Yunchao Xiao

ORCID: 0000-0002-8737-8027
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About
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Research Areas
  • Electrospun Nanofibers in Biomedical Applications
  • Advanced Sensor and Energy Harvesting Materials
  • Graphene and Nanomaterials Applications
  • 3D Printing in Biomedical Research
  • Conducting polymers and applications
  • biodegradable polymer synthesis and properties
  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques
  • Advanced Materials and Mechanics
  • Nanoparticle-Based Drug Delivery
  • Bone Tissue Engineering Materials
  • Cancer Cells and Metastasis
  • Electrohydrodynamics and Fluid Dynamics
  • Flame retardant materials and properties
  • Metal and Thin Film Mechanics
  • Additive Manufacturing and 3D Printing Technologies
  • Carbon dioxide utilization in catalysis
  • Dendrimers and Hyperbranched Polymers
  • Nanoplatforms for cancer theranostics
  • Microfluidic and Bio-sensing Technologies
  • Extracellular vesicles in disease
  • Silk-based biomaterials and applications
  • Advanced Drug Delivery Systems
  • Nanopore and Nanochannel Transport Studies
  • Characterization and Applications of Magnetic Nanoparticles

Jiaxing University
2021-2024

Donghua University
2018-2021

State Key Laboratory for Modification of Chemical Fibers and Polymer Materials
2018-2021

Jiangnan University
2018

Taiyuan University of Technology
2016-2017

Stimuli-responsive hydrogels are a class of important materials for the preparation flexible sensors, but development UV/stress dual-responsive ion-conductive with excellent tunability wearable devices remains major challenge. In this study, multifunctional hydrogel (PVA-GEL-GL-Mo7) high tensile strength, good stretchability, outstanding flexibility, and stability is successfully fabricated. The prepared has an strength 2.2 MPa, tenacity 5.26 MJ/m3, favorable extensibility (522%),...

10.1021/acsami.3c03920 article EN ACS Applied Materials & Interfaces 2023-05-15

Development of versatile and powerful nanoplatforms for efficient therapeutic delivery represents a major topic current nanomedicine. Herein, we present the development core-shell tecto dendrimers (CSTDs) co-delivery gene drug enhanced anticancer therapy applications. In this work, CSTDs were first prepared via supramolecular recognition β-cyclodextrin (CD)-decorated generation 5 (G5) poly(amidoamine) (PAMAM) as cores adamantane (Ad)-functionalized G3 PAMAM shell components. The formed with...

10.1039/d0tb00346h article EN Journal of Materials Chemistry B 2020-01-01

Detection of circulating tumor cells (CTCs) in peripheral blood is paramount significance for early-stage cancer diagnosis, estimation development, and individualized therapy. Herein, we report the development hyaluronic acid (HA)-functionalized electrospun chitosan nanofiber (CNF)-integrated microfludic platform highly specific capture nondestructive release CTCs. First, CNFs were formed modified with zwitterion carboxyl betaine acrylamide (CBAA) via Michael addition reaction then targeting...

10.1021/acs.bioconjchem.7b00747 article EN Bioconjugate Chemistry 2018-02-07

The review reports recent advances in the design of functional electrospun nanofibers for cancer cell capture applications.

10.1039/c7tb03347h article EN Journal of Materials Chemistry B 2018-01-01

The isolation of viable circulating tumor cells (CTCs) from blood is paramount significance for early stage detection and individualized therapy cancer. Currently, CTCs isolated by conventional magnetic separation methods are tightly coated with materials even after attempted coating removal treatments, which not conducive subsequent analysis CTCs. Herein, we developed DNA aptamer-functionalized short nanofibers (aptamer-MSNFs) efficient capture release In our work, polyethylenimine...

10.1021/acs.bioconjchem.9b00816 article EN Bioconjugate Chemistry 2019-12-19

Zwitterion-functionalized aligned nanofibers integrated with a microfluidic chip can be used for highly efficient capture and rapid release of CTCs.

10.1039/c7qm00570a article EN Materials Chemistry Frontiers 2018-01-01

REMA is a more reliable and accurate approach for cytocompatibility evaluation of nanofibrous materials than MTT assay.

10.1039/c8ay02310g article EN Analytical Methods 2018-12-11

LDH-incorporated PLGA short nanofibers can be loaded with dual drugs for multistage release and chemotherapy of drug-resistant cancer cells.

10.1039/d1nj02159a article EN New Journal of Chemistry 2021-01-01

To develop a multifunctional nanofibrous mat-embedded microfluidic chip system for specific capture and intact release of circulating tumor cells.Electrospun polyethylenimine/polyvinyl alcohol nanofibers were functionalized with zwitterions to reduce the nonspecific adhesion blood cells, followed by modification arginine-glycine-aspartic acid peptide via an acid-sensitive benzoic imine bond.The nanofiber-embedded microchip can be applied capturing various types cancer cells high efficiency...

10.2217/nnm-2018-0150 article EN Nanomedicine 2018-12-19

In this study, two-dimensional Ti3C2 nanosheets were employed to improve the tribological and thermo-mechanical properties of epoxy resin. The prepared by ultrasound-assisted delamination multilayered microparticles, nanosheets/epoxy (Ti3C2/epoxy) nanocomposites fabricated through physical blending curing reaction. Scanning electron microscopy results showed that dispersed uniformly in matrix. Tribological test wear rate Ti3C2/epoxy was only 6.61 × 10-14 m3/(N m) at a 1% mass fraction, which...

10.1021/acsomega.1c04620 article EN cc-by-nc-nd ACS Omega 2021-10-22

To simultaneously improve the flame retardancy, strength and toughness of polylactic acid (PLA) fibers, a composite retardant CNTs-H-C was prepared with carbon nanotubes (CNTs) as core, hexachlorocyclotriphosphazene linker, chitosan grafted on surface. The introduced into PLA matrix to obtain CNTs-H-C/PLA composites fibers via melt-blending method. morphology, structure, properties mechanical were thoroughly characterized, mechanism studied. Results showed that displayed nanotube-like...

10.1039/d2ra04130h article EN cc-by-nc RSC Advances 2022-01-01

Abstract Inherent brittleness and poor wear resistance of epoxy resin severely restricts its practical application in many applications. In this present, a micro‐nano structured ZrO 2 /Ti 3 C particle was employed to improve the tribological thermo‐mechanical properties resin. The particles are synthesized by hydrothermal growth nano‐ZrO onto surface accordion‐like Ti , /epoxy composites fabricated solution blending curing reaction. morphology fracture were investigated. Test results...

10.1002/app.51209 article EN Journal of Applied Polymer Science 2021-05-29

Wide temperature tolerance and superior mechanical properties are highly required for composite hydrogels in electronic applications such as skins soft robotics. In this work, a unique polyacrylamide-based double-network hydrogel system is designed fabricated by introducing graphene oxide glycerol to improve well antifreezing antiheating properties. Maximum stress of the oxide-incorporated increases rapidly 500.0 kPa which much higher than that polymetric acrylamide/carboxymethylcellulose...

10.1021/acsomega.3c05779 article EN cc-by-nc-nd ACS Omega 2023-11-27

Skin-like body sensors have important applications in soft-bodied intelligent robots, electronic skins, and medical health monitoring.

10.1039/d3tc03359g article EN Journal of Materials Chemistry C 2023-12-05
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