Dentin is a vital, hydrated composite tissue with structural components and properties that vary in the different topographic portions of teeth. These variations have significant implication for biomechanical teeth adhesive systems utilized conservative dentistry. The aim this study to analyse root canal dentin going from coronal apical zone find ratio between intertubular area surface occupied by tubules varies. Observations were conducted on 30 healthy premolar extracted orthodontic...

Background/Objectives: Anterior disc displacement without reduction (ADDwoR) is a temporomandibular joint (TMJ) disorder characterized by progressive dysfunction and potential complications. Persistent leads to abnormal mechanical stress, predisposing the TMJ structural degeneration, including perforation. This case report aimed examine histological immunofluorescence characteristics of perforated tissue elucidate mechanisms contributing its pathology. Methods: A 50-year-old patient with...

Crohn's disease (CD) is a chronic intestinal inflammation considered to be major entity of inflammatory bowel diseases (IBDs), affecting different segments the whole gastrointestinal tract. Peripheral serotonin (5-HT), bioactive amine predominantly produced by gut enterochromaffin cells (ECs), crucial in functions, including motility, sensitivity, secretion, and response. These actions are mediated large family receptors specialized transporter (SERT) located on variety cell types gut....

Aim . Purpose of the present paper is to analyze efficiency different post-space irrigation protocols. Methods 28 single rooted teeth were endodontically treated. After preparation every sample was assigned one three experimental groups and control group. In each group protocols performed as follows: EDTA (Group A), 37% orthophosphoric acid B), + with ultrasounds activation C). D) irrigate association not activated by ultrasounds. Three zones (coronal, middle, apical) analyzed using Scan...

Background: Bone regeneration is a reliable technique when the bone volume insufficient to provide functional and aesthetic outcome in surgery implantoprosthesis procedures. When blocks are used but do not match shape of defect, block must be adapted. The aim our research was evaluate, by Scanning Electron Microscopy (SEM) morphological observation, how different cutting devices modify surface. Method: Four equine were divided into 15 cubic samples with ultrasonic sonic tips, as well...

Unilateral posterior crossbite is a widespread, asymmetric malocclusion characterized by an inverse relationship of the upper and lower buccal dental cusps, in molar premolar regions, on one side only arch. Patients with unilateral exhibit altered chewing cycles masseter results to be less active respect contralateral one. Few studies about morphological features masticatory muscle disorders exist most these have been performed animal models. The aim present study was evaluate protein...

Osteonecrosis of the jaw (ONJ) is an adverse effect bisphosphonate treatment that has become subject increasing investigations, in particular due to its poorly understood pathogenesis. Several experimental studies on animal models have been conducted; however, majority these replicate human ONJ following tooth extraction, and describe alterations bone gingival epithelium when necrosis manifested. The aim present study was analyze rat mandibular during 45 days zoledronate (which a agent),...

<p>Bone graft are used in dentistry for the reconstruction of severely atrophic jaws. Fresh frozen bone has no osteogenic property but it osteoconductive and osteoinductive properties because its matrix contains growth factors such as vascular endothelial factor. The purpose present study was to evaluate morphological protein expression characteristics fresh before after six months patients who needed maxillary reconstruction. After 6 month we observed presence viable evidenced by full...

The periodontal ligament (PDL) is a highly vascularized connective tissue surrounding the root of tooth. In particular, PDL continuously exposed to mechanical stresses during phases mastication, and it provides physical, sensory, trophic functions. It known that application orthodontic force creates change in structures. fact, these forces generate pressure on closes vessels. aim this study observe modifications vascular endothelial growth factor (VEGF) extracellular matrix proteins after...

The sarcoglycan complex consists of a group single-pass transmembrane glycoproteins that are essential to maintain the integrity muscle membranes. Any mutation in each gene causes series recessive autosomal dystrophin-positive muscular dystrophies. Negative fibres for sarcoglycans have never been found healthy humans and animals. In this study, we investigated whether social ranking has an influence on expression skeletal muscles baboons. Biopsies masseter sternocleidomastoid were processed...

Background: Repairing a restoration is more advantageous and less invasive alternative to its total makeover. The aim of this study was analyze the effects chemical mechanical surface treatments aimed at increasing roughness supra-nano composite resin. Methods: 27 cylindrical blocks microhybrid were made. samples randomly divided into nine groups (n = 3). samples’ treated differently per each group: acid etching (35% H3PO4, 30 s 60 s), diamond bur milling, sandblasting combination treatment...

