A5072381167- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Streptococcal Infections and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Cardiac Imaging and Diagnostics
- Inflammasome and immune disorders
- Tuberculosis Research and Epidemiology
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Aortic Disease and Treatment Approaches
- Congenital Heart Disease Studies
- Cardiovascular Issues in Pregnancy
- Immunodeficiency and Autoimmune Disorders
- Viral Infections and Immunology Research
- Hematological disorders and diagnostics
- Heart Failure Treatment and Management
- Pulmonary Hypertension Research and Treatments
- Hepatitis B Virus Studies
- Public Health in Brazil
- Systemic Lupus Erythematosus Research
- Pharmacological Effects of Natural Compounds
- Mycobacterium research and diagnosis
Universidade de São Paulo
2014-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2005-2024
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2024
Instituto do Coração
2008-2021
Hospital São Paulo
2021
Hospital do Coração
2003-2021
Interamerican Society of Cardiology
2020
Sociedade Brasileira de Cardiologia
2020
Valve (United States)
2003-2016
Universidade Federal do Acre
2015
Background— Although the Cox-Maze III procedure is effective for treating permanent atrial fibrillation (AF), its high complexity limits use. The Saline-Irrigated Cooled-tip Radiofrequency Ablation (SICTRA) System an alternative source of energy used to ablate AF. aim this study was evaluate effectiveness SICTRA treatment AF in patients with rheumatic mitral valve (MV) disease. Methods and Results— Between February 2002 April 2003, 70 MV disease were randomly assigned undergo a modified Maze...
1. Introduction There are currently a wide modalities of interventional strategies – both transcatheter and surgical which can be indicated for patients with valvular heart diseases (VHD), the objective reducing morbidity mortality. The correct timing indication type treatment linked to precise anatomical functional diagnosis VHD, comprehensive global evaluation patient. 2020 Update Brazilian Guidelines in addition compiling [...]
N-Acetylglucosamine (GlcNAc) is the major immunoepitope of group A streptococcal cell wall carbohydrates. Antistreptococcal antibodies cross-reactive with anti-GlcNAc and laminin are present in sera patients rheumatic fever. The cross-reactivity these human heart valvular endothelium underlying basement membrane has been suggested to be a possible cause immune-mediated valve lesion. Mannose-binding lectin (MBL) encoded by MBL2 gene, soluble pathogen recognition receptor, high affinity for...
Autoimmune inflammatory reactions leading to rheumatic fever (RF) and heart disease (RHD) result from untreated Streptococcus pyogenes throat infections in individuals who exhibit genetic susceptibility. Immune effector mechanisms have been described that lead tissue damage culminating mitral aortic valve dysfunctions. In myxomatous degeneration (MXD), the is also damaged due non-inflammatory mechanisms. Both diseases are characterized by structural disarray a previous proteomic analysis of...
Objective: Rheumatic fever (RF) and the antiphospholipid syndrome (APS) are autoimmune diseases that share similar cardiac neurological pathologies. We assessed presence of shared epitopes between M protein, N-acetyl-β-d-glucosamine (GlcNAc) β2 glycoprotein-I (β2GPI), pathogenic molecules engaged in these conditions.
Introducao A indicacao da intervencao cirurgica ou percutânea no paciente com doenca valvar esta atrelada ao preciso diagnostico anatomico e funcional, alem do conhecimento historia natural doenca. Nesta atualizacao Diretriz Brasileira de Valvopatias 2011, sao contemplados apenas pacientes valvopatia anatomicamente importante (estagios C D American College of Cardiology (ACC)/ Heart Association (AHA), 2014). As tabelas fluxogramas que aqui constam demonstram passos sequenciais norteiam o...
SUMMARY Introduction: the EuroSCORE II and STS are most used scores for surgical risk stratification indication of transcatheter aortic valve implantation (TAVI). However, its role as a tool mortality prediction in patients undergoing TAVI is still unclear. Objective: to evaluate performance predictors in-hospital 30-day TAVI. Methods: we included 59 symptomatic with severe stenosis that underwent between 2010 2014. The variables were analyzed using Student's t-test Fisher's exact test...
Rheumatic heart disease (RHD) affects heart-valve tissue and is the most serious consequence of group A Streptococcus infection. Myxomatous degeneration (MXD) frequent valvopathy in western world. In present work, key protein expression alterations RHD MXD patients were identified characterized, with controls from cadaveric organ donors. Proteins separated by two-dimensional (2D)-electrophoresis mass spectrometry. We found 17 differentially expressed spots, as compared to control samples....
By comparing 51 heart disease patients with history of rheumatic fever and 46 no history, the authors found a higher prevalence obsessive-compulsive symptoms in subjects. This suggests that activity is not necessary condition for expression neuropsychiatric symptoms.
Rheumatic fever (RF) remains endemic in many countries and frequently causes heart failure due to severe chronic rheumatic valvular disease, which requires surgical treatment. Here, we report on a patient who underwent an elective correction for mitral aortic disease had post-operative diagnosis of acute carditis. The incidental finding Aschoff bodies myocardial biopsies is reported the nineteenth-century literature, with prevalences as high 35%, but no clinical or prognostic data patients...
Epidemiological differences can be found between Brazilian and European valvular heart disease patients. The prevalence of valve diseases due to rheumatic is significantly higher in the compared with population. Therefore, they could have different risks during after cardiac surgery. aim this study was evaluate applicability additive logistic EuroSCORE II a cohort high-risk patients predominantly aetiology submitted surgery.Between 1 February 30 December 2009, 540 consecutive scheduled for...
Abstract Background Corynebacterium diphtheriae ( C. ) infections, usually related to upper airways involvement, could be highly invasive. Especially in developing countries, non-toxigenic strains are now emerging as cause of invasive disease like endocarditis. The present case stands out for reinforcing the high virulence this pathogen, demonstrated by multiple systemic embolism and severe valve deterioration. It also emphasizes importance a coordinated interdisciplinary work address all...
FUNDAMENTO: A coronariografia tem sido indicada no pré-operatório para valvopatas >35 anos. Entretanto, a real prevalência de doença arterial coronariana (DAC) obstrutiva nessa população pouco estudada. OBJETIVO: Avaliar e os fatores risco DAC em candidatos cirurgia valvar Brasil. MÉTODOS: Foi realizada angiocoronariografia 3.736 pacientes avaliados associada valvopatia. RESULTADOS: esteve valvopatia 121 (prevalência 3,42%). Em 79 (68,1%), o diagnóstico foi feito apenas por pré-operatória....