- Cardiovascular Conditions and Treatments
- Gallbladder and Bile Duct Disorders
- Peptidase Inhibition and Analysis
- Veterinary Oncology Research
- Pediatric Hepatobiliary Diseases and Treatments
- Neuropeptides and Animal Physiology
- Infectious Diseases and Mycology
- Diabetes Treatment and Management
- Antifungal resistance and susceptibility
- Clinical Laboratory Practices and Quality Control
- Cardiac Valve Diseases and Treatments
- Congenital Ear and Nasal Anomalies
- Bipolar Disorder and Treatment
- Animal Nutrition and Physiology
- Pineapple and bromelain studies
- Congenital Anomalies and Fetal Surgery
- Research on Leishmaniasis Studies
- Renal Diseases and Glomerulopathies
- Hepatitis Viruses Studies and Epidemiology
- Trypanosoma species research and implications
- Fungal Infections and Studies
- Sinusitis and nasal conditions
- Viral Infections and Immunology Research
- Poxvirus research and outbreaks
- Salivary Gland Disorders and Functions
Farm Africa
2021
University College Dublin
2012-2019
Novartis (Switzerland)
2018
Novartis Institutes for BioMedical Research
2018
Royal Veterinary College
2018
Willows Veterinary Centre and Referral Service
2017
University of Bologna
2011
University of Milan
2008
Background Hypertrophic cardiomyopathy is the most prevalent heart disorder in cats and principal cause of cardiovascular morbidity mortality. Yet, impact preclinical disease unresolved. Hypothesis/Objectives Observational study to characterize survival with nonobstructive (HCM) obstructive (HOCM) hypertrophic apparently healthy (AH). Animals One thousand seven hundred thirty client‐owned (430 HCM; 578 HOCM; 722 AH). Methods Retrospective multicenter, longitudinal, cohort study. Cats from 21...
Background Bacterial cholangitis and cholecystitis are rarely reported, poorly characterized diseases in the dog. Objectives To characterize clinical features of these conditions. Animals Twenty‐seven client‐owned dogs with bacterial cholangitis, cholecystitis, or both. Methods Multicenter, retrospective cases series both, presenting January 2000 to June 2011 4 Veterinary Schools Ireland/ United Kingdom . Interrogation hospital databases identified all inclusion criteria; histopathologically...
A 9-month-old entire male domestic longhair indoor cat presented with a 3-week history of fluctuating fever, weight loss and small intestine diarrhoea, which was unresponsive to antibiotics supportive treatment. Abdominal ultrasound revealed severe jejunal ileocolic junction intestinal wall thickening layering. An enterectomy performed histopathology pyogranulomatous enteritis vasculitits, compatible the diagnosis feline infectious peritonitis (FIP). Four days after surgery, re-presented...
Epidemiologic knowledge regarding noncardiovascular and all-cause mortality in apparently healthy cats (AH) with preclinical hypertrophic cardiomyopathy (pHCM) is limited, hindering development of evidence-based healthcare guidelines.
Background In congestive heart failure ( HF ), plasma B‐type natriuretic peptide BNP ) seems devoid of biological effectiveness. 1–32 could be truncated into 3–32 by dipeptidyl peptidase IV DPP 4), and has reduced activities. Hypothesis Increased 4 activity is associated with pathophysiology . Animals One hundred twenty‐eight client‐owned dogs 9 experimental Beagles from the C linical V eterinary U nit niversity L iège. Methods We prospectively measured in 5 groups dogs: normal growing (n =...
To describe the diagnostic tests used and their comparative performance in dogs diagnosed with sinonasal aspergillosis United Kingdom. A secondary objective was to signalment, clinical findings common clinicopathologic abnormalities aspergillosis.
Objectives To evaluate if lithium heparin ( LiH ) and potassium ethylenediaminetetraacetic acid EDTA can be used interchangeably to obtain packed cell volume PCV total protein by refractometry TPr ), compare those values with laboratorywderived haematocrit (Hct) TP concentration, respectively, in canine blood samples. Methods Blood samples taken were manually assessed for . Results correlated Hct 238 corresponding serum/ obtained. There was excellent correlation but statistically significant...
