A5010288519- Neuroscience and Neural Engineering
- Advanced Topics in Algebra
- RNA Interference and Gene Delivery
- Gut microbiota and health
- Neuroinflammation and Neurodegeneration Mechanisms
- MicroRNA in disease regulation
- Clostridium difficile and Clostridium perfringens research
- Adenosine and Purinergic Signaling
- Gastrointestinal motility and disorders
- Mesenchymal stem cell research
- Nonlinear Waves and Solitons
- Neuroscience and Neuropharmacology Research
- Algebraic structures and combinatorial models
- Restless Legs Syndrome Research
- Neurological Complications and Syndromes
University of Verona
2020-2024
Politecnico di Milano
2010
The purinergic ATP-gated P2X7 receptor (P2X7R) is increasingly recognized to contribute pathological neuroinflammation and brain hyperexcitability. P2X7R expression has been shown be increased in the brain, including both microglia neurons, experimental models of epilepsy patients. To date, cell type-specific downstream effects P2X7Rs during seizures remain, however, incompletely understood.
A bulk of data suggest that the gut microbiota plays a role in broad range diseases, including those affecting central nervous system. Recently, significant differences intestinal patients with epilepsy, compared to healthy volunteers, have been reported an observational study. However, active pathogenesis through so-called "gut-brain axis," has yet be demonstrated. In this study, we evaluated direct impact transplanted from epileptic animals recipient animals, clarify whether epilepsy can...
We study classes of indecomposable representations the Diamond Lie algebra: a four-dimensional solvable algebra, which is central extension Poincaré algebra in two dimensions. These are obtained first (inspired by Douglas and Premat [Commun. Algebra 35, 1433 (2007)]) embedding simple algebras A2 C2, then regarding it as subalgebra truncated current algebra.
In animal models of epilepsy, cranial surgery is often required to implant electrodes for electroencephalography (EEG) recording. However, electrode implants can lead the activation glial cells and interfere with physiological neuronal activity. this study, we evaluated impact epidural in pilocarpine mouse model temporal lobe epilepsy. Brain neuroinflammation was assessed 1 3 weeks after by cytokines quantification, immunohistochemistry, western blotting. Moreover, investigated effect...