A5024059089- Ultrasound in Clinical Applications
- Hemodynamic Monitoring and Therapy
- Respiratory Support and Mechanisms
- Cardiovascular Function and Risk Factors
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Non-Invasive Vital Sign Monitoring
- COVID-19 Clinical Research Studies
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Effects of Exercise
- Climate Change and Health Impacts
- Cardiac Arrest and Resuscitation
- Acute Ischemic Stroke Management
- Intensive Care Unit Cognitive Disorders
- Radiation Dose and Imaging
- Takotsubo Cardiomyopathy and Associated Phenomena
- Family and Patient Care in Intensive Care Units
- Ultrasound and Hyperthermia Applications
- Ultrasound Imaging and Elastography
- Pleural and Pulmonary Diseases
- Pneumothorax, Barotrauma, Emphysema
- Trauma Management and Diagnosis
- Long-Term Effects of COVID-19
- Emergency and Acute Care Studies
- Autoimmune and Inflammatory Disorders Research
Hospital Garcia de Orta
2013-2025
University of Lisbon
2022-2025
CUF Porto Hospital
2024
Sociedade Portuguesa de Cardiologia
2022
Hospital Militar Central
2020
Bicêtre Hospital
2019
A passive leg raising (PLR) test is positive if the cardiac index (CI) increased by > 10%, but it requires a direct measurement of CI. On oxygen saturation plethysmographic signal, perfusion (PI) ratio between pulsatile and non-pulsatile portions. We hypothesised that changes in PI could predict PLR thus preload responsiveness totally non-invasive way.In patients with acute circulatory failure, we measured (Radical-7) CI (PiCCO2) before during and, decided, after volume expansion (500-mL...
Abstract Background Ventilator-associated pneumonia caused by Pseudomonas aeruginosa (PA) in hospitalised patients is associated with high mortality. The effectiveness of the bivalent, bispecific mAb MEDI3902 (gremubamab) preventing PA nosocomial was assessed PA-colonised mechanically ventilated subjects. Methods EVADE (NCT02696902) a phase 2, randomised, parallel-group, double-blind, placebo-controlled study Europe, Turkey, Israel, and USA. Subjects ≥ 18 years old, ventilated, tracheally...
The admission of COVID-19 patients to the Intensive Care Unit (ICU) is largely dependent on illness severity, yet no standard criteria exist for this decision. Here, lung ultrasound (LU) data, blood gas analysis (BGA), and clinical parameters from venous tests (VBTs) were used, along with machine-learning (ML) models predict need ICU admission. Data fifty-one patients, including status, collected. information LU was gathered through identification findings (LUFs): B-lines, irregular pleura,...
Abstract Background Machine learning algorithms have recently been developed to enable the automatic and real-time echocardiographic assessment of left ventricular ejection fraction (LVEF) not evaluated in critically ill patients. Methods Real-time LVEF was prospectively measured 95 ICU patients with a machine algorithm installed on cart-based ultrasound system. measurements taken by novices (LVEF Nov ) experts Exp were compared reference Ref manually echo experts. Results ranged from 26 80%...
Ultrasound (US) imaging is used in the diagnosis and monitoring of COVID-19 breast cancer. The presence Speckle Noise (SN) a downside to its usage since it decreases lesion conspicuity. Filters can be remove SN, but they involve time-consuming computation parameter tuning. Several researchers have been developing complex Deep Learning (DL) models (150,000–500,000 parameters) for removal simulated added without focusing on real-world application removing naturally occurring SN from original...
Quantitative approaches to improve lung ultrasound (LUS) vertical artifacts (VA) interpretation using total signal intensity (ITOT) are not widely available for clinical practice. In this study, we aimed i) develop a mathematical algorithm extract ITOT as post-hoc LUS analysis and ii) confirm utility by conducting laboratory VA research an in vitro model with different acoustic channels. The was extracted from static conventional imaging recorded models after varying the amount of water...
Abstract Myocardial dysfunction is common in patients admitted to the intensive care unit (ICU). Septic disease frequently results cardiac dysfunction, and sepsis represents most cause of admission death ICU. The association between left ventricular (LV) systolic mortality not clear for critically ill patients. Conversely, LV diastolic (DD) seems increasingly recognized as a factor associated with poor outcomes, only but also more generally Despite recent attempts simplify diagnosis grading...
