A5014890553- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Public Health in Brazil
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Healthcare Regulation
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Lipoproteins and Cardiovascular Health
- Atrial Fibrillation Management and Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiac and Coronary Surgery Techniques
- Heart Failure Treatment and Management
- Diet and metabolism studies
- Adipokines, Inflammation, and Metabolic Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Atherosclerosis and Cardiovascular Diseases
- Blood Pressure and Hypertension Studies
- Cardiac Arrest and Resuscitation
- Youth, Drugs, and Violence
- Healthcare during COVID-19 Pandemic
- Cardiac pacing and defibrillation studies
- Vitamin C and Antioxidants Research
- Microscopic Colitis
Pontifícia Universidade Católica do Rio Grande do Sul
2015-2024
Hospital São Lucas da PUCRS
2009-2023
Vifor Pharma (Switzerland)
2020
Hospital Universitário Clementino Fraga Filho
2018
Universidade de São Paulo
2018
Universidade Federal de Sergipe
2018
Fundación Cardiovascular de Colombia
2017
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2017
Sociedade Brasileira de Cardiologia
2002-2016
Duke Medical Center
2016
The aim of this study is to compare spironolactone versus clonidine as the fourth drug in patients with resistant hypertension a multicenter, randomized trial. Medical therapy adherence was checked by pill counting. Patients (no office and ambulatory blood pressure [BP] monitoring control, despite treatment 3 drugs, including diuretic, for 12 weeks) were an additional 12-week (12.5–50 mg QD) or (0.1–0.3 BID). primary end point BP control during (<140/90 mm Hg) 24-h (<130/80 monitoring....
Diretrizes da Sociedade Brasileira de Cardiologia sobre Angina Instavel e Infarto Agudo do Miocardio sem Supradesnivel Segmento ST – 2021
<h3>Importance</h3> Inflammation promotes cardiovascular disease and anti-inflammatory treatment reduces events in patients with chronic coronary syndrome. Chronic kidney (CKD) is a risk factor for disease. It unclear how inflammation mediated by interleukin 6 (IL-6) CKD linked to <h3>Objective</h3> To investigate associations between IL-6 outcomes syndrome association function. <h3>Design, Setting, Participants</h3> This multicenter cohort study included enrolled at 663 centers 39 countries...
Chagas' disease is an important cause of cardiomyopathy in Latin America. We aimed to compare clinical characteristics and outcomes patients with heart failure (HF) reduced ejection fraction caused by disease, other etiologies, the era modern HF therapies.This study included 2552 American randomized PARADIGM-HF (Prospective Comparison ARNI With ACEI Determine Impact on Global Mortality Morbidity Heart Failure) ATMOSPHERE (Aliskiren Trial Minimize Outcomes Patients trials. The...
AimsPre-clinical and few clinical studies suggest that transplantation of autologous bone marrow mononuclear cells (BMNC) improves heart function in dilated cardiomyopathies. Our objective was to determine if intracoronary injection BMNC the left ventricular ejection fraction (LVEF) patients with non-ischaemic cardiomyopathy (NIDCM).
Abstract Context: Metabolic syndrome (MS) is described as a cluster of cardiometabolic risk factors. Studies suggest that ischemia-modified albumin (IMA) biomarker cardiovascular diseases. IMA levels could be associated with risks and represent possible indication microvascular dysfunction in MS patients. Objective: To confirm this association, we evaluated the association between MS. Design: We performed case-control study (32 healthy individuals 74 subjects MS) to evaluate MS, IMA, other...
Objective . The main goal of the present study was to investigate xanthine oxidase (XO) activity in metabolic syndrome subjects submitted a single exercise session. We also investigated parameters oxidative and inflammatory status. Materials/Methods A case-control (9 healthy 8 MS volunteers) performed measure XO, superoxide dismutase (SOD), glutathione peroxidase activities, lipid peroxidation, high-sensitivity C-reactive protein (hsCRP) content, glucose levels, profile. Body mass indices,...
