A5101504951- Oral health in cancer treatment
- Peripheral Nerve Disorders
- Temporomandibular Joint Disorders
- Pharmacological Effects of Medicinal Plants
- Dental Anxiety and Anesthesia Techniques
- Head and Neck Cancer Studies
- Orthopedic Surgery and Rehabilitation
- Botulinum Toxin and Related Neurological Disorders
- Osteoarthritis Treatment and Mechanisms
- Oral Health Pathology and Treatment
- Muscle activation and electromyography studies
- Laser Applications in Dentistry and Medicine
- Motor Control and Adaptation
- Natural product bioactivities and synthesis
- Muscle Physiology and Disorders
- Advanced Numerical Analysis Techniques
- Heavy Metal Exposure and Toxicity
- Periodontal Regeneration and Treatments
- Obesity and Health Practices
- Oral and gingival health research
- Head and Neck Surgical Oncology
- Adipose Tissue and Metabolism
- Mercury impact and mitigation studies
- Psoriasis: Treatment and Pathogenesis
- Pharmacology and Obesity Treatment
University of Messina
2000-2023
Morpho (United States)
2018
Institute of Neurological Sciences
1998
Policlinico Universitario di Catania
1998
The present study evaluated the effects of low-level laser therapy (LLLT) by means a diode in accelerating orthodontic tooth movement (OTM). After extraction first upper premolars for purpose, 82 maxillary canines which needed distalization were analyzed 41 enrolled patients (21 males, 20 females, mean age 13.4 ± 2.1 years). On all experimental sites, an force 50/N was applied nickel-titanium (NiTi) closed coil spring (G&H, Franklin, IN, USA) order to obtain space closure. Using split mouth...
Human gingival fibroblasts (GF) and human oral mucosa epithelial cells (EC) with an inflammatory phenotype represent a valuable experimental paradigm to explore the curative activity of agents be used in mucositis. The role cannabinoid receptor 2 (CB2) has not yet been investigated aim this study was evaluate therapeutic potential β-Caryophyllene (BCP), CB2 agonist, vitro model GF EC were stimulated LPS (2 µg/mL) alone or combination BCP; group challenged treated BCP AM630, antagonist....
Oral mucositis is a side effect hard to treat following high dose chemotherapy or radiotherapy.Adenosine A 2A receptor stimulation blocks NF-κB and boosts the Wnt/β-catenin signaling, thus blunting inflammation triggering growth factor codifying genes.Polydeoxyribonucleotide (PDRN) registered drug that activates receptor.Therefore, aim of this study was evaluate PDRN effects in an "in vitro" model oral induced by prompting inflammatory phenotype human gingival fibroblasts (GF) mucosal...
Previous studies have demonstrated that, in addition to inducing structural changes thyroid follicles, cadmium (Cd) increased the number of C cells. We examined effects myo-inositol (MI), seleno-L-methionine (Se), MI + Se, and resveratrol on cells mice exposed chloride (Cd Cl2), as no data are currently available possible protective these molecules. In contrast, we previously shown this effect against CdCl2 follicles mice. Ninety-eight C57 BL/6J adult male were divided into 14 groups seven...
Obesity is a worldwide growing problem for the health care systems and its treatment strongly recommended. Orlistat, naltrexone/bupropion, liraglutide are approved weight loss in Italy patients with Body Mass Index (BMI) ≥ 30 kg/m2 or 27 concomitant diseases. However, prescription of these drugs significantly low worldwide. General practitioners (GPs) play key role early diagnosis appropriate management obesity. The aim study was to investigate obesity prescriptive attitude anti-obesity...
The therapeutic armamentarium for the treatment of oral mucositis is very poor. Catechin and baicalin are two natural flavonoids that have been individually reported to a curative potential. Flavocoxid mixed extract containing catechin showing antioxidant effects anti-inflammatory activity mainly due dual inhibition inducible cyclooxygenase (COX-2), 5-lipoxygenase (5-LOX) NLRP3 pathway. aim this study was evaluate anti-oxidant flavocoxid in an "in vitro" model induced by triggering...
