Dongyan Zhang

ORCID: 0000-0002-8662-082X
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Research Areas
  • Probiotics and Fermented Foods
  • Gut microbiota and health
  • Animal Nutrition and Physiology
  • Clostridium difficile and Clostridium perfringens research
  • Bacteriophages and microbial interactions
  • Biopolymer Synthesis and Applications
  • Antimicrobial Peptides and Activities
  • Food Drying and Modeling
  • Microencapsulation and Drying Processes
  • Protein Hydrolysis and Bioactive Peptides
  • Occupational Health and Safety Research
  • Genomics and Phylogenetic Studies
  • Mycotoxins in Agriculture and Food
  • Agriculture Sustainability and Environmental Impact
  • Safety Warnings and Signage
  • Freezing and Crystallization Processes
  • Pediatric health and respiratory diseases
  • Oral microbiology and periodontitis research
  • Drug Transport and Resistance Mechanisms
  • Animal Behavior and Welfare Studies
  • Dermatology and Skin Diseases
  • Reproductive tract infections research
  • Meat and Animal Product Quality
  • Machine Learning in Bioinformatics
  • Reproductive System and Pregnancy

Liaocheng People's Hospital
2025

Lanzhou University
2025

Beijing Academy of Agricultural and Forestry Sciences
2013-2024

Henan Cancer Hospital
2024

Zhengzhou University
2024

Central South University of Forestry and Technology
2022-2023

Central South University
2022-2023

China University of Mining and Technology
2022

Northeast Agricultural University
2020

Harbin University
2020

Weaning disturbs the intestinal barrier function and increases risk of infection in piglets. Probiotics exert beneficial health effects, mainly by reinforcing epithelium modulating gut microbiota. However, mechanisms action, especially, specific regulatory effects modulated microbiota probiotics on have not yet been elucidated. The present study aimed to decipher protective probiotic Lactobacillus plantarum strain ZLP001 as well epithelial function. Paracellular permeability was measured...

10.3389/fmicb.2018.01953 article EN cc-by Frontiers in Microbiology 2018-08-24

Sows suffer oxidative stress and inflammation induced by metabolic burden during late pregnancy, which negatively regulates reproductive lactating performances. We previously found that L-malic acid (MA) alleviated improved performances in sows. However, the mechanism underlying MA’s positive effects remains unexplored. Here, twenty Large White × Landrace sows with similar parity were randomly divided into two groups fed a basal diet or supplemented 2% complex from day 85 of gestation to...

10.3390/antiox13020253 article EN cc-by Antioxidants 2024-02-19

Weaning stress renders piglets susceptible to pathogen infection, which leads post-weaning diarrhea, a severe condition characterized by heavy diarrhea and mortality in piglets. Enterotoxigenic Escherichia coli (ETEC) is one of typical strains associated with diarrhea. Thus, prevention inhibition ETEC infection are great concern. Probiotics possess anti-pathogenic activity can counteract infection; however, their underlying mechanisms modes action have not yet been clarified. In the present...

10.3389/fmicb.2018.01364 article EN cc-by Frontiers in Microbiology 2018-06-26

Three drying methods, including far infrared drying, convection and ultrasonic pretreatment assisted were adopted in the of ginger slices. The effects main parameters (ultrasonic power time, temperature power, sample thickness, temperature) on kinetics, energy consumption, color change investigated discussed detail. results showed that process slices was controlled by falling rate period. For increased with increase decrease while had no obvious effect process. fastest smallest change,...

10.1016/j.ultsonch.2022.106287 article EN cc-by-nc-nd Ultrasonics Sonochemistry 2022-12-30

DATA REPORT article Front. Physiol., 27 November 2018Sec. Gastrointestinal Sciences Volume 9 - 2018 | https://doi.org/10.3389/fphys.2018.01689

10.3389/fphys.2018.01689 article EN cc-by Frontiers in Physiology 2018-11-27

Host defense peptides (HDPs) have antimicrobial as well immunoregulatory activities and are involved in epithelial innate immune defense. Dietary modulation of endogenous HDP synthesis is an effective way to boost the host system. This study aimed investigate role probiotic Lactobacillus plantarum strain ZLP001 porcine induction underlying mechanism. To this end, we evaluated stimulatory effect L. on expression piglet intestinal tissue vivo IPEC-J2 cells 3D4/31 vitro, examined intracellular...

10.3389/fimmu.2019.02691 article EN cc-by Frontiers in Immunology 2019-11-19

Lactobacillus has a positive effect on the host intestinal microbiota. In piglets, dietary supplementation with affects general health and plays an important role in nutrient digestion fermentation. However, this association requires further investigation. Here, we studied newborn piglets from 12 litters. The nursed were given creep feed beginning day 10 post-partum weaned at 30. Piglets fed either control basic diet or including reuteri ZLR003 6.0 × 106 CFU/g feed. At 30 60, feces samples...

