A5001683266- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical studies and practices
- Safe Handling of Antineoplastic Drugs
- Patient Safety and Medication Errors
- Pharmaceutical Economics and Policy
- Pharmacy and Medical Practices
- Pharmacovigilance and Adverse Drug Reactions
- Electronic Health Records Systems
- Health, Medicine and Society
- Health Systems, Economic Evaluations, Quality of Life
- Medical Device Sterilization and Disinfection
- Healthcare Systems and Practices
- Antibiotics Pharmacokinetics and Efficacy
- Pharmacogenetics and Drug Metabolism
- Clinical Nutrition and Gastroenterology
- Medication Adherence and Compliance
- Simulation-Based Education in Healthcare
- Intravenous Infusion Technology and Safety
- Healthcare Technology and Patient Monitoring
- Quality and Safety in Healthcare
- Chemotherapy-related skin toxicity
- Disaster Response and Management
- Innovations in Medical Education
- Analytical Chemistry and Chromatography
- Neonatal Respiratory Health Research
University of Geneva
2016-2025
University Hospital of Geneva
2015-2024
Hôpital Beau-Séjour
2009-2024
Pharmac
2024
HES-SO Genève
2007-2024
HES-SO University of Applied Sciences and Arts Western Switzerland
2019-2023
Geneva College
1996-2022
University of Lausanne
2012-2022
University of Chicago
2010
Society for Healthcare Epidemiology of America
2010
To assess the feasibility and effectiveness of World Health Organization hand hygiene improvement strategy in a low-income African country.A before-and-after study from December 2006 through June 2008, with 6-month baseline evaluation period follow-up 8 months beginning intervention.University Hospital, Bamako, Mali. Participants. Two hundred twenty-four healthcare workers.The intervention consisted introducing locally produced, alcohol-based handrub; monitoring compliance; providing...
The aim of this study was to determine the temporal relation between use antibiotics and alcohol-based hand rubs (ABHRs) incidence methicillin-resistant Staphylococcus aureus (MRSA) Clostridium difficile.An interventional time-series analysis performed evaluate impact two promotion campaigns on consumption ABHRs assess their effect non-duplicate clinical isolates MRSA C. difficile from February 2000 through September 2006. This combined with a transfer function model aggregated data...
Abstract Background Adverse drug events contribute to rising health care costs. Clinical pharmacists can reduce their risks by identifying and solving drug-related problems (DRPs) through medication review. Aim To develop an economic model determine whether reviews performed clinical could lead a reduction in costs associated with the prevention of potential adverse events. Method Two during ward rounds internal medicine setting over one year. Avoided were estimated monetizing five...
Quantitative evaluation of safety after the implementation a computerized provider order entry (CPOE) system, stratification residual risks to drive future developments.Comparative risk analysis drug prescription process before and CPOE according Failure Modes, Effects Criticality Analysis (FMECA) method.The failure modes were defined their criticality indices calculated on basis likelihood occurrence, potential severity for patients, detection probability. handwritten electronic...
To determine the temporal relationship between antibiotic use and incidence of antibiotic-resistant Escherichia coli in both inpatient outpatient setting a large urban area.A retrospective observational time-series analysis was performed to evaluate non-duplicate clinical isolates E. resistant ciprofloxacin, trimethoprim/sulfamethoxazole cefepime from January 2000 through December 2007, combined with transfer function model aggregated data on settings obtained hospital's pharmacy billing...
Until recently, the preparation of paediatric parenteral nutrition formulations in our institution included re-transcription and manual compounding mixture. Although no significant clinical problems have occurred, re-engineering this high risk activity was undertaken to improve its safety. Several changes been implemented including new prescription software, direct recording on a server, automatic printing labels, creation file used pilot BAXA MM 12 compounder. The objectives study were...
To perform a risk analysis of the cancer chemotherapy process, by comparing five different organizations. quantitatively demonstrate usefulness centralization and information technologies, to identify residual risks that may be target additional actions.A reengineering process started in 1999 was planned finished 2006. The performed after at beginning technologies integration.Two thousand two hundred beds university hospital, with medical, surgical, haematological, gynaecological, geriatric,...
The direct influence of environmental cleanliness and risk manipulations on prepared syringes was evaluated.Media-fill testing used to estimate potential microbial contamination. Syringes were in three different environments using four uncontrolled high-risk manipulations. included an International Organization for Standardization (ISO) class 5 horizontal laminar-airflow hood ISO 6 cleanroom (in accordance with United States Pharmacopeia [USP] chapter 797), 7 drug preparation area operating...
The objective of this randomized, prospective and controlled study was to investigate the ability a closed-system transfer device (CSTD; BD-Phaseal) reduce occupational exposure two isolators 10 cytotoxic drugs compare standard compounding devices.The 6-month started with opening new unit. Two were set up 2 workstations each, one compound devices (needles spikes) other using Phaseal system. Drugs alternatively compounded in each isolator. Sampling involved wiping three surfaces (gloves,...
Background and Aim : Hospitalized patients requiring parenteral nutrition (PN) often need to receive intravenous (IV) medications as well. Y‐site administration is occasionally necessary, but physicochemical incompatibilities can occur between the PN. The aim of present study was assess physical compatibility 25 frequently coadministered IV a commercially available ready‐to‐use total Methods PN (NuTRIflex Lipid Special; B. Braun Medical AG, Sempach, Switzerland) were mixed in 1:1 (v/v)...
Background Drug manufacturers have developed “evergreening” strategies to compete with generic medication after patent termination. These include marketing of slightly modified follow-on drugs. We aimed estimate the financial impact these drugs on overall healthcare costs and also examine listing in hospital restrictive drug formularies (RDFs) system as a whole (“spillover effect”). Methods Findings used community pharmacy invoice office data Swiss canton Geneva calculate utilisation eight...
Introduction The external contamination and cross-contamination by cytotoxic drugs on the surface (outside septum) of 133 vials from various manufacturers available Swiss market were evaluated. All tested contained one following active ingredients: cyclophosphamide, cytarabine, doxorubicin, epirubicin, etoposide phosphate, gemcitabine, ifosfamide, irinotecan, methotrexate or vincristine. Methods materials validated wiping liquid chromatography-mass spectrometry method used in this study...
Potentially inappropriate medication (PIM) occurs frequently and is a well-known risk factor for adverse drug events, but its incidence underestimated in internal medicine. The objective of this study was to develop an electronic prescription-screening checklist assist residents young healthcare professionals PIM detection.Five-step involving selection medical domains, literature review 17 semistructured interviews, two-round Delphi survey, forward/back-translation process tool...