A5079809471- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Optical Coherence Tomography Applications
- Peripheral Artery Disease Management
- Cardiac pacing and defibrillation studies
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Cardiovascular Function and Risk Factors
- Aortic Disease and Treatment Approaches
- Cardiac Ischemia and Reperfusion
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Acute Myocardial Infarction Research
- Thermal Regulation in Medicine
- Pericarditis and Cardiac Tamponade
- Cardiac tumors and thrombi
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Artery Anomalies
- Cardiovascular and Diving-Related Complications
- Trauma Management and Diagnosis
University Hospitals of Cleveland
2019-2025
Case Western Reserve University
2019-2024
University School
2022-2024
Pulmonary Vascular Research Institute
2023
Valve (United States)
2019-2022
Universidade de São Paulo
2010-2022
Cleveland Heights University Heights Public Library
2022
Instituto do Coração
2019-2021
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2017-2021
Sociedade Brasileira de Cardiologia
2021
1. Epidemiologia da Parada Cardiorrespiratoria e Apresentacao Diretriz […] Atualizacao de Ressuscitacao Cardiopulmonar Cuidados Cardiovasculares Emergencia Sociedade Brasileira Cardiologia – 2019
Diretrizes da Sociedade Brasileira de Cardiologia sobre Angina Instavel e Infarto Agudo do Miocardio sem Supradesnivel Segmento ST – 2021
For intravascular OCT (IVOCT) images, we developed an automated atherosclerotic plaque characterization method that used a hybrid learning approach, which combined deep-learning convolutional and hand-crafted, lumen morphological features. Processing was done on innate A-line units with labels fibrolipidic (fibrous tissue followed by lipidous tissue), fibrocalcific calcification), or other. We trained/tested expansive data set (6,556 images), performed active learning, relabeling step to...
We developed a fully automated, two-step deep learning approach for characterizing coronary calcified plaque in intravascular optical coherence tomography (IVOCT) images. First, major calcification lesions were detected from an entire pullback using 3D convolutional neural network (CNN). Second, SegNet model with the Tversky loss function was used to segment plaques lesions. The connected conditional random field and frame interpolation of missing frames reduce classification errors....
Left atrial appendage occlusion (LAAO) has emerged as an alternative to anticoagulation for reducing stroke risk in patients with fibrillation (AF). However, heart failure (HF) may have enhanced of and elevated this procedure. To further investigate population, the authors present a retrospective analysis on LAAO HF. The performed review all hospitalizations using National Readmissions Database between September 2015 November 2019. From these, ICD-10 codes HF were identified. Propensity...
Compared with other imaging modalities, intravascular optical coherence tomography (IVOCT) has significant advantages for guiding percutaneous coronary interventions, assessing their outcomes, and characterizing plaque components. To aid IVOCT research studies, we developed the Optical Coherence TOmography PlaqUe Stent (OCTOPUS) analysis software, which provides highly automated, comprehensive of plaques stents in images.User specifications OCTOPUS were obtained from detailed, iterative...
Patients who undergo permanent pacemaker (PPM) implantation after transcatheter aortic valve replacement (TAVR) have a worse outcome. The aim of this study was to identify risk factors outcomes in patients with post-TAVR PPM implantation.This is single-centre, retrospective consecutive underwent from 11 March 2011 9 November 2019. Clinical were evaluated by landmark analysis cut-off at 1 year the implantation. Of 1389 TAVR during duration and total 110 included final analysis. Right...
Percutaneous left atrial appendage occlusion (LAAO) with the Watchman device is FDA approved for stroke prevention in patients nonvalvular fibrillation who have an appropriate indication. During COVID-19 pandemic, a same-day discharge protocol (SDDP) was employed to improve resource utilization, relieve hospital occupation, and reduce possible risk of in-hospital virus transmission.
Abstract It can be difficult/impossible to fully expand a coronary artery stent in heavily calcified lesion. Under-expanded stents are linked later complications. Here we used machine/deep learning analyze calcifications pre-stent intravascular optical coherence tomography (IVOCT) images and predicted the success of vessel expansion. Pre- post-stent IVOCT image data were obtained from 110 lesions. Lumen segmented using deep learning, lesion features extracted. We analyzed expansion along...
Abstract In this work, a strain-based degradation model was implemented and validated to better understand the dynamic interactions between bioresorbable vascular scaffold (BVS) artery during process. Integrating strain-modulated equation into commercial finite element codes allows control visualization of local mechanical parameters. Both strut thinning discontinuity stent struts within an were captured visualized. The predicted results in terms mass loss fracture locations by documented...
Use of intracoronary imaging is associated with improved outcomes in patients undergoing percutaneous coronary intervention (PCI). Yet, the impact on real-time physician decision-making during PCI not fully known.The LightLab Initiative a multicenter, prospective, observational study designed to characterize use standardized optical coherence tomography (OCT) workflow PCI. Participating physicians performed pre-PCI and post-PCI OCT accordance this operator assessments lesion characteristics...
Thin-cap fibroatheroma (TCFA) and plaque rupture have been recognized as the most frequent risk factor for thrombosis acute coronary syndrome. Intravascular optical coherence tomography (IVOCT) can identify TCFA assess cap thickness, which provides an opportunity to vulnerability. We developed automated method that detect lipidous fibrous thickness in IVOCT images. This study analyzed a total of 4360 image frames 77 lesions among 41 patients. Expert cardiologists manually labeled based on...
Microvessels in vascular plaque are associated with progression and found rupture intra-plaque hemorrhage. To analyze this characteristic of vulnerability, we developed an automated deep learning method for detecting microvessels intravascular optical coherence tomography (IVOCT) images. A total 8403 IVOCT image frames from 85 lesions 37 normal segments were analyzed. Manual annotation was performed using a dedicated software (OCTOPUS) previously by our group. Data augmentation the polar...
While there is recent data suggesting an advantage of computed tomography angiography (CTA) over transesophageal echocardiography (TEE) for preprocedural left atrial appendage closure (LAAC) planning, limited published experience sizing strategies. Device LAAC may be challenging and noninvasive algorithms that improve this selection process are warranted.We sought to evaluate the safety feasibility implementation a novel CTA-based methodology WATCHMAN™ FLX device in series patients...
Abstract Thin-cap fibroatheroma (TCFA) is a prominent risk factor for plaque rupture. Intravascular optical coherence tomography (IVOCT) enables identification of fibrous cap (FC), measurement FC thicknesses, and assessment vulnerability. We developed fully-automated deep learning method segmentation. This study included 32,531 images across 227 pullbacks from two registries (TRANSFORM-OCT UHCMC). Images were semi-automatically labeled using our OCTOPUS with expert editing established...
Abstract Background Transcatheter aortic valve replacement (TAVR) has become an established method of stenosis treatment but suffers from the risk heart block and pacemaker requirement. Risk stratification for patients who may develop remains imperfect. Simultaneously, myocardial fibrosis as measured by cardiac magnetic resonance imaging (CMR) been demonstrated a prognostic indicator ventricular recovery mortality following TAVR. However, association CMR‐based measures with post‐TAVR...
The MANTA vascular closure device (VCD) represents a novel approach to achieving hemostasis after large-bore femoral access procedures. Numerous clinical studies have evaluated the efficacy of across range patient populations undergoing different However, there is still paucity data available concerning use devices in aiding decannulation venoarterial extracorporeal membrane oxygenation (VA-ECMO).