- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- Global Cancer Incidence and Screening
- AI in cancer detection
- MRI in cancer diagnosis
- Digital Radiography and Breast Imaging
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Cancer and Skin Lesions
- Breast Implant and Reconstruction
- Colorectal Cancer Screening and Detection
- Ultrasound Imaging and Elastography
- Salivary Gland Tumors Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- BRCA gene mutations in cancer
- Cancer Risks and Factors
- Photoacoustic and Ultrasonic Imaging
- Lung Cancer Diagnosis and Treatment
- Cervical Cancer and HPV Research
- Advanced Breast Cancer Therapies
- Soft tissue tumor case studies
- Radiation Dose and Imaging
- Cancer Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Ultrasound and Hyperthermia Applications
University of Pittsburgh
2016-2025
University of Pittsburgh Medical Center
2016-2025
Magee-Womens Hospital
2015-2024
NYU Langone Health
2021
Historic Deerfield
2019
University of Illinois Urbana-Champaign
2019
Breast Center
2019
Florida College
2019
University of Florida
2019
Cedars-Sinai Medical Center
2019
Screening ultrasound may depict small, node-negative breast cancers not seen on mammography.To compare the diagnostic yield, defined as proportion of women with positive screen test results and reference standard, performance screening plus mammography vs alone in at elevated risk cancer.From April 2004 to February 2006, 2809 women, least heterogeneously dense tissue 1 quadrant, were recruited from 21 sites undergo mammographic physician-performed ultrasonographic examinations randomized...
PURPOSE: To prospectively assess accuracy of mammography, clinical examination, ultrasonography (US), and magnetic resonance (MR) imaging in preoperative assessment local extent breast cancer. MATERIALS AND METHODS: Institutional review board approval informed patient consent were obtained. Results bilateral US, contrast-enhanced MR analyzed from 111 consecutive women with known or suspected invasive correlated histopathologic findings. RESULTS: Analysis included 177 malignant foci 121...
Breast Imaging Reporting and Data SystemInter- Intraobserver Variability in Feature Analysis Final AssessmentWendie A. Berg1 2, Cristina Campassi1, Patricia Langenberg3 Mary J. Sexton3Audio Available | Share
IX PREVIOUS SINGLE-CENTERstudies [1][2][3][4][5][6] and 3 multicenter trials 7-9 have shown supplemental screening breast ultrasound significantly increases detection of node-negative invasive cancer in women with mammographically dense tissue on the first prevalence screen, consistently increasing (yield) by 3.5 per 1000 single-center studies from 4.2 to 4.4 trials.The vast majority cancers detected only been cancers.Until now, it was See also p 1379.
To determine whether adding shear-wave (SW) elastographic features could improve accuracy of ultrasonographic (US) assessment breast masses.From September 2008 to 2010, 958 women consented repeat standard US supplemented by quantitative SW examination in this prospective multicenter institutional review board-approved, HIPAA-compliant protocol. B-mode Breast Imaging Reporting and Data System (BI-RADS) assessments were recorded. evaluation (mean, maximum, minimum elasticity stiffest portion...
To evaluate intra- and interobserver reproducibility of shear wave elastography (SWE) for breast masses.
Mammography is not widely available in all countries, and breast cancer incidence increasing. We considered performance characteristics using ultrasound (US) instead of mammography to screen for cancer.Two thousand eight hundred nine participants were enrolled at 20 sites the United States, Canada, Argentina American College Radiology Imaging 6666. Two six sixty-two completed three annual screens (7473 examinations) with US film-screen (n = 4351) or digital 3122) had biopsy 12-month...
Mammographic breast density is an established risk marker for cancer and visually assessed by radiologists in routine mammogram image reading, using four qualitative Breast Imaging Reporting Data System (BI-RADS) categories. It particularly difficult to consistently distinguish the two most common variably assigned BI-RADS categories, i.e., "scattered density" "heterogeneously dense". The aim of this work was investigate a deep learning-based classifier these aiming at providing potential...
Abstract: We sought to prospectively assess the diagnostic performance of a high-resolution positron emission tomography (PET) scanner using mild breast compression (positron mammography [PEM]). Data were collected on concomitant medical conditions potential confounding factors. At four centers, 94 consecutive women with known cancer or suspicious lesions received 18F-fluorodeoxyglucose (FDG) intravenously, followed by PEM scans. Readers provided clinical histories and x-ray mammograms (when...
