ultrasound in Medicine 2018-12-20

Una de las problemáticas con que se encuentra el o la docente Ciencias Físicas, es falta motivación presenta estudiantado. El uso TICS, como herramientas del proceso aprendizaje, permite obtener beneficios asociados a dicha problemática, ya actúan agente motivacional y facilitador participación. En este trabajo utilizó herramienta tecnológica Tracker, modelar fenómenos físicos través análisis videos mecánicos. Se diseñan actividades aprendizaje basadas en un modelo socio-constructivista,...

10.46932/sfjdv6n1-024 article ES South Florida Journal of Development 2025-01-28

Objectives To compare the sonographic characteristics of pilonidal cysts and hidradenitis suppurativa. Methods A retrospective study examinations was performed on 2 groups: 1 with other The cyst suppurativa groups were analyzed, compared, correlated, including an analysis histologic findings. For group, distribution, morphologic characteristics, location, shape, diameter, axis, vascularity, scarring also described. Statistical analyses included Spearman, Wilcoxon, Kruskall‐Wallis, χ , Fisher...

10.1002/jum.14282 article EN Journal of Ultrasound in Medicine 2017-06-26

Autoimmune pancreatitis (AIP) can be chronic or recurrent, but frequently completely reversible after steroid treatment. A cystic lesion in AIP is a rare finding, and it mimic pancreatic neoplasm. Difficulties an exact diagnosis interfere with treatment, surgery cannot avoided some cases. We report the history of 63-year-old male presenting jaundice pruritus. was confirmed by imaging elevated IgG4 blood levels, patient recovered corticosteroid therapy. One year later, he presented recurrent...

10.1159/000441998 article EN cc-by-nc Case Reports in Gastroenterology 2015-11-23

In response to topical application of irritants, increased concentrations prostaglandin E2 (PGE2) are found in human skin exudate and cultured dermal fibroblasts. this study, PGE2 generated transdermal delivery irritant drug compounds was monitored hairless guinea pig (HGP) by a non-invasive method, reverse iontophoresis. Reverse iontophoresis is the movement molecules from under influence an applied electric field. Irritant were with (electrotransport), radioimmunoassay (RIA) after...

10.1111/j.1600-0625.1997.tb00176.x article EN Experimental Dermatology 1997-12-01

Granulomatous pigmented purpuric dermatosis clinically manifests as hyperpigmented maculae and petechiae, predominantly on the lower extremities. Histopathologically, it is characterized by a lymphocytic infiltrate in upper dermis, extravasated erythrocytes, hemosiderin deposits. There an infrequent variant called granulomatous dermatosis, which histologically presence of non-necrotizing granulomas associated with classic findings other dermatoses. It more frequently affects middle-aged...

10.1016/j.abd.2019.09.002 article EN cc-by Anais Brasileiros de Dermatologia 2019-09-01

We report the case of a 56-year old male with severe plaque psoriasis that was successfully treated ixekizumab, new anti interleukin (IL)-17 monoclonal antibody. During first months treatment he developed lentiginous eruption in sites rapidly resolving plaques. Biopsy and immunohistochemistry reports showed elements both lentigo post-inflammatory hyper pigmentation. These findings, which have been increasingly described anti-tumor necrosis factor alpha (TNFα) IL-12/IL-23 therapy, may be...

10.4081/dr.2017.7079 article EN cc-by-nc Dermatology Reports 2017-10-11

Basal cell carcinoma (BCC) is a common malignant tumor and its incidence has risen in recent decades. Research shown the relationship between ultraviolet (UV) radiation, skin immune system, BCC. The role of Langerhans cells (LC) response to tumors prompted research into LC density morphology UV radiation However, data are inconsistent due differences methodology. To study LCs peritumoral epidermis BCC using immunohistochemistry image processing software compare results with those from...

10.1016/s1578-2190(09)70152-0 article ES cc-by-nc-nd Actas Dermo-Sifiliográficas 2009-10-01

Pancreatic anaplastic carcinoma (PAC) is a rare entity (2-7% of pancreatic carcinomas), with mean survival 5.7 months. We present the case 44-year-old patient who consulted for upper gastroin-testinal bleeding and was admitted hemodynamically unstable. CT showed large mass in gastric fundus infiltration to pancreas, suggestive GIST. Esophagogastroduodenoscopy identified submucosal ulcerated lesion that intractable by this means. An emergency surgical resection performed, histology confirmed...

10.4067/s0034-98872024001001092 article EN PubMed 2024-10-01

Psoriasis has been associated with various autoimmune diseases, however, its relation to bullous diseases is infrequent. Of these, pemphigoid appears as the main entity, even though both conditions differ considerably in demographic and clinical aspects. We report case of a 42-year-old female patient, long-standing psoriasis who consulted due exacerbation psoriatic plaques generalized lesions on skin oral mucosa, one-week duration. With signs histopathological findings compatible psoriasis,...

10.1590/abd1806-4841.20198032 article EN cc-by Anais Brasileiros de Dermatologia 2019-05-08
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