Sofia Alegria

ORCID: 0000-0002-8745-3541
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Pulmonary Hypertension Research and Treatments
  • Venous Thromboembolism Diagnosis and Management
  • Acute Myocardial Infarction Research
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Valve Diseases and Treatments
  • Cardiac Imaging and Diagnostics
  • Congenital Heart Disease Studies
  • Coronary Interventions and Diagnostics
  • Acute Ischemic Stroke Management
  • Vascular Anomalies and Treatments
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Structural Anomalies and Repair
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiovascular Issues in Pregnancy
  • Cardiovascular Function and Risk Factors
  • Streptococcal Infections and Treatments
  • Cardiovascular Effects of Exercise
  • Cardiac pacing and defibrillation studies
  • Cardiomyopathy and Myosin Studies
  • Heart Failure Treatment and Management
  • Aortic Disease and Treatment Approaches
  • Antimicrobial Resistance in Staphylococcus
  • Cardiac tumors and thrombi
  • Cardiovascular and Diving-Related Complications

Hospital Garcia de Orta
2017-2024

Hospital de São João
2017

Hospital de Santo António
2017

Hospital de Santa Marta
2017

The Strategic Plan for Cardiovascular Health in Portugal is an initiative of the Portuguese Society Cardiology, developed together with European Cardiology to create a Plan, which has now been endorsed by Council Union. Building upon its conceptual framework, moved executing phase establishing Working Groups composed experts priority areas. Guided strategic pillars, these groups formulated action proposals encompassing health promotion, primary prevention and determinants, screening early...

10.1016/j.repc.2025.03.003 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2025-03-01

Fundamento: A endocardite infecciosa (EI) está associada a complicações graves e alta mortalidade. avaliação das taxas de mortalidade preditores eventos fatais é importante para identificar fatores modificáveis relacionados ao padrão tratamento, com o objetivo melhorar os desfechos. Objetivos: Avaliar desfechos clínicos pacientes EI determinar hospitalar. Métodos: Estudo retrospectivo centro único, incluindo admitidos durante um período 10 anos (2006-2015). Foram avaliados dados...

10.36660/abc.20180194 article PT cc-by-nc Arquivos Brasileiros de Cardiologia 2019-01-01

BACKGROUND:Stress echocardiography has a 72%-85% sensitivity and an 80%-95% specificity.In this study, we characterized patients who received false-positive stress echocardiogram result.METHODS: A total of 5,256 underwent (induced by exercise, dobutamine, or dipyridamole) between 2009 to 2018, 405 (7.7%) positive result.Among the patients, 300 coronary angiography within 12 months, these were included in study (mean age = 64.9± 9.4 years, 230 men [76.7%]).Coronary artery disease was...

10.4250/jcvi.2019.0109 article EN cc-by-nc Journal of Cardiovascular Imaging 2020-01-01

Reperfusion therapy is generally recommended in acute high-risk pulmonary embolism (HR-PE), but several population-based studies report that it underused. Data on epidemiology, management and outcomes of HR-PE Portugal are scarce.

10.1016/j.repc.2023.07.005 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2023-11-06

This study describes the experience of a reference center using continuous aspiration mechanical thrombectomy for acute high- and intermediate-high-risk pulmonary embolism (PE).Twenty-nine consecutive patients with central PE (48.3% high-risk PE; 82.8% in class >III from original Pulmonary Embolism Severity Index score; median Charlson Comorbidity 4) were treated Indigo® Mechanical Thrombectomy System between March 2018 2020. Technical success was defined as successful placement device...

10.1016/j.repc.2021.04.009 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2022-05-27

Summary Pheochromocytoma/paraganglioma (PPGL) are neuroendocrine tumors that can secrete catecholamines. The authors describe a challenging case who presented as stress cardiomyopathy and myocardial infarction (MI). A 76-year-old man, with medical history of Parkinson’s disease, type 2 diabetes mellitus, hypertension, dyslipidaemia previous inferior MI in 2001, to the emergency department due chest pain, headaches vomiting. He also reported worsening blood glucose levels increasing...

10.1530/edm-19-0017 article EN cc-by-nc-nd Endocrinology Diabetes and Metabolism Case Reports 2019-04-16

Balloon pulmonary angioplasty (BPA) has emerged as a promising therapeutic option for patients with chronic thromboembolic hypertension (CTEPH) who are not eligible thromboendarterectomy (PEA) or have recurrent persistent after surgery. There is no standardized technique BPA and, its complexity and high risk of severe complications, requires skills appropriate training should be reserved expert CTEPH centers, complementary intervention to medical surgical therapy. The purpose this document...

10.1016/j.repc.2020.11.014 article PT cc-by-nc-nd Revista Portuguesa de Cardiologia 2021-08-06

Glossopharyngeal neuralgia is a rare facial pain syndrome, which in more cases can be associated with syncope. We present the outcome of case report that combines this association received medical therapy anti-epileptic medication and permanent dual chamber pacemaker implantation. In case, syncope episodes were both vasodepressor cardioinhibitory reflex types. The patient found relief from syncope, hypotension, after initiation therapy. Although was implanted, interrogation revealed no...

10.1016/j.repc.2019.12.013 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2023-04-03

Introduction and Objectives:The true prevalence of chronic thromboembolic pulmonary hypertension (CTEPH) after embolism (PE) in the Portuguese population remains unknown.We aimed to assess predictors CTEPH two years a symptomatic high-(HR) or intermediate-high risk (IHR) PE.Methods: We conducted retrospective cohort study patients admitted with PE between 2014 2019 referral center for hypertension.Results: In this single-center registry 969 (annual incidence 46/100 000 population), 194 had...

