A5101538566- Glaucoma and retinal disorders
- Visual perception and processing mechanisms
- Retinal Development and Disorders
- Vestibular and auditory disorders
- Advanced Neuroimaging Techniques and Applications
- Photoreceptor and optogenetics research
- Ophthalmology and Visual Impairment Studies
- Functional Brain Connectivity Studies
- Retinal and Optic Conditions
- Ocular and Laser Science Research
- Ophthalmology and Eye Disorders
Second Affiliated Hospital of Nanchang University
2018-2025
Nanchang University
2015-2025
First Affiliated Hospital of Nanchang University
2017
Sun Yat-sen University
2001
Purpose Using voxel-wise degree centrality (DC), as measured by resting-state fMRI, we aimed to study alterations in the brain functional networks patients with primary angle-closure glaucoma (PACG) and reveal plastic trajectories of surgery. Methods A total 23 preoperative PACG (49.48 ± 14.37 years old) were recruited undergo a fMRI scan, 9 them rescanned 3 months after All underwent complete ophthalmologic examination, including intraocular pressure (IOP), retinal nerve fiber layer (RNFL)...
Objective: In this study, we aimed to investigate the frequency-dependent spontaneous neural activity in primary angle-closure glaucoma (PACG) using amplitude of low-frequency fluctuations (ALFF) method. Patients and methods: total, 52 PACG individuals (24 males 28 females) normal-sighted controls (NS; 24 who were closely matched age, sex, education underwent resting-state magnetic resonance imaging scans. A repeated-measures ANOVA post hoc two-sample t -tests conducted analyze different...
Purpose To investigate the altered intrinsic functional connectivity (iFC) of primary visual cortex (V1) in angle-closure glaucoma (PACG) patients before and after surgery using resting-state MRI. Materials Methods Twenty-five preoperative PACG (pre-PACG) 25 well-matched healthy controls (HCs) were included this study, 9 assessed again at least 3 months treatment (post-PACG). We generated iFC maps seed regions centers left right V1 conducted group comparisons. Then, relationships between...
The study aimed to compare the whole-brain gray matter volume (GMV) and white (WMV) difference between primary angle closure glaucoma (PACG) patients health controls (HCs) using a voxel-based morphometry method. A total of 27 with PACG (17 males 10 females) HCs females), closely matched for age education, were enrolled in study. All subjects underwent magnetic resonance imaging (MRI) scans. MRI data processed SPM8 software 8 toolbox. relationship mean GMV values brain regions clinical...
Background Previous neuroimaging studies demonstrated that primary angle closure glaucoma patients were associated with abnormal intrinsic brain activity in visual cortex (V1). Purpose The purpose of this study was to investigate the effective connectivity patterns V1 glaucoma. Material and Methods Thirty-seven (20 men, 17 women) 36 healthy controls 16 closely matched for age, sex, education, underwent resting-state MRI scans. A voxel-wise Granger causality analysis method performed explore...
Background Previous neuroimaging studies demonstrated that patients with primary angle-closure glaucoma were accompanied by abnormal neuronal activity. Purpose To investigate frequency-dependent local oscillations synchronization in using the regional homogeneity method. Material and Methods In total, 37 individuals (20 men, 17 women) normal-sighted controls closely matched age, sex, education underwent resting-state MRI scans. We compared different values full band (0.01–0.08 Hz) two...