José Luis Guil‐Guerrero

ORCID: 0000-0003-2666-1774
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Fatty Acid Research and Health
  • Lipid metabolism and biosynthesis
  • Aquaculture Nutrition and Growth
  • Cholesterol and Lipid Metabolism
  • Phytochemicals and Antioxidant Activities
  • Antioxidant Activity and Oxidative Stress
  • Edible Oils Quality and Analysis
  • Plant biochemistry and biosynthesis
  • Algal biology and biofuel production
  • Food Chemistry and Fat Analysis
  • Insect Utilization and Effects
  • Enzyme Catalysis and Immobilization
  • Meat and Animal Product Quality
  • Natural Products and Biological Research
  • Natural product bioactivities and synthesis
  • Pleistocene-Era Hominins and Archaeology
  • Nuts composition and effects
  • Essential Oils and Antimicrobial Activity
  • Adipose Tissue and Metabolism
  • Indigenous Studies and Ecology
  • Botanical Research and Applications
  • Phytochemical Studies and Bioactivities
  • Diet and metabolism studies
  • Animal Nutrition and Physiology
  • Analytical Chemistry and Chromatography

University of Almería
2016-2025

Instituto de Tecnologia de Alimentos
2006

Universidad Complutense de Madrid
1996

The 5xFAD transgenic mouse model widely used in Alzheimer’s disease (AD) research recapitulates many AD-related phenotypes with a relatively early onset and aggressive age-dependent progression. Besides developing amyloid peptide deposits alongside neuroinflammation by the age of 2 months, as well exhibiting neuronal decline 4 months that intensifies 9 these mice manifest broad spectrum behavioural impairments. In this review, we present extensive repertoire dysfunctions mice, organised into...

10.3390/ijms25126766 article EN International Journal of Molecular Sciences 2024-06-20

Abstract Stearidonic acid (SA, 18:4 n ‐3) is a polyunsaturated fatty (PUFA) that constitutes the first metabolite of α‐linolenic (ALA, 18:3 in metabolic pathway leading to C 20–22 PUFA, such as eicosapentaenoic (EPA, 20:5 ‐3), and docosahexaenoic (DHA, 22:6 which recently have received much attention because their various physiological functions human body. Recently, several studies indicated dietary SA increased EPA more efficiently than ALA. Thus, vegetable oils containing may become...

10.1002/ejlt.200700207 article EN European Journal of Lipid Science and Technology 2007-12-01

Alzheimer’s disease (AD), the leading cause of dementia, presents a significant global health challenge with no known cure to date. Central our understanding AD pathogenesis is β-amyloid cascade hypothesis, which underlies drug research and discovery efforts. Despite extensive studies, animal models have completely validated this hypothesis. Effective are essential for accurately replicating key pathological features disease, notably formation plaques neurofibrillary tangles. These markers...

10.3390/ijms25052805 article EN International Journal of Molecular Sciences 2024-02-28

The nutritional composition of the marine eustigmatophyte Nannochloropsis spp. cultured in an indoor chemostat under continuous illumination was analyzed. Proximate composition, (moisture, ash, crude protein, available carbohydrates, fiber, lipids, and energy), nitrate, nucleic acid, mineral element (Na, K, Ca, Mg, Fe, Cu, Zn, Mn, Pb, Cd, Cr, Ni, Co, S), fatty pigment (carotenoids chlorophyll) concentrations were determined. On average, biomass contained 37.6% (w/w) 28.8% 18.4% total lipids....

10.1021/jf0010376 article EN Journal of Agricultural and Food Chemistry 2001-05-10

Alzheimer’s disease (AD) is the most common cause of dementia, and no cure currently available. The β-amyloid cascade AD neurofibrillary tangles are basis current understanding pathogenesis, driving drug investigation other discoveries. Up until now, models have entirely validated hypothesis. must be capable recapitulating critical events this pathology, including plaques tangles. development probably derived from amyloid precursor protein (APP) presenilin 1 (PS1) familial (FAD) mutations,...

10.3390/jdad2010002 article EN Journal of dementia and Alzheimer's disease 2025-01-10

The contents of oxalic acid and calcium in several wild edible plants were analyzed. Oxalic was determined by an espectrophotometric method based on the decrease absorbance at 335 nm due to dissociation zirconium(IV)−chloranilate complex, consecutive addition acid. Calcium atomic absorption spectroscopy. results show absence this two studied plants: hoary cress (Cardaria draba (L.) Desv.) vervain (Verbena officinalis L.). Also noticeable is high content goosefoot (Chenopodium album L.), with...

10.1021/jf950472a article EN Journal of Agricultural and Food Chemistry 1996-01-01

Abstract Forty‐nine plant species from Spain, belonging to the Boraginaceae, Scrophulariaceae, Onagraceae, and Ranunculaceae families, were surveyed in a search of new sources γ‐linolenic acid (18∶3ω6, GLA). Fatty profiles seeds, stems, roots, flowers leaves determined. GLA was detected mainly seed root tissues. High amounts found seeds Boraginaceae species, with maximum 20.25% total fatty acids Myosotis nemorosa . Within Scrophulariaceae highest content (10.17%) Scrophularia sciophila...

10.1007/s11746-001-0325-9 article EN Journal of the American Oil Chemists Society 2001-07-01
Coming Soon ...