The objective of the Aliskiren Trial on Acute Heart Failure Outcomes (ASTRONAUT) was to determine whether aliskiren, a direct renin inhibitor, would improve post-discharge outcomes in patients with hospitalization for heart failure (HHF) reduced ejection fraction. Pre-specified subgroup analyses suggested potential heterogeneity aliskiren and without baseline diabetes mellitus (DM).ASTRONAUT included 953 DM (aliskiren 489; placebo 464) 662 319; 343) (as reported by study investigators)....
Background: Lifestyle intervention programs can reduce the prevalence of metabolic syndrome (MetS) and, therefore, risk for cardiac disease, one main public health problems nowadays. Objective: The aim this study was to compare effects three types approach lifestyle change in reduction parameters, and identify its impact on quality life (QOL) individuals with MetS. Methods: A randomized controlled trial included 72 MetS aged 30-59 years. Individuals were into groups multidisciplinary...
Despite all progress made in understanding and treating systemic arterial hypertension (SAH), the study of impact psychological disorders SAH is still controversial not well understood. Our aim was to test hypothesis that can be associated with anxiety depressive symptoms verify its effect on quality life.A controlled cross-sectional included 302 patients (152 hypertensive 150 normotensive) outpatients at Hospital São Lucas PUC-RS. Measurements were individual interviews data collection...
Purpose To estimate the effect size of a serious game for cardiopulmonary resuscitation (CPR) training in comparison with video-based on-line course terms learning outcomes among medical students before simulation-based CPR using manikin. Methods Participants were 45 first-year randomly assigned to self-training either Apple Keynote presentation (n = 22) or developed 3D environment 23) up 20 min. Each participant was evaluated on written, multiple-choice test (theoretical test) and then...
The mediastinitis is a serious postoperative complication of cardiac surgery, with an incidence 0.4 to 5% and mortality between 14 47%. Several models were proposed assess risk after surgery. However, most these do not evaluate the morbidity.This study aims develop score model predict for patients undergoing coronary artery bypass grafting.The sample included data from 2,809 adult grafting January 1996 December 2007 at Hospital São Lucas -PUCRS. Logistic regression was used examine...
OBJETIVOS: Analisar o impacto da hemotransfusão sanguínea na incidência de desfechos clínicos no pós-operatório (PO) cirurgias cardíacas. MÉTODOS: Estudo coorte retrospectiva. Foram analisados 4.028 pacientes submetidos à cirurgia revascularização miocárdica (CRM), troca valvar (TV) ou ambas, em hospital terciário universitário brasileiro, entre 1996 e 2009. comparadas as complicações PO os hemotransfundidos (n=916) não-hemotransfundidos (n=3112). Foi realizada análise univariada através do...
A síndrome metabólica é um transtorno complexo representado por conjunto de fatores risco cardiovascular.A adoção estilo vida saudável está fortemente relacionada à melhora da Qualidade Vida e interfere forma positiva no controle dos presentes nessa condição clínica.Objetivo: Avaliar o efeito programa modificação do
It now appears that obesity is associated with a low-grade inflammation of white adipose tissue resulting from chronic activation the innate immune system as interleukin-1 beta (IL-1). Previous investigations have described positive association between IL-1 +3953 (C>T) gene polymorphism (rs 1143634) and obesity, suggesting functional effects on fat mass, metabolism body mass. However, it necessary to determine if these results occur in other populations they are influenced by sex age....
Objective: To determine the risk factors related to development of stroke in patients undergoing cardiac surgery.Methods: A historical cohort study.We included 4626 aged ≥ 18 years who underwent coronary artery bypass surgery, heart valve replacement surgery alone or combined with grafting between January 1996 and December 2011.The relationship predictors was assessed by logistic regression model a significance level 0.05.Results: The incidence 3% overall sample.After regression, following...
FUNDAMENTO: Estabelecer escore de risco para cirurgias cardíacas permite avaliar pré-operatório, informar o paciente e definir cuidados durante a intervenção. OBJETIVO: Pesquisar fatores pré-operatórios óbito em cirurgia cardíaca valvar construir um modelo simples (escore) mortalidade hospitalar os pacientes candidatos à no Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande Sul (HSL-PUCRS). MÉTODOS: A amostra estudo inclui 1.086 adultos que realizaram entre Janeiro 1996...