10.3389/fmicb.2019.00785 article EN cc-by Frontiers in Microbiology 2019-04-16

Lactobacillus johnsonii ZLJ010 is a probiotic strain isolated from the feces of healthy sow and has putative health-promoting properties. To determine molecular basis underlying potential genes involved in same, complete genome sequencing comparative analysis with L. were performed. The was found to contain single circular chromosome 1,999,879 bp guanine-cytosine (GC) content 34.91% encoded 18 ribosomal RNA (rRNA) 77 transfer (tRNA) genes. From among 1,959 protein coding sequences (CDSs),...

10.3389/fgene.2019.00812 article EN cc-by Frontiers in Genetics 2019-09-10

Background and Objectives: Diabetic Retinopathy (DR) has become the leading cause of vision impairment (VI) worldwide. Leveraging most recent data analytical techniques from Global Burden Diseases, Injuries, Risk Factors Study (GBD), we produced comprehensive estimates VI due to DR in Asia. These were segmented by location, age, gender for period between 1990 2021. Furthermore, projected burden up 2050. Methods: We analyzed GBD 2021 assess prevalence Years Lived with Disability (YLDs) Asia,...

10.52214/cujgh.v14i2.13122 article EN cc-by The Columbia University Journal of Global Health 2025-03-14

Abstract Pigeons, as the only altricial birds in poultry, are primary Trichomonas gallinae ( T. ) host. To study effects of infection on gut microbiota, we compared microbiota diversity and composition gastrointestinal (GI) tracts pigeons at age 14 21 day with different degrees infection. Thirty-six nestling were divided into three groups: healthy group, low-grade high-grade trichomonosis group. Then, crop, small intestine rectum contents obtained for sequencing 16S rRNA gene V3–V4...

10.1038/s41598-020-76821-9 article EN cc-by Scientific Reports 2020-11-17

In this study, we evaluated the effects of seven oligosaccharides on growth rate and stress tolerance Lactobacillus plantarum ZLP001 in vitro, potential synbiotic most effective oligosaccharide [fructo-oligosaccharide (FOS)] L. performance, apparent nutrient digestibility, fecal microbiota, serum immune index weaning piglets. Most were utilized as carbohydrate sources by ZLP001, but observed obvious differences bacterial depending type concentration. Oligosaccharides glucose significantly...

10.1093/jas/skz254 article EN Journal of Animal Science 2019-08-14

Abstract This study investigated the effects of Lactobacillus- fermented low-protein diet on growth performance, nitrogen balance, fecal microbiota, and metabolomic profiles finishing pigs. A total 90 pigs were assigned to one three dietary treatments including a normal protein (CON) as well two experimental diets in which supplemented with 0 (LP) or 1% Lactobacillus -fermented feed (FLP). In comparison CON, LP FLP significantly increased average daily gain ( P = 0.044), decreased ratio...

10.1038/s41598-024-58832-y article EN cc-by Scientific Reports 2024-04-14

Abstract The small intestine plays an essential role in the health and well-being of animals. Previous studies have shown that Lactobacillus has a protective effect on intestinal morphology, epithelium integrity appropriate maturation gut-associated tissues. Here, gene expression jejunum tissue weaned piglets was investigated by RNA-seq analysis after administration sterile saline, reuteri , or antibiotic (chlortetracycline). In total, 401 293 genes were significantly regulated...

10.1038/s41598-017-16158-y article EN cc-by Scientific Reports 2017-11-13

Objective This study was conducted to determine the effects of dietary supplementation with Pediococcus acidilactici (P. acidilactici) ZPA017 as a probiotic on reproductive performance, fecal microbial flora and serum indices in sows during late gestation lactation. Methods A total 94 (Large White×Yorkshire, average 4.50 parities) were randomly allotted two treatments: control diet supplemented P. (2.40×109 colony-forming unit/kg diets). The started at d 90 until 28 Results Compared fed...

10.5713/ajas.18.0764 article EN cc-by Asian-Australasian Journal of Animal Sciences 2019-05-27

Fetus loss in early pregnancy is of major concern to both humans and animals, this issue largely influenced by embryo implantation. Chenodeoxycholic acid (CDCA), a primary bile acid, contributes metabolic improvements protects against intrahepatic cholestasis pregnancy. However, the effect CDCA on implantation during has not been investigated. The present study demonstrated that administration improved sows rats, thereby improving outcomes sows. significantly reduced inflammation, oxidative...

10.3390/antiox13010008 article EN cc-by Antioxidants 2023-12-19

To conduct a comparative analysis of the efficacy, safety, and impact on quality life outcomes between thermal ablation surgical interventions in patients diagnosed with papillary thyroid carcinoma (PTC).

10.3389/fendo.2024.1398208 article EN cc-by Frontiers in Endocrinology 2024-08-01

Acetochlor has been widely used globally for its effective weed control, but the dietary intake of associated residues by people become a major concern nowadays. Milk is regarded as best solvent to dissolve pesticides due fat-rich characteristic. In this study, we aimed evaluate transfer acetochlor from feed raw milk. Twenty lactating Australian Holstein cows were randomly chosen and divided into 1 control group 3 treatment groups, feeding at dosages 0, 0.45, 1.35 4.05 g per day during...

10.1039/d0ra06895k article EN cc-by-nc RSC Advances 2020-01-01
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