A5019648783- Food composition and properties
- Microbial Metabolites in Food Biotechnology
- Polysaccharides Composition and Applications
- Proteins in Food Systems
- Phytase and its Applications
- GABA and Rice Research
- Legume Nitrogen Fixing Symbiosis
- Microencapsulation and Drying Processes
- Cancer-related molecular mechanisms research
- Nanoparticle-Based Drug Delivery
- Enzyme Production and Characterization
- RNA modifications and cancer
- Caveolin-1 and cellular processes
- Flavonoids in Medical Research
- Cardiovascular Disease and Adiposity
- Food Quality and Safety Studies
- Pluripotent Stem Cells Research
- Bioactive Compounds in Plants
- Cellular Mechanics and Interactions
- Plant nutrient uptake and metabolism
- Nematode management and characterization studies
- Nanocomposite Films for Food Packaging
- Plant Disease Resistance and Genetics
- Plant responses to water stress
- interferon and immune responses
Korea Food Research Institute
2019-2024
University of Chicago
2024
Children's Cancer Center
2020-2022
Baylor College of Medicine
2020-2022
Seoul National University
2015-2021
University of Central Arkansas
2018-2020
Conway School of Landscape Design
2018-2020
St. Jude Children's Research Hospital
2017
Major non-legume crops can form beneficial associations with nitrogen-fixing bacteria like Azospirillum brasilense. Our current understanding of the molecular aspects and signaling that occur between important rice these is limited. In this study, we used an experimental system where could colonize plant roots promote growth in wild type symbiotic mutants (dmi3 pollux) rice. data suggest promotion root penetration not dependent on genes. We then colonization model to identify regulation gene...
Abstract Peptide and protein nanostructures with tunable structural features, multifunctionality, biocompatibility biomolecular recognition capacity enable development of efficient targeted drug delivery tools for precision medicine applications. In this review article, we present various techniques employed the synthesis self‐assembly peptides proteins into nanostructures. We discuss design strategies utilized to enhance their stability, drug‐loading capacity, controlled release properties,...
Resistant starch serves as a prebiotic in the large intestine, aiding maintenance of healthy intestinal environment and mitigating associated chronic illnesses. This study aimed to investigate impact resistant starch-enriched brown rice (RBR) on health functionality. We assessed changes concentration, structural alterations, branch chain length distribution throughout digestion process using an vitro model. The efficacy RBR was evaluated through analyses its potential, effects microbiota,...
We investigated dual modification of normal and waxy rice starch, focusing on digestibility. Amylosucrase (AS) was applied to maximize the slowly digestible resistant starch fractions. AS-modified starches were adjusted 25-40% moisture levels heated at 100 °C for 40 min. exhibited a B-type crystalline structure, hydrothermal treatment (HTT) significantly (p < 0.05) increased relative crystallinity with level. The thermal transition properties modified also affected by contents rapidly...
In this study, the effects of sonication and temperature-cycled storage on structural properties resistant starch content high-amylose corn were investigated. Sonication induced a partial depolymerization molecular structures amylopectin amylose. treatment appropriate changes for retrogradation. Although relative crystallinity sonicated was lower than that non-sonicated starch, after retrogradation showed much higher starch. Regardless treatment, resulted in degree isothermal storage, but...
Dietary supplementation with indigestible carbohydrates is known to improve the gut environment and prevent obesity inflammatory diseases by modulating microbiota. In previous work, we established a method for production of resistant starch (RS)-enriched high-amylose rice (R-HAR) using citric acid. The present study aimed evaluate changes in structural characteristics during digestion R-HAR its effects on health. A three-step vitro fermentation model was used, then, RS content, scanning...
Ponatinib (Pon) is a multi-tyrosine kinase inhibitor that demonstrated high efficiency for treating cancer. However, severe side effects caused by Pon off-targeting prevent its extensive use. Using our understanding into the mechanisms which transported bovine serum albumin in blood, we have successfully encapsulated biomimetic nanoparticle (NP). This lipid NP (i.e., "leukosomes") incorporates membrane proteins purified from activated leukocytes enable immune evasion, and enhanced targeting...
Abstract Endothelial tissues are essential mechanosensors in the vasculature and facilitate adaptation to various blood flow-induced mechanical cues. Defects endothelial mechanoresponses can perturb tissue remodelling functions leading cardiovascular disease progression. In this context, precise mechanisms of contributing normal diseased functioning remain elusive. Here, we sought uncover how flow-mediated transcriptional regulation drives healthy atherosclerotic-prone tissues. Using bulk...
Abstract Background and objectives With the interest in increasing resistant starch (RS) of cooked rice, lowering its digestibility has been attempted but not established yet. Herein, we aimed to develop a simple cost‐effective method prepare RS‐enriched rice. Various combinations rice types, cooking methods, additives were investigated increase RS content. Findings The high‐amylose cultivar (~28% amylose), retort‐type (121°C, 30 min, 15 psi), brown resulted higher content than that normal...
Abstract In this study, starch–lipid complexes were prepared using normal corn starch (NC) and amylosucrase‐modified waxy (ASWC) with myristic acid (C14:0) palmitic (C16:0). The amylosucrase modification elongated branch chains in leading to an increase of apparent amylose content (29.7%) similar that NC (29.0%). X‐ray diffraction revealed a V‐type pattern, clear indication complex formation. ability the ASWC fatty acids was greater than NC. Interestingly, changes relative crystallinity,...
This study investigated the structural and physicochemical characteristics of malic acid-treated sweet potato starch. Sweet starch mixed with various concentrations acid solution underwent either thermal or nonthermal treatment. Observation samples under a light microscope ensured maintenance granular shape Maltese cross. FT-IR spectra displayed distinct carbonyl peak at 1722 cm −1 , analysis degree substitution (DS) indicated an increase in extent ester bonds increasing acid. The DS...
The effects of immersion time on the physicochemical properties and resistant starch (RS) formation malic acid-treated rice were investigated. Malic acid treatment decreased frequency cracks within kernel. color (lightness) was significantly affected by time, reflecting browning rice. degree substitution gradually increased with reached a plateau after 12 h, intensity C=O bond peak detected in Fourier-transform infrared spectroscopy showed similar trend. However, crystallinity as increased,...
Summary Amylosucrase (AS) modification of starch increases the slowly digestible (SDS) and resistant (RS) fractions. However, characteristics formation mechanism each fraction AS‐modified have not been determined yet. Therefore, this study isolated SDS and/or RS from waxy corn starches investigated their structural characteristics. The amount SDS+RS had a positive correlation with proportion medium length (13–24 degree polymerisation) branched chains amylopectin. relative crystallinity...