Introduction: Drug combination is widely used to treat chronic inflammatory diseases. A similar strategy might be worth of interest design plant-derived natural products conditions. Curcumin a phenolic compound which shares anti-inflammatory activity with both flavocoxid, flavonoid mixture baicalin and catechin, β-caryophyllene, bicyclic sesquiterpene. The aim this study was investigate the synergy potential curcumin flavocoxid β-caryophyllene in human articular chondrocytes triggered...
The extracellular matrix of the articular disc in a temporomandibular joint (TMJ) is composed mainly collagen I and elastin. important for resisting tensile forces, while elastin responsible to maintain shape after deformation. We studied orientation normal human by light microscopy, immunofluorescence scanning electron microscopy. Our results demonstrated that run parallel each other intermediate zone with an anteroposterior orientation. From here, two fibers groups changes into disordered...
A patient affected by thoracic outlet syndrome, with an involvement of the left lower primary trunk due to a rudimentary cervical rib, developed severe hand dystonia on same side. The dystonic posture was characterised flexion wrist fingers curled into palm. Polygraphic recordings performed flexor digitorum superficialis (FDS4) and extensor (EDC4) muscles, during repetitive tapping task fourth digit, showed loss well formed bursts without clear silent period along long duration cocontraction...
Experimental and clinical studies have suggested that several neurological disorders are associated with the occurrence of central nervous system neuroinflammation. Metaxalone is an FDA-approved muscle relaxant has been reported to inhibit monoamine oxidase A (MAO-A). The aim this study was investigate whether metaxalone might exert antioxidant anti-inflammatory effects in HMC3 microglial cells. An inflammatory phenotype induced cells through stimulation interleukin-1β (IL-1β). Control...
<b><i>Objective:</i></b> To evaluate whether ulnar neuropathy could induce changes in spinal cord and motor cortex excitability therefore predispose to development of focal dystonia. <b><i>Background:</i></b> A high incidence has been observed patients with musician's cramp. Polygraphic electromyograph recordings entrapment the nerve at elbow have demonstrated long-duration bursts co-contraction antagonistic muscles, similar those <b><i>Methods:</i></b> All control subjects 12 underwent an...
This study evaluated the effect of low-level laser irradiation induces by diode on speed orthodontic tooth movement canines submitted to initial retraction. Twenty-four mandibular were retracted using NiTi spring (force 150 g/side). Thirteen those irradiated with a 980-nm (Wiser Laser Doctor Smile, Lambda) operating at an 810-nm wavelength (1 W output power, continuous wave 66.7 J/cm2) that was equipped 0.6-mm optical fiber in continuous-wave mode. The canine retraction accomplished...
Unilateral posterior crossbite is a malocclusion disease that involves morpho-functional characteristics of masseter muscle; normal or increased activity contralateral muscle and reduced the ipsilateral during unilateral have been shown. Since extracellular matrix plays key role in mechano-transduction transmitting forces contraction, aim present study was to analyse behaviour this type through immunofluorescence reactions against laminin, collagen IV, MMP-2 MMP-9. Our results show an...
Unilateral posterior crossbite is a type of malocclusion that involves morpho-functional characteristics masticatory muscle, such as the masseter: electrophysiological data have shown affected side works less than contralateral which shows normal or increased activity, probably in order to compensate for side. The aim present work was measure diameter and cross-sectional area ipsilateral muscle fibers verify if hypertrophy and/or hypotrophy take place this malocclusion. We used...
The dystrophin-glycoprotein complex is a multimeric system made up of the sarcoglycan sub-complex, sarcomplasmatic and dystroglycans complex. sub-complex stabilizes sarcolemma during muscle activity plays role in force transduction. This protein also expressed non-human primates such as chimpanzees baboons, its expression changes depending on social ranking. In fact, previous data have shown that all fibers masseter sternocleidomastoid muscles high- ranking baboons always express...