Hyponatraemia is the most prevalent electrolyte disorder in neurocritical care setting and associated with a significant morbimortality. Cerebral salt wasting inappropriate antidiuretic hormone secretion syndrome have been classically described as two frequent entities responsible for hyponatraemia patients. An accurate aetiological diagnosis of hypotonic requires proper volume status assessment. Nevertheless, determination based on physical examination, laboratory findings imaging...
The aim of the work described here was to analyze relationship between change in ultrasound (US) settings and vertical artifacts' number, visual rating signal intensity METHODS: An vitro phantom consisting a damp sponge gelatin mix created simulate artifacts. Furthermore, several US parameters were changed sequentially (i.e., frequency, dynamic range, line density, gain, power image enhancement) after acquisition. Five experts rated artifacts for number quality. In addition, artifact score...
Lung ultrasound (LUS) is a valuable tool to predict and monitor the COVID-19 pneumonia course. However, influence of cardiac dysfunction (CD) on LUS findings remains be studied. Our objective was determine effect CD in hospitalized patients with pneumonia.Fifty-one participated study. Focused echocardiography (FoCUS) carried out day 1 separate into two groups depending whether they had FoCUS signs (CD+ vs CD-). scores, based thickness pleural line, B-line characteristics, presence or not...
Objectives: Pneumothorax and pneumomediastinum are associated with high mortality in invasively ventilated coronavirus disease 2019 (COVID-19) patients; however, the rates among non-intubated patients remain unknown. We aimed to analyze clinical features of COVID-19-associated pneumothorax/pneumomediastinum identify risk factors for mortality. Methods: searched PubMed Scopus Embase from January 2020 December 2021. performed a pooled analysis 151 no invasive mechanical ventilation history 17...
Reperfusion therapy is generally recommended in acute high-risk pulmonary embolism (HR-PE), but several population-based studies report that it underused. Data on epidemiology, management and outcomes of HR-PE Portugal are scarce.
The number of vertical artefacts (VAs) in lung ultrasound (LUS) impacts patients' clinical management. This study aimed to demonstrate the influence settings on VAs patients under invasive mechanical ventilation (IMV). Patients IMV were recruited for LUS, including three breathing cycles with a motionless curvilinear probe thoracic region most VAs. Three experts LUS asked about at random, and blinded after altering total 20 test recordings per patient. correlation between expert...
This study describes the experience of a reference center using continuous aspiration mechanical thrombectomy for acute high- and intermediate-high-risk pulmonary embolism (PE).Twenty-nine consecutive patients with central PE (48.3% high-risk PE; 82.8% in class >III from original Pulmonary Embolism Severity Index score; median Charlson Comorbidity 4) were treated Indigo® Mechanical Thrombectomy System between March 2018 2020. Technical success was defined as successful placement device...
SARS-CoV-2 infection is associated with multiple cardiac manifestations. Left atrial strain (LA-S) by speckle tracking echocardiography (STE) a novel transthoracic (TTE) measure of LA myocardial deformation and diastolic dysfunction, which could lead to early recognition injury in severe COVID-19 patients possible implications on clinical management, organ mortality. Cardiac may occur direct viral cytopathic effects or virus-driven immune activation, resulting heart infiltration inflammatory...
COVID-19 represents a global health emergency, causing significant morbidity and mortality. Multiple vaccines have been distributed worldwide to control the spread of this pandemic. Several reports thrombosis thrombocytopaenia described after vaccination. These termed vaccine-induced immune (VITT). We report fatal case VITT receiving first dose Ad26.COV2.S vaccine. A man in his 30s developed thrombocytopaenia, massive haemoperitoneum due spleen rupture extensive portal femoral vein...
Abstract: Ultrasound technology is an essential tool in the management of critically ill patients. Point-of-care ultrasonography (POCUS) enables data collection from different anatomic areas to achieve most probable diagnosis and administer right therapy at time. Despite increasing utilization POCUS, there still a lack standards establish how use bedside ultrasound protocols, it imperative develop unifying protocol. Thus, aim this paper new systematized approach that can be adopted by all...
A 24-year-old man presented to the emergency department with fever, maculopapular rash, myalgia and polyarthralgia, thoracic pain dry cough, which had been present for 24 h. At time of observation he high fever (39°C), rash on torso, arms legs proximally, axillary adenopathies pharyngitis. Laboratorial data showed elevated inflammation markers (leukocytosis, C reactive protein 44 mg/dL, erythrocyte sedimentation rate 120 mm), transaminases, lactate dehydrogenase, ferritin levels (>2000...