- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatitis Pathology and Treatment
- Gallbladder and Bile Duct Disorders
- Colorectal Cancer Treatments and Studies
- Liver Disease and Transplantation
- Multiple and Secondary Primary Cancers
- Trauma and Emergency Care Studies
- Appendicitis Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Renal cell carcinoma treatment
- Trauma Management and Diagnosis
- Venous Thromboembolism Diagnosis and Management
- Organ Transplantation Techniques and Outcomes
- Enzyme Catalysis and Immobilization
- Enhanced Recovery After Surgery
- Cellular transport and secretion
- Intestinal Malrotation and Obstruction Disorders
- Sphingolipid Metabolism and Signaling
- Traumatic Brain Injury Research
- Gastrointestinal disorders and treatments
- Liver physiology and pathology
- Pediatric Hepatobiliary Diseases and Treatments
- Surgical Simulation and Training
Mayo Clinic
2020-2023
Carolinas Medical Center
2023
Carolinas Healthcare System
2023
Levine Cancer Institute
2023
WinnMed
2019-2022
Atrium Medical Cente
2021-2022
Mayo Clinic in Florida
2019-2021
Mayo Clinic in Arizona
2020
University of Calgary
2010-2018
The aim of this study was to evaluate the role surgical transgastric necrosectomy (TGN) for walled-off pancreatic necrosis (WON) in selected patients.WON is a common consequence severe pancreatitis and typically occurs 3 5 weeks after onset acute pancreatitis. When symptomatic, it can require intervention.A retrospective review patients with WON undergoing management at high-volume institutions performed. Surgical indications, intervention timing, technical methodology, patient outcomes were...
Background: Underutilization of operative management early stage pancreatic cancer is associated with sociodemographic variables, including age, race, facility type, insurance, and education. It currently unclear how these variables are survival in patients who undergo surgery. Methods: Patients clinical I adenocarcinoma were identified within the National Cancer Database (2010–2016). Utilization surgery nonoperative was determined. Nonclinical factors by multivariable analysis. The...
Platelet-stored serotonin critically affects liver regeneration in mice and humans. Selective reuptake inhibitors (SSRIs) noradrenalin (SNRIs) reduce intraplatelet serotonin. As SSRIs/SNRIs are now one of the most commonly prescribed drugs United States Europe given serotonin's impact on regeneration, we evaluated whether perioperative use outcome after hepatic resection.Consecutive patients undergoing resection (n = 754) were retrospectively included from prospectively maintained databases...
Structural and kinetic data show that Arg-599 of β-galactosidase plays an important role in anchoring the "open" conformations both Phe-601 active-site loop (residues 794-803). When alanine was substituted for Arg-599, shifted towards "closed" positions because interactions with guanidinium side chain were lost. Also, Phe-601, loop, Na+, which is ligated by backbone carbonyl lost structural order, as indicated large B-factors. IPTG, a substrate analog, restored R599A-β-galactosidase to open...
Abstract Background While emergent pancreatic resection for trauma has been previously described, no large contemporary investigations into the frequency, indications, and outcomes of pancreatectomy (EP) secondary to complications neoplastic disease exist. Modern perioperative data are currently unknown. Methods ACS-NSQIP was reviewed all non-traumatic resections (DP – distal pancreatectomy, PD - pancreaticoduodenectomy, or TP- total pancreatectomy) in patients with pancreatico-biliary...
# Outcomes and opportunities for improvement in self-inflicted blunt penetrating trauma {#article-title-2} Self-inflicted (SIT) is a public health issue ranking 4th as leading cause of death disability young adults. Retrospective descriptive analysis patients admitted to