A5050877879- Advanced Sensor and Energy Harvesting Materials
- Hydrogels: synthesis, properties, applications
- Advanced Materials and Mechanics
- Conducting polymers and applications
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Polymer Surface Interaction Studies
- Orthopedic Infections and Treatments
- 3D Printing in Biomedical Research
- Bone Tissue Engineering Materials
- Advanced Polymer Synthesis and Characterization
- biodegradable polymer synthesis and properties
- Electrospun Nanofibers in Biomedical Applications
- Advanced materials and composites
- Nanoparticle-Based Drug Delivery
- Tactile and Sensory Interactions
- Nanoplatforms for cancer theranostics
- Graphene and Nanomaterials Applications
- Dielectric materials and actuators
- Analytical Chemistry and Sensors
- Osteoarthritis Treatment and Mechanisms
- Polydiacetylene-based materials and applications
- Block Copolymer Self-Assembly
- Periodontal Regeneration and Treatments
- Surgical Sutures and Adhesives
Sun Yat-sen University
1999-2025
Xuzhou Central Hospital
2025
Chinese People's Liberation Army
2018-2024
Chinese PLA General Hospital
2021-2024
Mengchao Hepatobiliary Hospital
2024
Fujian Medical University
2024
Sartorius (United States)
2014-2024
Shandong Institute of Automation
2024
Peking University
2011-2023
Tsinghua University
2020-2023
Abstract Articular cartilage has poor ability to heal once damaged. Tissue engineering with scaffolds of polymer hydrogels is promising for regeneration and repair. Polymer composed highly hydrated crosslinked networks mimic the collagen extracellular matrix thus are employed as inserts at defects not only temporarily relieve pain but also support chondrocyte proliferation neocartilage regeneration. The biocompatibility, biofunctionality, mechanical properties, degradation most important...
It is desired to create skin strain sensors composed of multifunctional conductive hydrogels with excellent toughness and adhesion properties sustain cyclic loadings during use facilitate the electrical signal transmission. Herein, we prepared transparent, compliant, adhesive zwitterionic nanocomposite mechanical properties. The incorporated polymers can form interchain dipole-dipole associations offer additional physical cross-linking network. show a high fracture elongation up 2000%,...
Biocompatible conductive hydrogels with intrinsic flexibility, high sensitivity, linearity and outstanding reliability are highly demanded for wearable devices or implantable sensors. Here we report novel tough composed of interpenetrating polyaniline (PANI) poly(acrylamide-co-hydroxyethyl methyl acrylate) (P(AAm-co-HEMA)) networks. Intrinsic interactions between the PANI network flexible P(AAm-co-HEMA) endowed strength toughness to cyclic loadings. The show very sensitivity (gauge factor...
Stretchable, self-healing, and fatigue resistant polyzwitterionic nanocomposite hydrogels with polydopamine robustly adhere to the heart lungs for <italic>in situ</italic> monitoring of dynamic motions through wireless transmission.
Nanocomposite hydrogels with unprecedented stretchability, toughness, and self-healing have been developed by in situ polymerization of acrylamide the presence exfoliated montmorillonite (MMT) layers as noncovalent cross-linkers. The MMT clay nanoplatelets high aspect ratios, confirmed transmission electron microscopy (TEM) X-ray diffraction (XRD) results, are well dispersed polyacrylamide matrix. Strong polymer/MMT interaction was Fourier transform infrared spectroscopy (FTIR) differential...
We have successfully developed hydrogels with high compressive toughness by reinforcing the double-network structure (PAMPS/PAAm) grafted silica nanoparticles. Silica nanoparticles vinyl end groups were used as macro-crosslinkers to copolymerize AMPS, yielding a nanocomposite first network. Subsequent introduction of secondary PAAm network resulted in super-tough (DN) composite hydrogels, which do not fracture upon loading up 73 MPa and strain above 0.98. The strength, swelling behavior,...
Tough and self-adhesive zwitterionic hydrogels with ionic conductivity have been prepared, showing high linear strain sensitivity for detecting human motions.
Vinyl-functionalized thermosensitive Pluronic F127 micelles have been used as multifunctional cross-links for the synthesis of super tough, highly resilient and thermoresponsive nanomicelle (NM) hydrogels. diacrylate (F127DA) with vinyl groups on both ends self-assembled in aqueous solution into micelles. Such served macro-cross-links to copolymerize acrylamide (AAm) monomers, generating novel NM hydrogels extraordinary tensile compressive properties, without using any chemical...
