A5071551314- Cardiovascular Conditions and Treatments
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Effects of Exercise
- Cardiac tumors and thrombi
- Congenital Heart Disease Studies
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Pericarditis and Cardiac Tamponade
- Infective Endocarditis Diagnosis and Management
- Ultrasound in Clinical Applications
- Veterinary Pharmacology and Anesthesia
- Cardiovascular Disease and Adiposity
- Veterinary Equine Medical Research
- Pulmonary Hypertension Research and Treatments
- Veterinary Oncology Research
- Cardiomyopathy and Myosin Studies
- Pharmacological Effects and Assays
- Cardiac Valve Diseases and Treatments
- Myasthenia Gravis and Thymoma
- Heart Rate Variability and Autonomic Control
- Parasitic Diseases Research and Treatment
- Phonocardiography and Auscultation Techniques
- Hemodynamic Monitoring and Therapy
- Ear and Head Tumors
Iowa State University
2010-2022
American College of Veterinary Internal Medicine
1999
Drake University
1996
The Ohio State University
1984-1991
University of Iowa
1990
Background Hypertrophic cardiomyopathy is the most prevalent heart disorder in cats and principal cause of cardiovascular morbidity mortality. Yet, impact preclinical disease unresolved. Hypothesis/Objectives Observational study to characterize survival with nonobstructive (HCM) obstructive (HOCM) hypertrophic apparently healthy (AH). Animals One thousand seven hundred thirty client‐owned (430 HCM; 578 HOCM; 722 AH). Methods Retrospective multicenter, longitudinal, cohort study. Cats from 21...
A Veterinary Medical Database search from 1982 to 1995 identified 1,383 dogs with tumors of the heart a total population 729,265 (0.19% incidence). Hemangiosarcoma (HSA) was most common cardiac tumor identified. In subset specific histologic diagnoses, number HSA almost 10‐fold that 2nd tumor, aortic body tumor. Primary were more than metastases. When biologic behavior noted, classified as malignant. Cardiac (excluding lymphoma) occurred often in between ages 7 and 15 years. very old (>15...
A Veterinary Medical Database search from 1982 to 1995 identified 1,383 dogs with tumors of the heart a total population 729,265 (0.19% incidence). Hemangiosarcoma (HSA) was most common cardiac tumor identified. In subset specific histologic diagnoses, number HSA almost 10-fold that 2nd tumor, aortic body tumor. Primary were more than metastases. When biologic behavior noted, classified as malignant. Cardiac (excluding lymphoma) occurred often in between ages 7 and 15 years. very old (>15...
Background The diagnosis of congestive heart failure (CHF) in cats is challenging. Point‐of‐care (POC) thoracic ultrasound and NT‐proBNP testing are emerging tools that may aid diagnosis. Hypothesis/Objectives To assess the diagnostic accuracy POC lung (LUS), focused cardiac (FCU), predicting a final CHF. Animals Fifty‐one respiratory distress. Methods Blood NT‐proBNP, LUS, FCU evaluating left atrial (LA) size presence pericardial effusion (PCEFF) were performed all cats. Lung findings...
Replacing the enzyme α- l -iduronidase at birth ameliorates symptoms in brain and periphery of dogs with mucopolysaccharidosis type I.
To characterize lung ultrasonography (LUS) findings in dogs with a primary clinical complaint of cough.100 client-owned coughing dogs.A standardized LUS examination was performed for all to quantify the number B lines and identify subpleural abnormalities at 4 sites on each hemithorax. The final diagnosis (reference standard) determined by medical record review, sensitivity specificity selected causes cough determined.Common underlying included dynamic airway collapse (n = 37), cardiogenic...
Activity of the circulating renin-angiotensin-aldosterone system (RAAS) has not been comprehensively characterized in cats with systemic hypertension (SH) or cardiomyopathy (CM), and effects furosemide amlodipine treatment on RAAS have fully evaluated cats.To document activity SH CM compared to healthy determine how profiles change treatment.Sixty-six client-owned cats: 15 (7 amlodipine-treated, 8 untreated), 17 advanced furosemide-treated, 10 furosemide-treated), 34 cats.Equilibrium...
Ractopamine, a synthetic β(2)-adrenoceptor agonist, is widely used as feed additive in the United States to promote reduction body fat and enhance muscle growth cattle, pigs, turkeys. It has potential for illegal use show racing animals because it may affect performance via its β-adrenergic agonist properties or anabolic activities. Nine greyhounds were orally administered 1 mg/kg of ractopamine investigate ability detect drug urine. Postdosing, 7 9 dogs developed cardiac arrhythmias had...
OBJECTIVE To investigate mechanisms by which anti-inflammatory doses of orally administered intermediate-acting glucocorticoids (prednisone) could predispose dogs to progression heart disease or congestive failure. ANIMALS 11 client-owned with allergic dermatitis and matched healthy control dogs. PROCEDURES Clinicopathologic, echocardiographic, hemodynamic variables were measured. Dogs then received prednisone (1 mg/kg, PO) once daily for 14 consecutive days beginning on day 0 (baseline),...
Mitral stenosis was diagnosed in 15 young to middle-aged dogs. There were 5 Newfoundlands and 4 bull terriers affected, suggesting a breed predisposition for this disorder. Clinical signs included cough, dyspnea, exercise intolerance, syncope. Soft left apical diastolic murmurs heard only dogs, whereas 8 dogs had systolic characteristic of mitral regurgitation. Left atrial enlargement the most prominent radiographic feature. Left-sided congestive heart failure detected by radiographs 11...