10.1016/j.repc.2023.06.007 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2023-08-30

Background: Neurological complications are common in patients with infective endocarditis (IE). Recent data suggest that neurologic events a major determinant of prognosis, and surgery is critical improving the outcome. Objective: To characterize IE neurological to determine predictors embolization central nervous system (CNS) mortality. Methods: Retrospective analysis admitted tertiary center diagnosis from 2006 2016. Statistical significance was defined by [...]

10.36660/abc.20190586 article EN cc-by-nc Arquivos Brasileiros de Cardiologia 2021-04-01

Balloon pulmonary angioplasty (BPA) is an alternative therapy in patients with inoperable chronic thromboembolic hypertension (CTEPH) or residual/recurrent (PH) after surgery. The aim of this study was to assess the short-term efficacy and safety a BPA program.This prospective single-center included all sessions performed CTEPH between 2017 2019. Clinical assessment including WHO functional class, plasma biomarkers, 6-min walk test (6MWT) right heart catheterization at baseline six months...

10.1016/j.repce.2021.05.001 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia (English Edition) 2021-10-01

Introduction:The standard of care for acute ST-elevation myocardial infarction (STEMI) includes the activation a STEMI network, administration adjuvant medical therapy, and reperfusion through primary percutaneous coronary intervention (PCI).While PCI is nowadays first option treatment patients with STEMI, antithrombotic including antiplatelet anticoagulant agents, cornerstone pharmacological to optimize their clinical outcomes.Objective: The aim this study was describe contemporaneous...

10.1016/j.repc.2019.02.015 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2019-11-01

Balloon pulmonary angioplasty (BPA) is an alternative therapy in patients with inoperable chronic thromboembolic hypertension (CTEPH) or residual/recurrent (PH) after surgery. The aim of this study was to assess the short-term efficacy and safety a BPA program.

10.1016/j.repc.2020.10.016 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2021-06-26

Pulmonary hypertension (PH) is one of the most feared complications systemic sclerosis (SSc). There are currently specific drugs approved for PH group I (pulmonary arterial - PAH), but related to lung disease (group III) use vasodilators still controversial and not routinely recommended in patients with non-severe PH. However, SSc-PH-interstitial (ILD) has a poorer survival compared SSc-PAH, making management these challenge, ideally carried out reference centre. Herein we report case...

10.63032/bbmb6759 article EN ARP Rheumatology 2024-06-30

The Strategic Plan for Cardiovascular Health in Portugal is an initiative of the Portuguese Society Cardiology, aligned with efforts by European Cardiology and World Heart Federation to develop national plans, at a local level within cultural socio-economic contexts, focused on cardiovascular health. overarching goal promote ensure continuous sustained improvement health population.The methodology identified key challenges opportunities medium term, highlighted priority areas intervention,...

10.1016/j.repc.2024.11.006 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2024-11-01

In acute coronary syndromes (ACS), the optimal revascularization strategy for unprotected left main artery (ULMCA) culprit lesion has been under-investigated. Therefore, we compared clinical characteristics and short- medium-term outcomes of percutaneous surgical in ACS.Of 31886 patients enrolled a multicenter, national, prospective registry study between October 2010 December 2020, 246 (0.8%) had ULMCA as underwent intervention (PCI) alone (n=133, 54%) or bypass grafting (CABG) (n=113,...

10.1016/j.repc.2022.07.019 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2023-03-21

The standard of care for acute ST-elevation myocardial infarction (STEMI) includes the activation a STEMI network, administration adjuvant medical therapy, and reperfusion through primary percutaneous coronary intervention (PCI). While PCI is nowadays first option treatment patients with STEMI, antithrombotic including antiplatelet anticoagulant agents, cornerstone pharmacological to optimize their clinical outcomes. aim this study was describe contemporaneous real-world patterns use...

10.1016/j.repce.2019.02.016 article PT cc-by-nc-nd Revista Portuguesa de Cardiologia (English Edition) 2019-11-01

In patients with acute myocardial infarction (MI), cardiogenic shock (CS), and multivessel disease (MVD) questions remain unanswered when it comes to intervention on non-culprit arteries.This article aims 1) characterize MI, CS MVD included in the Portuguese Registry Acute Coronary Syndromes (ProACS); 2) compare different revascularization strategies sample; 3) identify predictors of in-hospital mortality among these patients.Observational retrospective study ProACS between 2010 2018. Two...

10.36660/abc.20190739 article PT cc-by-nc Arquivos Brasileiros de Cardiologia 2021-05-01

Abstract Introduction Balloon pulmonary angioplasty (BPA) is a complex procedure and not risk free. In an attempt to standardize reports of BPA complications in the several centers, classification was proposed by task force on chronic thromboembolic hypertension (CTEPH) 6th World Symposium Pulmonary Hypertension (WSPH). Purpose To determine prevalence according WSPH identify its predictors. Methods Detailed procedural technical aspects were collected for consecutive patients (pts) with...

10.1093/eurheartj/ehab724.1916 article EN European Heart Journal 2021-10-01

Introduction: Ebstein's anomaly is traditionally described as an isolated of the right valvular apparatus.In last decade, associations with left side anomalies have been described, specifically ventricular non-compaction.More recently, link between this association and presence mutations contractile apparatus proteins has described.Case description: A 34-year-old woman diagnosed since childhood had regular follow-up until 2010.The TTE (2009) describes apical insertion (þ/-25mm;15.4mm/m2 crux...

10.1093/ehjci/jex288 article EN European Heart Journal - Cardiovascular Imaging 2017-12-01
Coming Soon ...