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Jeffrey M. Snowbarger

ORCID: 0000-0002-8666-6975
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About
Contact & Profiles
A5065711569
Research Areas
  • Cancer Mechanisms and Therapy
  • Glioma Diagnosis and Treatment
  • Advanced biosensing and bioanalysis techniques
  • CRISPR and Genetic Engineering
  • Angiogenesis and VEGF in Cancer
  • Chromosomal and Genetic Variations

Discovery Institute
 2024

Sanford Burnham Prebys Medical Discovery Institute
 2024

Point Loma Nazarene University
 2021

 A novel method of screening combinations of angiostatics identifies bevacizumab and temsirolimus as synergistic inhibitors of glioma-induced angiogenesis
OPENALEX - Publications 
Michael I. Dorrell Heidi R. Kast-Woelbern Ryan T. Botts Stephen Bravo Jacob R. Tremblay and 25 more Sarah Giles Jessica F. Wada MaryAnn Alexander Eric Alejandro García Gabriel Villegas Caylor B. Booth Kaitlyn J. Purington Haylie M. Everett Erik N. Siles Michael Wheelock Jordan A. Silva Bridget M. Fortin Connor A. Lowey Allison L. Hale Troy L. Kurz Jack C. Rusing Dawn M. Goral Paul Thompson Alec M. Johnson Daniel J. Elson Roujih Tadros Charisa E. Gillette Carley Coopwood Amy L. Rausch Jeffrey M. Snowbarger

Tumor angiogenesis is critical for the growth and progression of cancer. As such, angiostasis a treatment modality cancer with potential utility multiple types fewer side effects. However, clinical success angiostatic monotherapies has been moderate, at best, causing treatments to lose their early luster. Previous studies demonstrated compensatory mechanisms that drive tumor vascularization despite use monotherapies, as well combination therapies overcome these mechanisms. We screened...

10.1371/journal.pone.0252233 article EN cc-by PLoS ONE 2021-06-02
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