Abstract Biocompatible hydrogel inks with shear‐thinning, appropriate yield strength, and fast self‐healing are desired for 3D bioprinting. However, the lack of ideal bioprinting outstanding printability high structural fidelity, as well cell‐compatibility, has hindered progress extrusion‐based tissue engineering. In this study, novel self‐healable pre‐cross‐linked microparticles ( pc HμPs) chitosan methacrylate (CHMA) polyvinyl alcohol (PVA) hybrid hydrogels developed used bioinks printing...
Biomimetic constructs imitating the functions, structures, and compositions of normal tissues are great importance for tissue repair regeneration. Three-dimensional (3D) printing is an innovative method to construct intricate biomimetic 3D engineering scaffolds with spatiotemporal deposition materials control intrinsic architectural organization functional performance scaffold. However, due lack bioinks suitable printability, high structural integrity, biological compatibility, producing...
Abstract Adhesive hydrogels have broad applications in tissue adhesives, hemostatic agents, and biomedical sensors. Various bio‐inspired glues synthetic adhesives are clinically used as conventional agents auxiliary tools for wound closure. Medical needed to effectively quickly control bleeding, thereby reducing the risk of complications caused by severe blood loss. sensors need excellent skin compliance, mechanical properties, sensitivity, biological safety. This review focuses on recent...
Human-machine interaction (HMI) technology shows an important application prospect in rehabilitation medicine, but it is greatly limited by the unsatisfactory recognition accuracy and wearing comfort. Here, this work develops a fully flexible, conformable, functionalized multimodal HMI interface consisting of hydrogel-based sensors self-designed flexible printed circuit board. Thanks to component regulation structural design hydrogel, both electromyogram (EMG) forcemyography (FMG) signals...
Thermochromic smart windows are widely developed to modulate building energy exchange save consumption. However, most have fixed working temperatures, moderate energy-saving efficiency, and not suitable for diverse (cold hot) climates. Here with strong temperature modulation over a broad range of hydrogels adjustable transition temperatures all-weather regulation in different climates reported. poly(N-isopropylacrylamide-co-N, N-dimethylacrylamide) hydrogels, lower critical ranging from 32.5...
Information encryption technologies are very important for security, health, commodity, and communications, etc. Novel information mechanisms materials desired to achieve multimode reprogrammable encryption. Here, a supramolecular strategy is demonstrated multimodal, erasable, reprogrammable, reusable by reversibly modulating fluorescence. A butyl-naphthalimide with flexible ethylenediamine functionalized β-cyclodextrin (N-CD) utilized as fluorescent responsive ink printing or patterning on...
Hydrogel-based wearable flexible pressure sensors have great promise in human health and motion monitoring. However, it remains a challenge to significantly improve the toughness, sensitivity stability of hydrogel sensors. Here, we demonstrate fabrication hierarchically structured by 3D printing microgel-reinforced double network (MRDN) hydrogels achieve both very high mechanical toughness. Polyelectrolyte microgels are used as building blocks, which interpenetrated with second network,...
Ion conductive hydrogels (ICHs) have attracted great interest in the application of ionic skin because their superior characteristics. However, it remains a challenge for ICHs to achieve balanced properties high strength, large fracture strain, self-healing and freezing tolerance. In this study, strong, stretchable, antifreezing ICH was demonstrated by rationally designing multiphysically cross-linked network structure consisting hydrophobic association, metal-ion coordination chain...
Conductive hydrogels have garnered significant attention in the realm of flexible electronic strain transducers (FESTs). However, development such FEST has been hindered by weak mechanical performance and low conductivity, sensitivity, stability. In this study, we introduce a novel hydrogel with wrinkled surface possessing unique ability to differentiate between different spoken written languages. Our approach involved fabricating robust, tough, ionic conductive texture through simple...
Smart windows based on thermoresponsive materials can modulate solar radiation to save building energy. Next generation smart that not only transmission, but also convert and store energy through new power technologies.
Metal-organic frameworks (MOFs) have numerous applications, such as energy storage, medical delivery, and wastewater remediation. Nevertheless, their applications to conductive hydrogels are restricted due limited dispersion, aggregation...
Acute wounds subject to frequent deformations are difficult be treated because the healing process was easily interfered by external mechanical forces. Traditional wound dressings have limited efficacy of their poor properties and skin adhesiveness difficulty in delivery therapeutic drugs effectively. As such, tough skin-adhesive with sustainable stimuli-responsive drug release for treatment those highly desirable. For this purpose, we developed a mechano-responsive poly(sulfobetaine...