A5057749492- Antibiotic Resistance in Bacteria
- Antibiotics Pharmacokinetics and Efficacy
- Bacterial Identification and Susceptibility Testing
- Pharmaceutical and Antibiotic Environmental Impacts
- Alzheimer's disease research and treatments
- Gastric Cancer Management and Outcomes
- Neurological disorders and treatments
- Colorectal Cancer Screening and Detection
- Diabetes Management and Education
- Neuroinflammation and Neurodegeneration Mechanisms
- Economic and Environmental Valuation
- Metabolism, Diabetes, and Cancer
- Genetic factors in colorectal cancer
- Nuclear Receptors and Signaling
- Parkinson's Disease Mechanisms and Treatments
- Analytical Methods in Pharmaceuticals
- Cancer Risks and Factors
- Forecasting Techniques and Applications
- Tryptophan and brain disorders
- Decision-Making and Behavioral Economics
- Antimicrobial agents and applications
UNSW Sydney
2025
Maastricht University
2024
Chinese University of Hong Kong
1997-2024
Heilongjiang University of Chinese Medicine
2023
Robert Gordon University
1996
Pseudomonas aeruginosa, Escherichia coli, cepacia and Moraxella catarrhalis were selected for their markedly different resistance patterns to sulphonamides trimethoprim. In addition, strains of E. coli P. having profiles the inhibition dihydropteroate synthetase dihydrofolate reductase. All inhibitors combined in any combination with reductase resulted mutual enhancement bacterial uptakes corresponding increased antibacterial activity combinations. High concentrations or p-aminobenzoic acid...
To elucidate the potential mechanisms of QFY for treatment Alzheimer's Disease (AD), and explore effective substances QFY.UPLC-LTQ-Orbitrap-MS was used to identify chemical constituents serum samples cerebrospinal fluid rats after administration. Network pharmacology predict targets pathways against AD. The AD mice model established by subcutaneous injection D-gal 8 consecutive weeks. New object recognition (NOR) Morris water maze test (MWM) were evaluate learning memory abilities mice....
AbstractAbstractA functional pharmacokinetic/pharmacodynamic (PK/PD) index that could simultaneously describe three controlling PD variables, i.e., bactericidal activity, postantibiotic effect (PAE), and susceptibility, in relation to pharmacokinetics, was designed using an vitro kinetic model. Tobramycin tested against one standard five clinical strains of Pseudomonas aeruginosa. The organisms showed minimum inhibitory concentrations (MICs) ranging between 1 >1000 μg/ml. model allowed...
The endpoints associated with conventional susceptibility testing, e.g., the minimum inhibitory concentration or bactericidal (MIC MBC), are discrete in nature. These endpoint measurements do not provide any information, regarding pharmacodynamic changes exhibited by bacteria reaction to antibiotic activity during incubation period. Another limitation of these tests is maintenance constant concentrations; this condition contrasts sharply continuously changing concentrations observed vivo. To...
The objective of this study is to evaluate the predictive ability TyG index for presence adenoma and multiple adenomas in an asymptomatic population.
In this article, we describe the mixrandregret command, which extends randregret command introduced in Gutiérrez-Vargas, Meulders, and Vandebroek (2021, Stata Journal 21: 626–658) by allowing random coefficients regret minimization models. The newly developed allows user to specify a combination of fixed function classical model Chorus (2010, European Transport Infrastructure Research 10: 181–196). addition, can normal lognormal distributions for using appropriate command’s options. models...
In vitro postantibiotic effects (PAEs) exhibited by a standard strain of Pseudomonas aeruginosa following exposure to tobramycin at constant concentrations were compared those exponentially decreasing concentrations. Exposure concentration showed more extensive bacterial killing and resulted in longer PAEs comparable areas under the concentration-time curves above MIC. This phenomenon suggests significant contribution pharmacokinetics antimicrobial pharmacodynamics.