Lucas José Sá da Fonseca

ORCID: 0000-0002-8850-841X
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About
Contact & Profiles
Research Areas
  • Nitric Oxide and Endothelin Effects
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Systemic Lupus Erythematosus Research
  • Cardiovascular Health and Disease Prevention
  • Biochemical effects in animals
  • Vasculitis and related conditions
  • Inflammatory Myopathies and Dermatomyositis
  • Cardiac Ischemia and Reperfusion
  • Muscle and Compartmental Disorders
  • Systemic Sclerosis and Related Diseases
  • Drug-Induced Hepatotoxicity and Protection
  • Rheumatoid Arthritis Research and Therapies
  • Heart Rate Variability and Autonomic Control
  • Urticaria and Related Conditions
  • Botulinum Toxin and Related Neurological Disorders
  • Psoriasis: Treatment and Pathogenesis
  • Mosquito-borne diseases and control
  • Ear Surgery and Otitis Media
  • Cancer Diagnosis and Treatment
  • Spondyloarthritis Studies and Treatments
  • Innovative Teaching Methods
  • Thermoregulation and physiological responses
  • Biomedical and Engineering Education
  • Vitamin K Research Studies
  • Advanced Glycation End Products research

Universidade Federal de Alagoas
2010-2019

Universidade Federal de Minas Gerais
2019

National Institute of Science and Technology
2016

Universidade Estadual Paulista (Unesp)
2013

Faculdade de Medicina do ABC
2013

Universidade Federal de São Paulo
2013

This study evaluated the oxidative stress through enzymatic and nonenzymatic biomarkers in diabetic patients with without hypertension prediabetics. The SOD CAT (in erythrocytes) GPx plasma) activities, plasma levels of lipid peroxidation, total thiols were measured blood 55 subjects type 2 diabetes 38 (9 pre-diabetics 29 controls) aged 40–86 years. activity peroxidation higher diabetics compared to nondiabetics. In stratified groups, was different for hypertensive prediabetics normotensive...

10.1155/2012/819310 article EN cc-by Oxidative Medicine and Cellular Longevity 2012-01-01

Nonalcoholic fatty liver disease (NAFLD) has been considered a novel component of the metabolic syndrome (MetS), with oxidative stress participating in its progression. This study aimed to evaluate profile young and old mice MetS, effects apocynin tempol on glycemic lipid parameters. Young C57BL/6 high fat diet- (HFD-) induced MetS received 50 mg·kg(-1)/day their drinking water for 10 weeks. After HFD, group showed elevated fasting glucose, worsened plasma, steatosis, hepatic peroxidation....

10.1155/2016/1987960 article EN cc-by Oxidative Medicine and Cellular Longevity 2016-01-01

Teaching physiology, a complex and constantly evolving subject, is not simple task. A considerable body of knowledge about cognitive processes teaching learning methods has accumulated over the years, helping teachers to determine most efficient way teach, highlighting student's active participation as means improve outcomes. In this context, paper describes qualitatively analyzes an experience student-centered teaching-learning methodology based on construction physiological-physical...

10.1186/1472-6920-14-189 article EN cc-by BMC Medical Education 2014-09-15

The present study evaluated the cardiometabolic and redox balance profiles in patients with Metabolic Syndrome compared to apparently healthy individuals, participation of myeloperoxidase/hydrogen peroxide axis systemic lipid peroxidation. Twenty-four eighteen controls underwent a full clinical assessment. Venous blood samples were collected for general biochemical dosages, as well oxidative stress analyses (superoxide dismutase, catalase, arginase activities; peroxidation, myeloperoxidase...

10.1155/2014/898501 article EN cc-by Oxidative Medicine and Cellular Longevity 2014-01-01

Vários estudos destacam as espécies reativas de oxigênio e nitrogênio (ERONs) como importantes contribuintes na patogênese numerosas doenças cardiovasculares, incluindo hipertensão, aterosclerose falência cardíaca. Tais são moléculas altamente bioativas com vida curta derivadas, principalmente, da redução do molecular. O complexo enzimático NADPH oxidase é a maior fonte dessas vasculatura. Sob condições fisiológicas, formação eliminação destas substâncias aparecem balanceadas parede...

10.1590/s0066-782x2010000500018 article PT cc-by-nc Arquivos Brasileiros de Cardiologia 2010-05-01

Since antiquity, the human arterial pulse represents an important parameter in clinical assessment. Besides being routinely assessed medical practice, such is not observed its completeness yet, once many of data obtained through it cannot be evaluated using conventional methods. Taking into account methods, measurement blood pressure sphygmomanometry, although broadly widespread assessment and follow-up patients who require accompaniment their cardiovascular status, able to properly guide...

10.4236/wjcd.2014.45030 article EN World Journal of Cardiovascular Diseases 2014-01-01

6th year medical student - Federal University of Alagoas.Universidade de Alagoas (UFAL).Send correspondence to: Av. Alvaro Otacilio, 3031 apto. 402. Ponta Verde, Maceio AL. CEP: 57035-180.Paper submitted to the BJORL-SGP (Publishing Management System – Brazilian Journal Otorhinolaryngology) on August 08, 2010; and accepted October 12, 2010. cod. 7261

10.1590/s1808-86942011000500026 article EN cc-by Brazilian Journal of Otorhinolaryngology 2011-10-01

This manuscript reports a case of intestinal toxemia botulism in an adult with recently diagnosed metastatic colon cancer whom symptoms began 23 days after hospital admission. Representing the rarest form presentation clinical practice, this infectious disease may have developed due to cluster predisposing factors that favored Clostridium botulinum colonization and endogenous production neurotoxins, among which are previous use broad-spectrum antibiotics changes related development...

10.1590/s1678-9946201961049 article EN Revista do Instituto de Medicina Tropical de São Paulo 2019-01-01
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