- Cardiovascular Conditions and Treatments
- Ultrasound in Clinical Applications
- Hemodynamic Monitoring and Therapy
- Pharmacological Effects and Assays
- Adipose Tissue and Metabolism
- Phonocardiography and Auscultation Techniques
- Veterinary Medicine and Surgery
- Cardiac Arrhythmias and Treatments
- Meat and Animal Product Quality
- Veterinary Oncology Research
- Mechanical Circulatory Support Devices
- Vascular anomalies and interventions
- Innovations in Medical Education
- Renin-Angiotensin System Studies
- Cardiovascular Disease and Adiposity
- Pulmonary Hypertension Research and Treatments
- Clinical Nutrition and Gastroenterology
- Diet and metabolism studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Hormonal and reproductive studies
- Congenital Heart Disease Studies
- Ultrasound Imaging and Elastography
- Thyroid Disorders and Treatments
- Gut microbiota and health
- Radiology practices and education
Iowa State University
2020-2025
Christensen Fund
2024
Purdue University West Lafayette
2021
Washington State University
2015-2017
Background The etiology of obesity‐related cardiac dysfunction ( ORCD ) is linked to metabolic syndrome in people. Studies have indicated that obese dogs components syndrome, warranting evaluation for dogs. Objectives To evaluate structure and function variables compared ideal weight Animals Forty‐six healthy, small‐breed (<25 pounds), (n = 29) 17). Methods A cross‐sectional study by standard strain echocardiographic measurements quantification serum (insulin:glucose ratios, lipid...
Abstract Background Systemic hypertension (SH) is a common cardiovascular disease in older cats that treated primarily with the calcium channel blocker amlodipine besylate (AML). The systemic effect of AML on classical and alterative arms renin‐angiotensin‐aldosterone system (RAAS) incompletely characterized. Hypothesis/Objectives To determine compared to placebo circulating RAAS biomarkers healthy using fingerprinting. Animals Twenty client‐owned cats. Methods Cats were administered (0.625...
Abstract Background Point‐of‐care lung ultrasound (LUS) is an effective tool to diagnose left‐sided congestive heart failure (L‐CHF) in dogs via detection of artifacts (B‐lines) caused by increased water. Hypothesis/Objectives To determine whether LUS can be used monitor resolution cardiogenic pulmonary edema dogs, and compare other indicators L‐CHF control. Animals Twenty‐five client‐owned hospitalized for treatment first‐onset L‐CHF. Methods Protocolized LUS, thoracic radiographs (TXR),...
Introduction Ultrasonographic indices of the inferior vena cava are useful for predicting right heart filling pressures in people. Objectives To determine whether ultrasonographic caudal (CVC) differ between dogs with right-sided CHF (R-CHF), left-sided (L-CHF), and noncardiac causes cavitary effusion (NC). Materials methods 113 diagnosed R-CHF (n = 51), L-CHF (30), or NC (32) were enrolled. Seventeen had pericardial tamponade. Focused ultrasound was performed prospectively to obtain...
Aortic body tumors, specifically chemodectomas, are the second most common type of canine cardiac tumor; however, information about treatment is currently lacking. This study included dogs with a presumptive or definitive diagnosis an aortic chemodectoma that underwent toceranib phosphate. Cases were solicited via American College Veterinary Internal Medicine Cardiology, Medicine, and Oncology listservs using electronic survey. Cox multivariate analysis factors potentially impacting survival...
Abstract Background Pimobendan is frequently used off‐label for treatments of cats with congestive heart failure (CHF). Concern exists regarding the safety pimobendan in outflow tract obstruction (OTO). Objectives In treated pimobendan, incidence adverse effects will not differ between OTO vs nonobstructive cardiomyopathy. Animals Two‐hundred sixty CHF (57 OTO, 203 disease). Methods Retrospective medical record review. Groups were compared using 2‐sample t ‐tests, Wilcoxon rank‐sum tests,...
Abstract Background The use of thyroid supplement is pervasive in athletic horses although its effects on measures performance are not known. Objectives One purpose this study was to determine whether supra‐physiologic doses levothyroxine affect the velocities at which blood lactate greater than 4 mmol/L (V La4 ) and heart rate over 150 200 beats per minute respectively. Additionally, a survey post‐race samples also conducted high thyroxine concentrations were common racehorses. Study design...
An 11 yr old castrated male greyhound presented to the Washington State University's Veterinary Teaching Hospital (WSU VTH) for evaluation of a 4 day history pleural effusion. The effusion had gelatinous appearance, suggestive mucus, and was characterized cytologically as pyogranulomatous exudate with some features carcinoma. Postmortem examination identified pulmonary mass evidence carcinomatosis. Pulmonary papillary adenocarcinoma carcinomatosis histologic diagnosis. Abundant mucin...
Diagnostic ultrasound is an important imaging modality in veterinary medicine. Surveys of veterinarians suggest that a desired clinical competence and new graduates are expected to practice basic skills. This report describes the development implementation training program core curriculum at Iowa State University College Veterinary Medicine (ISU-CVM). A multidisciplinary team ISU-CVM faculty created delivered consisting two lectures hands-on laboratories incorporated into second-year course,...
Clinical reasoning (CR) is an important clinical competency for effective veterinary practice. We hypothesized that implementing explicit 7-week CR curriculum taught in a large-enrollment elective cardiology course would improve students' awareness of principles, self-efficacy skills, and application principles case analyses. A secondary aim was to assess the impact peer review as means providing feedback large classroom setting. mixed method approach used with students ( N = 78) meeting...
Abstract Background Azotemia is common in cats with congestive heart failure (CHF) and might be exacerbated by diuretic therapy. Hypothesis/Objectives Determine frequency, risk factors, survival impact of progressive azotemia treated for CHF. Animals One hundred sixteen client‐owned kidney function testing performed at least twice during acute or chronic CHF treatment. Methods Serum creatinine (sCr) electrolyte concentrations were determined multiple clinical timepoints to detect injury (KI;...
To compare the use of curvilinear-array (microconvex) and phased-array transducers for ultrasonographic examination lungs in dogs.13 client-owned dogs with left-sided congestive heart failure.In a prospective methods comparison study, 24 examinations (4 sites/hemithorax) were performed both at 3 clinical time points. Two observers independently assessed number B lines (scored per site total), sites strongly positive (ie, those > lines/site), image quality on 5-point scale). Analyses included...
Abstract A 6‐year‐old neutered male 35 kg Staffordshire terrier dog was presented for evaluation of interdigital furunculosis. Culture from lesions revealed meticillin‐resistant Staphylococcus pseudintermedius , with susceptibility to only amikacin, chloramphenicol and vancomycin. Chloramphenicol administered at a dose 1500 mg orally every 8 hours (42 mg/kg) total 52 days. On Day treatment, new mid‐systolic click appreciated on cardiothoracic auscultation that prompted cardiac evaluation....