Case summary A 13-year-old, castrated male, British Shorthair cat presented for investigation of chronic, intermittent, bilateral epistaxis and stertor. CT revealed severe asymmetric intranasal involvement with extensive turbinate lysis, increased soft tissue attenuation lysis the sphenopalatine bone cribriform plate. On retroflexed pharyngoscopy, a plaque-like mass occluded choanae. Rostral rhinoscopic examination loss nasal turbinates, necrotic mucosal fungal plaques in left cavity. The...
Objectives To report the available histology, biochemistry and clinical progression of dogs without classic overt biliary tract signs that underwent cholecystectomy for nongravity‐dependent sludge. Materials Methods Case series client‐owned which a was performed In six dogs, sludge filled less than half gall bladder volume, ejection fractions were measured. Available biochemistry, presenting post‐surgical reported. Results Sixteen included in this retrospective case series. No met...
An 8-year-old female spayed Siamese indoor cat presented with a 3 week history of inspiratory dyspnoea, stridor and open-mouth breathing after exercise. Laryngoscopy, tracheoscopy, bronchoscopy retroflexed nasopharyngoscopy were performed, identified multilobulated intraluminal mass within the trachea. Brush cytology was performed on but inconclusive in providing definitive diagnosis. A CT scan neck failed to identify an obvious negative contrast uptake. Surgery seven rings trachea removed...
A 12-year-old castrated male domestic shorthair cat was referred for investigation of lethargy, hindlimb weakness with plantigrade stance and ventroflexion the neck. The fed a balanced diet had received methylprednisolone acetate at dose 20 mg intramuscularly every 6 months years. On blood work, severe hypokalaemia marked elevation muscle enzymes were noticeable. findings suggestive hypokalaemic myopathy. Urine fractional excretion potassium (FE
To determine if gall bladder dysmotility occurs in dogs investigated for chronic altered appetite and to warrants further investigation as a contributing factor appetite.Case series of gastrointestinal disease. Gastrointestinal clinical signs were assessed before after 6-week hydrolysed protein diet. Gall ejection fractions determined at the end diet part an that included full blood cell count, biochemistry, abdominal X-rays ultrasound. The ejections fraction results with normal compared...
This case series discusses novel characteristics identified in two cases of cowpox. One presented with upper airway signs, and was to have a focal laryngeal lesion. The other had central neurological signs at the terminal stages, intracytoplasmic inclusion bodies within cerebral hemispheres on histopathology.Currently, cowpox would be an unlikely consideration patients or respiratory noise. These both document presentations infection, which clinicians should aware consider as differential...
An eight‐year‐old neutered female Golden Retriever presented for evaluation of lethargy, coughing, haemoptysis and pyrexia. Thoracic radiography identified a diffuse nodular pattern affecting all lung lobes echocardiography revealed hyperechoic intraluminal mass within the pulmonary artery. Postmortem examination confirmed presence small irregular raised non‐occluding sessile infiltrating wall It was composed plump spindle shaped or polygonal cells interspersed between occasionally lining...
e il 2003, su un gruppo di 34 pazienti (43 campioni) con sospetta infezione acuta.Tutti i campioni sono stati analizzati per IgM anti-HBc nuovo metodo Architect, che prevede una soglia positività a valore S/CO 1 "zona grigia" tra 0,5 1. Sono confrontati sia risultati qualitativi valori semiquantitativi (S/CO Architect Index AxSYM).Risultati.Tutti ottenuti dai epatite acuta o B positivi entrambi test anti-HBc, ma segnale era molto più intenso (media nei due gruppi: 21,0 25,2) AxSYM Index:...
e il 2003, su un gruppo di 34 pazienti (43 campioni) con sospetta infezione acuta.Tutti i campioni sono stati analizzati per IgM anti-HBc nuovo metodo Architect, che prevede una soglia positività a valore S/CO 1 "zona grigia" tra 0,5 1. Sono confrontati sia risultati qualitativi valori semiquantitativi (S/CO Architect Index AxSYM).Risultati.Tutti ottenuti dai epatite acuta o B positivi entrambi test anti-HBc, ma segnale era molto più intenso (media nei due gruppi: 21,0 25,2) AxSYM Index:...