Background A 5‐year‐old, healthy English Springer Spaniel died suddenly 4 months after delivering a litter of 7 puppies. Within the dam's death, 3 offspring also suddenly. Hypothesis Abnormal cardiac repolarization, caused by an inherited long QT syndrome, is thought to be responsible for arrhythmias leading sudden death in this family. Animals Four remaining dogs from affected and 11 related dogs. Methods Physical examination resting ECG were done on littermates 9 Additional tests some or...
Baseline plasma norepinephrine (NE) and epinephrine (EPI) concentrations were measured in dogs with naturally acquired heart failure (HF) caused by either degenerative mitral valve disease regurgitation (MR) or idiopathic dilated cardiomyopathy (DCM). Compared controls (clinically normal), HF had increased NE concentration, which was correlated positively clinical severity of HF. Dogs the most severe degree (New York Heart Association functional class IV) mean concentration significantly (P...
Intracardiac rhabdomyosarcoma was diagnosed in a 14-month-old Golden Retriever referred for evaluation of syncope. The dog weak, with irregular heart rate, pulse deficit, murmur, and hepatomegaly. Thoracic radiography revealed generalized cardiomegaly, electrocardiography sinus rhythm multiform ventricular premature complexes intermittent tachycardia. Two-dimensional echocardiography extensive soft-tissue density masses both ventricles. An intracardiac neoplasm seen at postmortem examination...
Abstract Background Point‐of‐care lung ultrasound (LUS) is an effective tool to diagnose left‐sided congestive heart failure (L‐CHF) in dogs via detection of artifacts (B‐lines) caused by increased water. Hypothesis/Objectives To determine whether LUS can be used monitor resolution cardiogenic pulmonary edema dogs, and compare other indicators L‐CHF control. Animals Twenty‐five client‐owned hospitalized for treatment first‐onset L‐CHF. Methods Protocolized LUS, thoracic radiographs (TXR),...
The purpose of this study was to assess the effects systemic hypertension (SHT) on echocardiographic and radiographic cardiovascular variables in affected cats compared with healthy geriatric cats. Secondary objectives were determine whether there any relationships between these findings age or systolic blood pressure (SBP). Fifteen (<8 years normal SBP) 15 hypertensive (SBP > 180 mm Hg) studied. Each cat evaluated for standard parameters 4 different aortic root dimensions. Seventeen...
The purpose of this study was to assess the effects systemic hypertension (SHT) on echocardiographic and radiographic cardiovascular variables in affected cats compared with healthy geriatric cats. Secondary objectives were determine whether there any relationships between these findings age or systolic blood pressure (SBP). Fifteen (<8 years normal SBP) 15 hypertensive (SBP > 180 mm Hg) studied. Each cat evaluated for standard parameters 4 different aortic root dimensions. Seventeen...
Epidemiologic knowledge regarding noncardiovascular and all-cause mortality in apparently healthy cats (AH) with preclinical hypertrophic cardiomyopathy (pHCM) is limited, hindering development of evidence-based healthcare guidelines.
Twenty dogs with patent ductus arteriosus occluded Hemoclips were evaluated a mean follow-up time of 799.4 days (range, 83 to 3,580 days). Significant decreases found between pre- and postsurgical means for vertebral heart size echocardiographic left atrial/aortic-root ratios percent fractional shortening (%FS). Despite good clinical outcome, six 20 had persistent cardiomyopathy overload diminished %FS (28% or less) at follow-up. One dog residual ductal flow identified five postoperatively....
Twenty-four-hour ambulatory electrocardiograms were recorded in two age groups of 10 normal cats each: group 1 (1 to 4 years) and 2 (8 14 years), with equal numbers males females each group. Average heart rates over the 24-hour recording period ranged from 114 202 beats/minute (bpm). The mean average rate did not differ between (157.6 vs. 156.3+/-5.3 bpm, respectively); however, (both combined) had higher than (166.8 147.1+/-5.3 respectively). Females also a minimum (116.9 96.5+/-4.2 but...
Twenty‐four‐hour ambulatory electrocardiograms were recorded in two age groups of 10 normal cats each: group 1 (1 to 4 years) and 2 (8 14 years), with equal numbers males females each group. Average heart rates over the 24‐hour recording period ranged from 114 202 beats/minute (bpm). The mean average rate did not differ between (157.6 vs. 156.3 6 5.3 bpm, respectively); however, (both combined) had higher than (166.8 147.1 respectively). Females also a minimum (116.9 96.5 4.2 but there no...
Abstract OBJECTIVE To evaluate the clinicopathologic, hemodynamic, and echocardiographic effects of short-term administration anti-inflammatory dosages prednisolone to systemically normal cats. ANIMALS 10 cats with allergic dermatitis healthy control PROCEDURES Cats were randomly allocated 2 groups received (1 mg/kg/d, PO, for 7 days) in a crossover design followed by 9-day tapering 14-day washout periods. Each prednisolone-treated cat was matched on basis sex, neuter status, age (± 1 year),...
A 5-year-old, 29-kg, female Labrador retriever developed tachypnea, tachycardia, and ataxia following ingestion of approximately 48 mg/kg phenylpropanolamine. Initial diagnostic tests showed multiform ventricular left dilatation with a focal dyskinetic region in the dorsal interventricular septum, elevations creatinine kinase cardiac troponin I. All abnormalities resolved within 6 months. The transient electrocardiographic, echocardiographic, biochemical were consistent myocardial necrosis...