The orthodontic tooth movement is the last step of several biological processes that take place after application external forces. During this process, dental pulp tissue subjected to structural and protein expression modifications in order maintain their integrity functional morphology. purpose present work was perform an vivo study, evaluating human patients have undergone due pre-calibrated light force for 30 days. Dental samples were extracted from molars premolars control group 7 days...

Unilateral condylar hyperplasia (UCH) is characterized by slow progression and enlargement of the condyle, accompanied elongation mandibular body, resulting in facial asymmetry, occlusal disharmony, joint dysfunction. This condition can be defined as "active" or "inactive": active form continuous growth dynamic histologic changes, whereas inactive indicates that process has stabilized. Since there are few microscopic studies on form, this study aims to investigate histological features...

A unilateral posterior crossbite is a malocclusion where the low activity of affected masseter muscle compensated by contralateral hypertrophy. It still unknown if, in same condition, myogenesis with new fibre formation takes place. Aim: aim present study was to evaluate expression markers, such as Myf5 and MyoD, muscles patients. Materials methods: biopsies from fifteen surgical patients crossbites have been analysed immunofluorescence reactions. The results show MyoD but not ipsilateral...

The use of equine bone blocks is widely reported for augmentation techniques. block must be shaped according to the form defect that should regenerated. shaping could performed by hand before or during surgery, in a sterile ambient, using CNC milling machine not sterile. aim our study was evaluate if steam sterilization provide medical grade and microstructure collagen structures change after different protocols provided mainstream autoclave.Two were divided into 16 samples. 1 sample used as...

The temporomandibular joint (TMJ) is a bilateral synovial articulation stabilized by several anatomical structures such as ligaments. existence of articular capsule reinforcement have been described in the lateral and medial sides disc which defined collateral ligaments, medial. Despite that, some macroscopic observations support that these ligaments do not belong to but they disc. By aim present work was evaluate morphological aspects TMJ from cadaveric frozen heads histological...

In invisible orthodontics, the role of composite attachments in facilitating complex tooth movements is crucial. This study, which evaluates efficacy a novel clinical attachment procedure, holds significant implications for field. The technique used two templates (one pre-drilled and other pre-loaded with high-viscosity composites) was compared standard procedure. Fifty were planned four dental arch prototypes. Dental impressions taken using digital scans virtual planning after tested...

Netherton syndrome is a severe, autosomal recessive form of ichthyosis associated with mutations in the SPINK5 gene encompassing three main clinical findings: 1) ichthyosiform dermatitis and/or linearis circumflexa, 2) hair shaft defects peculiar "trichorrhexis invaginata" (bamboo pole hair) findings, 3) atopic dermatitis. We describe two siblings affected by Netherton/Comèl who were referred to our Center for Genodermatosis. A diagnostic pathway and description new variant has been...

Unilateral posterior crossbite is a malocclusion disease that involves morpho-functional characteristics of masseter muscle; normal or increased activity contralateral muscle and reduced the ipsilateral during unilateral have been shown. Since extracellular matrix plays key role in mechano-transduction transmitting forces contraction, aim present study was to analyse behaviour this type through immunofluorescence reactions against laminin, collagen IV, MMP-2 MMP-9. Our results show an...

Bisphosphonates (BP) are stable analogues of pyrophosphate with a P-C-P structure and 2 side chains attached to the carbon atom. Intravenous bisphosphonates primarily used effective in management cancer-related conditions context solid tumors, such as breast cancer, prostate lung cancer. Moreover subministred patients metabolic bone disease osteoporosis Paget disease. Bisphosphonate-associated osteonecrosis jaws (BONJ) is really complication intravenous therapy It common knowledge that have...

Unilateral posterior crossbite is a type of malocclusion that involves morpho-functional characteristics masticatory muscle, such as the masseter: electrophysiological data have shown affected side works less than contralateral which shows normal or increased activity, probably in order to compensate for side. The aim present work was measure diameter and cross-sectional area ipsilateral muscle fibers verify if hypertrophy and/or hypotrophy take place this malocclusion. We used...

Patients with Down syndrome (DS) present delays in motor development, showing a unique pattern of locomotion clinical settings. Hippotherapy (HBR) is field rehabilitation therapy to achieve physical, social, and psychological well-being through therapeutic horse riding, providing new stimulus related gait may helping balance postural control [1], [2]. Herein, we have enrolled fifteen male individuals affected by DS, aged from 19 36 years old. All patients were vaccinated for tetanus...