A5069202690- Renal Diseases and Glomerulopathies
- Urticaria and Related Conditions
- Economic and Business Development Strategies
- Economic and Technological Systems Analysis
- Economic and Technological Developments in Russia
- Vasculitis and related conditions
- Global Healthcare and Medical Tourism
- Medical and Biological Sciences
- Systemic Lupus Erythematosus Research
- T-cell and B-cell Immunology
- Healthcare Systems and Public Health
- Health and Conflict Studies
- Global Health Care Issues
- Systemic Sclerosis and Related Diseases
- Erythrocyte Function and Pathophysiology
- Mast cells and histamine
- Reproductive System and Pregnancy
- Atherosclerosis and Cardiovascular Diseases
Institute of Nephrology of the National Academy of Medical Sciences of Ukraine
2016-2022
Abstract. The Institute of Nephrology the Academy Medical Sciences Ukraine was established in 2001. Since then, has been constantly evolving and, currently, it is a national scientific, methodological and medical center field nephrology. achievements Institute's staff are recognized world scientific community. article presents an analysis results activities for 2001-2021.
Introduction. Cytokines and HLA are of important part immunogenesis many diseases, therefore the analysis these indices this associations in dependence glomerulonephritis (GN) can define their value as additional prognostic markers.
 Aim work is to determine peculiarities high serum levels ofproinflammatory cytokines (TNF a, MCP-1, IL-18) some phenotype substantiate chronic with nephrotic syndrome (CGN, NS) ascertain Materials methods. There was studied HLA-antigens distribution 264...
Abstract. The occurrence of an emergency situation (ES) forced international (ISN, EDTA/ERA) and national (Turkey) nephrological associations to establish the Renal Disaster Relief Task Force, which is primarily concerned with treatment patients acute kidney injury end-stage renal disease requiring dialysis. war started by RF putting Ukrainian state, society, healthcare system in catastrophic ES. Under these circumstances, all became one most vulnerable categories patients.
 To provide...
The purpose of study was determination HLA -antigens I and II classes as predictors ineffectiveness initial steroid therapy, according prognozonegative markers chronic glomerulonephritis with nephrotic syndrome.
 Methods. In 59 syndrome patients (steroid sensitive n=33 (1 gr.) resistant’s n= 26 (2 gr.)) 350 healthy donors( control group) studied antigens the special anti- HLA-antigens panel (20 locus A, 31 – B 9- DR).
 Result. glomerulonephritis, hormone sensitivity relative risk...
In the work was determined HLA-phenotype specificities in patients with different morphologic forms of chronic glomerulonephritis and nephrotic syndrome (CGN, NS) to define additional predictors a disease course.
 Materials methods. There studied HLA-antigens distribution 264 CGN, NS 350 healthy donors by typing lymphocytes aid ofstandard microlymphocytotoxic test (Terasaki’s test). The diagnosis confirmed morphologically using thin needle nephrobiopsy.
 Results. It is advisable...
It was to determine associations the serum levels ofVEGF and with HLA inpatients chronic glomerulonephritis nephrotic syndrome (CGN, NS).
 Materials methods. There studied of VEGF (80 patients) by ELIZA HLA-antigens distribution in CGN, NS patients (534) typing lymphocytes aid standard microlymphocytotoxic test (Terasaki’s test). The diagnosis confirmed morphologically using nephrobiopsy.
 Results. HLA-A, В antigens 2 group having various is shown. Associations some high vascular...
Cytokines and HLA take important part in immunogenesis of many diseases, therefore the analysis these indices this associations dependence glomerulonephritis (GN) can define their value as additional prognostic markers.
 Aim work is to determine high serum levels cytokines (IL-4, IL-17) peculiarities some phenotype substantiate chronic with nephrotic syndrome (CGN, NS) immunogen- esis ascertain Materials methods. There was studied HLA-antigens distribution 264 adult patients CGN, NS...
Мета роботи: визначити особливості HLA-фенотипів та показників цитокінової ланки імунітету з факторами ендотеліальної дисфункції у хворих на непроліферативні (НП) форми хронічного гломерулонефриту (ХГН) нефротичним синдромом (НС).
 Матеріал методи. Вивчали розподіл HLA-антигенів за допомогою мікролімфоцитотоксичного тесту Терасакі 264 ХГН, НС (серед яких аналізували дані 96 НП ГН) 350 здорових донорів. Морфологічний діагноз був підтверджений методом тонкоігольної нефробіопсії. Для...
Studies devoted to the role of human leucocyte antigens (HLA) in pathogenesis chronic kidney disease (CKD) have demonstrated associative links HLA antigens, which stipulate relative and attributive risks some autoimmune diseases, with immune disorder a high production pro-inflammatory cytokines.
 The aim our study was determine peculiarities phenotypes CKD patients according distribution HLA-A, B DR conduct their comparative analysis pyelonephritis (PN) glomerulonephritis (GN).
...
In December 2021, the State Institution "Institute of Nephrology National Academy Medical Sciences Ukraine celebrates its 20th anniversary. It is a modern research, medical-diagnostic and organizational-methodical institution that ensures implementation state policy in Nephrology. Scientific topics performed by staff institute are aimed at improving diagnostic methods treatment patients with glomerulonephritis, pyelonephritis, inhibiting progression chronic kidney disease, quality life...