- Bone fractures and treatments
- Orthopedic Surgery and Rehabilitation
- Muscle and Compartmental Disorders
- Connective Tissue Growth Factor Research
- Hip disorders and treatments
- Orthopaedic implants and arthroplasty
- Musculoskeletal pain and rehabilitation
- Safety Systems Engineering in Autonomy
- COVID-19 Clinical Research Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Cardiac Valve Diseases and Treatments
- Traffic and Road Safety
- Hip and Femur Fractures
- Injury Epidemiology and Prevention
- Bone and Joint Diseases
- Amoebic Infections and Treatments
- MicroRNA in disease regulation
- Bone health and treatments
- Rabies epidemiology and control
- Pneumothorax, Barotrauma, Emphysema
- Blood transfusion and management
- Diverse Scientific Research Studies
- Lower Extremity Biomechanics and Pathologies
Federal Ministry of Health
2024
King George's Medical University
2012-2021
North Bengal Medical College and Hospital
2021
Creative Commons
2021
All India Institute of Medical Sciences Bhopal
2018
All India Institute of Medical Sciences Raipur
2018
All India Institute of Medical Sciences
2018
Sir Ganga Ram Hospital
2018
Bahawal Victoria Hospital
2018
Abbott (India)
2017
Triage at emergency department is performed to identify those patients who are relatively more serious and require immediate attention treatment. Despite current methods of triage, trauma continues be a leading cause morbidity mortality.This study was evaluate the predictive value shock index (SI) modified (MSI) for hospital mortality among adult patients.In this prospective longitudinal study, all sustained enrolled as per inclusion/exclusion criteria. After collection data, SI MSI were...
We aimed to analyse the frequency and patterns of fall-related injuries presenting emergency departments (EDs) across Pakistan. Pakistan National Emergency Departments surveillance system collected data from November 2010 March 2011 on a 24/7 basis using standardized tool in seven major EDs (five public two private hospitals) six cities For all patients with injuries, we analysed by intent focus unintentional falls. Simple frequencies were run for basic patient demographics, mechanism falls,...
Aims: The aim of this study is to analyze the serial estimation phosphorylated neurofilament heavy (pNF-H) in blood plasma that would act as a potential biomarker for early prediction neurological severity acute spinal cord injuries (SCI) adults.Settings and Design: Pilot study/observational study.Subjects Methods: A total 40 patients (28 cases 12 controls) spine injury were included study. In enrolled cases, level pNF-H was evaluated samples evaluation performed by American Spinal Injury...
Background . Hip distraction in Perthes’ disease unloads the joint, which negates harmful effect of stresses on articular surfaces, may promote sound healing area necrosis. We have examined arthrodiastasis preservation femoral head older children with disease. Methods and Materials Twelve age more than 8 years less one year were treated hip by a hinged monolateral external fixator. Observation Results Mean duration was 13.9 days. These evaluated clinicoradiological parameters for mean period...
Helmet, as a protective gear to prevent fatal injuries while riding two-wheelers, needs be evaluated by quality data. The aim of the study was find out spectrum sustained with downstream outcomes in relation acceptable ways use crash-proof helmet among motorized two-wheeler riders compared nonuse following road traffic accidents. present an analytical cross-sectional multicentric conducted at three dedicated trauma care centers India: (a) Jai Prakash Narayan Apex Trauma Center, All India...
Background . Many factors are responsible for this impaired healing, especially in long bones, but a possible genetic predisposition the development of complication remains unknown till now. In present study, we aim to examine CYR61 gene polymorphism fracture nonunion patients and correlation with clinical findings. Materials Methods We performed SNP analysis 250 healthy subjects were genotyped hospital-based case control 56 cases further evaluated mRNA expression by real-time quantitative...
Background: This retrospective study examined the effectiveness and safety of polygeline in adult patients with hypovolemia due to traumatic injury. Materials Methods: Polygeline was administered after evaluating amount blood loss estimating hematological biochemical parameters. Changes vital signs, serum electrolytes, arterial pH, lactate were evaluated. The evaluated by recording adverse events if any. Results: Sixty mean age 37.5 ± 11.26 years included study. All had < 20%. total 1025.0...
Angiogenesis is a prerequisite for fracture repair, whereas insufficient blood supply likely to result in impaired healing. In the present study, we aimed determine correlation of simple tibial healing outcome with serial estimation CYR61 expressions early phase healing.In total, 107 adult fractured patients and 97 healthy controls were analysed. Peripheral samples taken from (at once) at 4th, 7th, 10th, 15th, 20th 28th days post-fracture follow-ups quantify mRNA protein expression by...
