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Aude Frevol

ORCID: 0000-0002-8661-2942
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About
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A5066490999
Research Areas
  • Tuberculosis Research and Epidemiology
  • Immunodeficiency and Autoimmune Disorders
  • vaccines and immunoinformatics approaches
  • Infectious Diseases and Tuberculosis
  • Dermatology and Skin Diseases
  • Advancements in Transdermal Drug Delivery
  • Immunotherapy and Immune Responses
  • Leprosy Research and Treatment

Infectious Disease Research Institute
 2018-2023

Access to Wholistic and Productive Living Institute
 2023

 Safety and immunogenicity of the adjunct therapeutic vaccine ID93 + GLA-SE in adults who have completed treatment for tuberculosis: a randomised, double-blind, placebo-controlled, phase 2a trial
OPENALEX - Publications 
Tracey A. Day Adam Penn‐Nicholson Angelique Kany Kany Luabeya Andrew Fioré-Gartland Nelita du Plessis and 62 more André G. Loxton Julie Vergara Tom Rolf Tim Reid Asma Toefy Justin Shenje Hendrik Geldenhuys Michèle Tameris Simbarashe Mabwe Nicole Bilek Linda‐Gail Bekker Andreas H. Diacon Gerhard Walzl Jill A. Ashman Aude Frevol Zachary K. Sagawa Cecilia S. Lindestam Arlehamn Alessandro Sette Steven G. Reed Rhea N. Coler Thomas J. Scriba Mark Hatherill Anna Marie Beckmann Fan‐Chi Hsu Sarah Albertson Ashley Veldsman Constance Schreuder Erica Smit Yolundi Cloete Cynthia Ontong Elisabeth Filander Gail Jacobs Alana Keyser Hadn Africa Humphrey Mulenga Julia Noble Lebohang Makhethe Marcia Steyn Marwou de Kock Nambitha Quaqua Yiwen Lu Andrea Gutschmidt Friedrich Thienemann Stuart J. Kahn Angelique Mouton Elma van Rooyen Fajwa Opperman Ann Swarts Amaryl Van Schalkwyk Yolandi Herselman Devona Hofmeester Julia Amsterdam Leya Hassanally Linda van der Merwe Alessandro Companie Susan Rossouw Carolyn Jones Natasja Botes Elize van der Riet Sandra Goliath Sandra Krüger Eunice Sinandile

10.1016/s2213-2600(20)30319-2 article EN The Lancet Respiratory Medicine 2020-12-09
 Safety and immunogenicity of a thermostable ID93 + GLA-SE tuberculosis vaccine candidate in healthy adults
OPENALEX - Publications 
Zachary K. Sagawa Cristina Goman Aude Frevol Azra Blazevic Janice Tennant and 15 more Bridget S. Fisher Tracey A. Day Stephen P. Jackson Franck Lemiale Leon Toussaint Irene Kalisz Joe Wenjie Jiang Lisa Ondrejcek Raodoh Mohamath Julie Vergara Alan Lew Anna Marie Beckmann Corey Casper Daniel F. Hoft Christopher B. Fox

Abstract Adjuvant-containing subunit vaccines represent a promising approach for protection against tuberculosis (TB), but current candidates require refrigerated storage. Here we present results from randomized, double-blinded Phase 1 clinical trial (NCT03722472) evaluating the safety, tolerability, and immunogenicity of thermostable lyophilized single-vial presentation ID93 + GLA-SE vaccine candidate compared to non-thermostable two-vial in healthy adults. Participants were monitored...

10.1038/s41467-023-36789-2 article EN cc-by Nature Communications 2023-03-06
 The adjuvant GLA-AF enhances human intradermal vaccine responses
OPENALEX - Publications 
Darrick Carter Neal Van Hoeven Susan L. Baldwin Yotam Levin Efrat Kochba and 9 more Al Magill Nathalie Charland Nathalie Landry Khin Nu Aude Frevol Jill A. Ashman Zachary K. Sagawa Anna Marie Beckmann Steven G. Reed

We present an adjuvant for intradermal use that works in humans, enabling self-administration case of a flu pandemic.

10.1126/sciadv.aas9930 article EN cc-by-nc Science Advances 2018-09-07
 A phase 1 antigen dose escalation trial to evaluate safety, tolerability and immunogenicity of the leprosy vaccine candidate LepVax (LEP-F1 + GLA–SE) in healthy adults
OPENALEX - Publications 
Malcolm S. Duthie Aude Frevol Tracey A. Day Rhea N. Coler Julie Vergara and 5 more Tom Rolf Zachary K. Sagawa Anna Marie Beckmann Corey Casper Steven G. Reed

10.1016/j.vaccine.2019.12.050 article EN Vaccine 2019-12-30
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