To understand the pathologic basis for sonographic features of cystic lesions breast and determine appropriate assessment management recommendations these based on appearance.From a database 2,072 image-guided procedures performed from July 1995 through September 2001, 150 were identified. Diagnosis was established with fine-needle aspiration (n = 55), 14-gauge core-needle biopsy 81), or both 14). Excision all malignant 18) atypical 2) 11 benign lesions, which recurred enlarged at follow-up....
PURPOSE: To determine whether training in the Breast Imaging Reporting and Data System (BI-RADS) improves observer performance agreement with consensus of experienced breast imagers regard to mammographic feature analysis final assessment. MATERIALS AND METHODS: A test set mammograms was developed, 54 proven lesions consisting 28 masses (nine [32%] malignancies) 26 microcalcifications (10 [38%] malignancies). Three reviewed cases independently by means consensus. Twenty-three practicing...
To prospectively examine operator dependence of lesion detection, description, and interpretation when experienced breast radiologists perform whole-breast ultrasonography (US).Institutional review board approval was obtained for the HIPAA-compliant study. Ten women (aged 19-53 years; mean, 37.4 20 breasts) with numerous known lesions consented to participate. Eleven radiologists, who passed experience qualification requirements a screening US trial participate, scanned both breasts in all...
To determine the performance of positron emission mammography (PEM), as compared with magnetic resonance (MR) imaging, including effect on surgical management, in ipsilateral breasts cancer.Four hundred seventy-two women newly diagnosed breast cancer who were offered breast-conserving surgery consented from September 2006 to November 2008 participate a multicenter institutional review board-approved, HIPAA-compliant protocol. Participants underwent contrast material-enhanced MR imaging and...
To determine reasons for nonparticipation in a trial of supplemental screening with magnetic resonance (MR) imaging after mammography and ultrasonography (US).Women(n = 2809) at elevated risk breast cancer were enrolled the American College Radiology Imaging Network 6666 US Screening Protocol 21 institutions. Fourteen institutions met technical experience requirements this institutional review board-approved, HIPAA-compliant substudy MR imaging. Those women who had completed 0-, 12-,...
Abstract Purpose: False positives in digital mammography screening lead to high recall rates, resulting unnecessary medical procedures patients and health care costs. This study aimed investigate the revolutionary deep learning methods distinguish recalled but benign images from negative exams those with malignancy. Experimental Design: Deep convolutional neural network (CNN) models were constructed classify into malignant (breast cancer), cancer free), recalled-benign categories. A total of...
Purpose To investigate two deep learning‐based modeling schemes for predicting short‐term risk of developing breast cancer using prior normal screening digital mammograms in a case‐control setting. Methods We conducted retrospective Institutional Review Board‐approved study on cohort 226 patients (including 113 women diagnosed with and controls) who underwent general population screening. For each patient, (i.e., negative or benign findings) mammogram examination [including mediolateral...
Background Staging newly diagnosed breast cancer by using dynamic contrast material-enhanced MRI is limited access, high cost, and false-positive findings. The utility of contrast-enhanced mammography (CEM) 99mTc sestamibi-based molecular imaging (MBI) in this setting largely unknown. Purpose To compare extent-of-disease assessments MRI, CEM, MBI versus pathology women with cancer. Materials Methods In HIPAA-compliant prospective study, biopsy-proven underwent between October 2014 April...
Abstract Objective To determine breast radiologists’ confidence in detecting invasive lobular carcinoma (ILC) on mammography and the perceived need for additional imaging screening preoperative settings. Methods A 16-item anonymized survey was developed, IRB exemption obtained, by Society of Breast Imaging (SBI) Patient Care Delivery Committee Lobular Cancer Alliance. The emailed to 2946 radiologist SBI members February 15, 2023. recorded demographics, modality-specific sensitivity ILC...
To evaluate preoperative whole-breast ultrasonography (US) in the management of breast cancer.The ipsilateral 40 patients with known cancer or whom there was high suspicion evaluated US. Biopsy performed on all discrete solid lesions.US depicted 45 (94%) 48 invasive tumor foci and seven (44%) 16 ductal carcinoma situ (DCIS). Mammography 39 (81%) 14 (88%) DCIS. The nine (14%) 64 malignant seen only at US included three infiltrating carcinomas, two mixed intraductal lobular Two (18%) 11 were...
PURPOSE: To determine the diagnostic accuracy of ultrasonographically (US) and stereotactically guided fine-needle aspiration biopsy (FNAB) in diagnosis nonpalpable breast lesions. MATERIALS AND METHODS: At 18 institutions, 442 women who underwent 22–25-gauge imaging-guided FNAB were enrolled. Definitive surgical, core-needle biopsy, and/or follow-up information was available for 423 (95.7%) these women. The reference standard established from additional clinical imaging an six (1.4%) did...