A5054797240- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Adipose Tissue and Metabolism
- Animal Nutrition and Physiology
- Erythropoietin and Anemia Treatment
- Inflammatory Bowel Disease
- Fatty Acid Research and Health
- Microscopic Colitis
- Aquaculture Nutrition and Growth
- Adipokines, Inflammation, and Metabolic Diseases
- Algal biology and biofuel production
- Phytochemicals and Antioxidant Activities
- Exercise and Physiological Responses
- Organ Transplantation Techniques and Outcomes
- Antioxidant Activity and Oxidative Stress
- Meat and Animal Product Quality
- Liver Disease Diagnosis and Treatment
- Gut microbiota and health
- Cancer, Lipids, and Metabolism
- Lysosomal Storage Disorders Research
- Nitric Oxide and Endothelin Effects
- Eicosanoids and Hypertension Pharmacology
- Cardiac Ischemia and Reperfusion
- Retinopathy of Prematurity Studies
- Essential Oils and Antimicrobial Activity
Rede de Química e Tecnologia
2022-2025
Universidade Federal do ABC
2025
University of Lisbon
2014-2024
Ordem dos Médicos
2020-2024
Hospital de Clínicas
2019
Polytechnic Institute of Portalegre
2019
Faculdade Meridional
2019
Escola Superior de Saúde Egas Moniz
2018
Hospital de São João
2017
Hospital de Santo António
2017
Rosmarinic acid is a polyphenolic compound and main constituent of Rosmarinus officinalis has been shown to possess antioxidant anti-inflammatory properties. We aimed evaluate the properties rosmarinic an extract R. in local inflammation (carrageenin-induced paw oedema model rat), further protective effect rat models systemic inflammation: liver ischaemia-reperfusion (I/R) thermal injury models. In model, was administered at 10, 25 50 mg/kg (p.o.), 10 (equivalent doses groups) male Wistar...
The purpose of this paper is to evaluate the chronic effect sitagliptin on metabolic profile, inflammation, and redox status in Zucker Diabetic Fatty (ZDF) rat, an animal model obese type 2 diabetes. ZDF ( fa/fa ) rats their controls (ZDF +/+) were treated during 6 weeks with vehicle (control) (10 mg/kg/bw). Glucose, HbA1c, insulin, Total-c, TGs, IL-1<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mi>β</mml:mi></mml:math>, TNF-<mml:math...
Abstract The antihyperglycaemic effect of eight standard flavonoids, previously identified in the ethanol extract claimed antidiabetic plant Genista tenera , was evaluated on streptozotocin (STZ)‐induced diabetic Wistar rats. aglycones apigenin, chrysoeriol and genistein, monoglucosides apigenin 7‐ O ‐glucoside, luteolin ‐glucoside genistein diglycosides rutin 7,3′‐di‐ were administered i.p. for 7 days (4 mg/kg b.w./day). protective these compounds over liver kidneys STZ–diabetic models also...
This study assessed the effect of Spirulina (Arthrospira platensis), individually and in combination with exogenous enzymes, on growth performance, carcass traits, meat quality broiler chickens. One hundred twenty Ross 308 male chickens were allocated into 40 battery brooders, 3 birds per cage, fed ad libitum a corn-based diet during first 21 D trial. The experimental period lasted from day to 35, which 4 different diets: corn-soybean basal diet, taken as control group, containing 15% (MA),...
The regular intake of tomatoes or its products has been associated with a reduced risk chronic diseases and these effects have mainly attributed to lycopene. Here, we evaluated the anti-inflammatory properties lycopene protective on organ injury in two experimental models inflammation. In order study local inflammation, carrageenan-induced paw oedema model rats was performed. Lycopene administered as an acute (1, 10, 25 50 mg/kg, intraperitoneally, 15 min before carrageenan injection)...
The aim of this study is to evaluate the effect gender and menopause in cardiometabolic risk a type 2 diabetes mellitus (T2DM) population, based on classical non-traditional markers.Seventy four volunteers 110 T2DM patients were enrolled study. Anthropometric data, blood pressure, body mass index (BMI), waist circumference (WC) following serum markers analyzed: glucose, Total-c, TGs, LDL-c, Oxidized-LDL, total HDL-c large small subpopulations, paraoxonase 1 activity, hsCRP, uric acid, TNF-α,...
Persimmon (Diospyros kaki L.), a fruit rich in phenolic compounds (PCs), has been considered effective mitigating oxidative damage induced by an excess of reactive oxygen species. Due to large molecular weight and intrinsic instability some physiological fluids, PCs' passage through biological membranes is very limited. Carriers like phytosomes are promising systems optimize oral absorption encapsulated extracts. This work prepared fully characterized containing bioactive extracts from...
Aerogel scaffolds are nanostructured materials with beneficial properties for tissue engineering applications. The tracing of the state aerogels after their implantation is challenging due to variable biodegradation rate and lack suitable strategies capable
This study compares the effects of a single bout exercise (acute extenuating) with those promoted by an training program (chronic), focusing on low-grade chronic inflammation profile and oxidative stress status, using obese ZDF rats as model type 2 diabetes mellitus (T2DM). Animals were sacrificed after 12 weeks swimming acute extenuating exercise. Glycaemic, insulinemic, lipidic (triglycerides, total-cholesterol) evaluated, well inflammatory (serum CRP hs , TNF-α, adiponectin) (lipidic...
Background: Inflammatory bowel disease (IBD) is a world healthcare problem. In order to evaluate the effect of new pharmacological approaches for IBD, we aim develop and validate chronic trinitrobenzene sulfonic acid (TNBS)-induced colitis in mice. Methods: Experimental was induced by rectal administration multiple doses TNBS female CD-1 The protocol performed with six experimental groups, depending on frequency, two control groups (sham ethanol groups). Results: survival rate 73.3% first...
The impact of 15% dietary inclusion Spirulina ( Arthrospira platensis ) in broiler chickens was explored, focusing on blood cellular components, systemic metabolites and hepatic lipid mineral composition. From days 14 to 35 age, 120 were divided allocated into four treatments: a standard corn soybean meal-based diet (control), diet, extruded super-dosed with an enzyme blend (0.20% porcine pancreatin plus 0.01% lysozyme). haematological analysis revealed no significant deviations p &gt;...
Background/Objectives: Retinopathy of prematurity (ROP) is a leading cause vision impairment in preterm infants, with its pathogenesis linked to oxygen exposure. Red blood cell (RBC) transfusions, commonly performed neonatal intensive care units (NICUs), reduce fetal hemoglobin (HbF) fraction, altering dynamics and potentially contributing ROP. We aimed investigate the relationship between RBC HbF percentage, ROP, evaluating as potential predictive biomarker. Methods: A multicenter,...