Objective: To compare correct assessment of gestational age betweenTranscerebeller diameter versus femur length in third trimester (28-40) using first day lastmenstrual period for actual gestation. Study Design: Cross-sectional descriptive study.Place and Duration Study: Department Obstetrics Gynecology, Bahawal VictoriaHospital, Bahawalpur from Jun 2012 to Dec 2012. Methodology: This study was performed on327 patients pregnancy 28-40 weeks fulfilling the inclusion criteria.Ultrasound...
<p class="BodyText1">Osteosarcoma is the most common type of bone cancer, which appears mainly<strong> </strong>in metaphysis long bones, especially in males between age 0–14 years. Malignancy usually emerges with abnormal growth tumor-forming cells. These tumor cells act like new bones that are responsible for spread sarcoma throughout matrix. In this review, we focused on expression and function P2X7 receptor (<em>P2X7R</em>) as a therapeutic target...
There is a current public health issue threatening human worldwide with the rapid spread of novel coronavirus (2019‑nCoV) or severe acute respiratory syndrome coronavirus‑2 (SARS‑CoV‑2). The infection was reported to first originate in bats and subsequently humans via yet unknown source animals Wuhan, Hubei, China December, 2019. Coronavirus disease 2019 (COVID‑19) caused by extreme (SARS‑CoV‑2) an unprecedented healthy global emergency. outbreak SARS‑CoV‑2 has once again revealed...
The coronavirus disease 2019 (COVID-19) emerged in China late with high rate of spread and transmission. As there was no recognized therapy many people worldwide used herbs attempt to help their body overcome the disease.
Hepatitis B virus (HBV) is a significant global health concern, requiring deeper understanding of its replication and pathogenic mechanisms to develop effective therapies. This study investigated the transcription efficiency, antigen dynamics, virion production wild-type HBV (wtHBV) defective (dHBV) constructs. The levels dHBV prRNA were 2.5 times higher in Sample 1 than 2. They 2.8 (p < 0.01) 2, even though cccDNA same both samples > 0.25 for p 0.16 2). amount improved considerably,...
Osteosarcoma requires an angiogenesis process. CYR61 is one of the extracellular signaling molecules that promote angiogenesis, tumor growth, and malignancy osteosarcoma. In present study, we investigate gene variations in osteosarcoma their correlations with clinicopathological findings.We performed variation analysis 58 patients With aim to ascertain variety exons 2, 3, 4, 5 osteosarcoma, did a PCR-SSCP followed by DNA sequencing.In found were 18.96% (11/58) exon 3.44% (2/58) 8.62% (5/58)...
Introduction. The treatment of long bone shaft nonunions is challenging. technique osteoperiosteal decortications flap for approaching the nonunion site coupled with fixation modalities was first described by Judet in 1963. Despite promising clinical and radiological union, this not popular among orthopaedic surgeons. Our study aimed to evaluate union functional results tibia treated decortication approach. Methods. This retrospective included all cases established tibial following stringent...
Background: Clubfoot is a developmental deformity stirring at ankle, sub-taloid, and metatarsal joints. This includes three elements: the foot inversion; forefoot-adduction relative to hindfoot; equinus position. The need for this case study was understand effectiveness of various treatment/management programs. Methodology: performed relating severity congenital talipes equinovarus (CTEV) with Achilles tendon tenotomy (ATT) in management along demographic parameters. Overall, 95 patients...
Abstract Presentation of metastasis as a solitary focal lesion at an intravascular location is encountered quite infrequently. Owing to its location, accessing the for sampling and obtaining adequate amount tissue are technically difficult. Among various methods sample from lesions, scoop trucut biopsies appear be safer more advantageous. The authors present case 65-year-old woman with symptoms superior vena cava syndrome secondary fluorodeoxyglucose (FDG)–avid thrombus within lumen 14 years...
The aim of this study was to analyze the clinical signs diagnosis, treatment and followupof pediatric population presenting with acute compartment syndrome in theemergency room at an Institutional Level II trauma center. is a prospective caseseries. Thirty-two samples were selected from Trauma Centre, King George’sMedical University, Lucknow, between January 2005 December 2010. Childrenpresenting clinically suspected studied. Thesewere divided into two age related groups: Group A (children...
Background & Objectives: Vascular endothelial growth factor (VEGF) plays an important role in the bone repair process by acting as a potent mediator of angiogenesis. In present study, we aim to analyse temporal expression serum VEGF during early phase fracture healing and further correlate it with outcomes. Methods: this longitudinal cohort per inclusion- exclusion criteria, total 76 adult patients simple, fresh traumatic diaphyseal fractures both bones leg managed conservatively; were...