A5064682071- Glycosylation and Glycoproteins Research
- Genetic and phenotypic traits in livestock
- Advanced Proteomics Techniques and Applications
- Monoclonal and Polyclonal Antibodies Research
- Identification and Quantification in Food
- Probiotics and Fermented Foods
- Analytical Chemistry and Chromatography
- Protein purification and stability
- Cancer Research and Treatments
- Metabolomics and Mass Spectrometry Studies
- Listeria monocytogenes in Food Safety
- Livestock Management and Performance Improvement
- Extracellular vesicles in disease
- Hepatitis C virus research
- Mycotoxins in Agriculture and Food
- Mass Spectrometry Techniques and Applications
- Crystallization and Solubility Studies
- Air Quality Monitoring and Forecasting
- interferon and immune responses
- Salmonella and Campylobacter epidemiology
- Vehicle emissions and performance
- X-ray Diffraction in Crystallography
- Bacillus and Francisella bacterial research
- Law, AI, and Intellectual Property
- GDF15 and Related Biomarkers
University of Osijek
2014-2024
Rhode Island Hospital
2012-2018
Providence College
2012-2016
Brown University
2012
The mannose receptor (MR, CD 206) is an endocytic primarily expressed by macrophages and dendritic cells, which plays a critical role in both endocytosis antigen processing presentation. MR carbohydrate recognition domains (CRDs) exhibit high binding affinity for branched linear oligosaccharides. Furthermore, multivalent presentation on the various templates like peptides, proteins, polymers, micelles, dendrimers was proven to be valuable approach selective efficient delivery of...
Microgreens are young, immature vegetables that contain higher concentrations of active compounds compared to mature and seeds. Radish microgreens a good source antioxidants, phenolic compounds, ascorbic acid, carotenoids, anthocyanins. The production is limited by their short shelf life due dark respiration accelerated senescence. study was performed on three radish cultivars (Raphanus sativus L.): purple (cvP), red (cvR), green (cvG). were grown in chambers with controlled conditions (24...
A distinct feature of human prostate cancer (PCa) is the development osteoblastic (bone-forming) bone metastases. Metastatic growth in supported by factors secreted PCa cells that activate signaling networks tumor microenvironment augment growth. To better understand these and identify potential targets for therapy metastases, we characterized secretome a patient-derived xenograft, MDA-PCa-118b (PCa-118b), generated from lesion. PCa-118b induces tumors when implanted either mouse femurs or...
Industrial hemp is a fast-growing, short-day plant, characterized by high biomass yields and low demands for cultivation. To manipulate growth, usually cultivated under prolonged photoperiods or continuous light that could cause photooxidative damage adjustments of photosynthetic reactions. determine the extent changes in response caused exposure, we employed chlorophyll fluorescence measurements accompanied with level lipid peroxidation (TBARS) FT-IR spectroscopy on two Cannabis cultivars....
Soybean (Glycine max (L.) Merr.) is one of the most economically important crops in world due to its nutritional value. To optimize soybean growth and yield, a wide range commercial herbicides intended for weed control are used. Although used selective, they can still cause oxidative stress disturb photosynthetic reactions crops. In this work, influence selective on efficiency antioxidative response two cultivars was investigated. The parameters describing performance were derived by...
Sample displacement chromatography ( SDC ) in reversed‐phase and ion‐exchange modes was introduced approximately 20 years ago. This method first used for the preparative purification of peptides proteins. Recently, mode also successfully enrichment low‐abundance proteins from human plasma. In this paper, use separation plasma hydrophobic interaction is demonstrated. By two or more columns coupled series during sample application, subsequent elution detached parallel, additional bound...
Fast, cost-effective and reproducible isolation of IgM from plasma is invaluable to the study subsequent understanding human immune system. Additionally, vast amounts information regarding physiology disease can be derived analysis low abundance proteome plasma. In this study, methods were optimized for both high-throughput plasma, fractionation proteins.To optimize chromatographic many variables examined including chromatography resin, mobile phases, order separations. Purification was...
We examined proteomic profiles of rat liver extracellular vesicles (EVs) shed following treatment with a sub-toxic dose (500 mg/kg) the pain reliever drug, acetaminophen (APAP). EVs representing entire complement hepatic cells were isolated after perfusion intact and analyzed LC-MS/MS. The investigation was focused on revealing function cellular origin identified proteins by different parenchymal non-parenchymal their possible role in an early response this organ to toxic environment....
Abstract Ion‐exchange chromatography is still one of the most popular protein separation techniques. Before chromatographic separation, high salt concentration in various samples necessitates additional steps. Therefore, low tolerance ion‐exchange resins a drawback that needs to be addressed. Herein, differences and hydrophobicity strong cation‐exchange TOYOPEARL sulfonium sulfate‐types were investigated. Despite only minor structural difference, selectivity between sulfate sulfonic groups...
Abstract To identify changes in extracellular vesicles (EVs) secreted by the liver following drug‐induced injury (DILI), rats were treated with a subtoxic dose (500 mg/kg) of analgesic drug, acetaminophen (APAP). EVs collected perfusion sham and APAP‐treated rats. Changes morphology examined transmission electron microscopic analysis negatively stained vesicles. Results from morphometric revealed striking differences their size distribution. Proteome composition was determined mass...
Food borne pathogens, namely the Gram-positive bacterium Bacillus subtilis and Gram-negative Escherichia coli, were grown under inhibition with four different disinfectants based on chloride bromide salts of pyridinium oxime. Bacterial samples subjected to sequential extraction proteins in-solution tryptic digestion obtained extracts was performed prior identification LC-ESI-MS/MS. Proteomic analysis identified up- down-regulated in these bacteria after treatment each compound. The tables...