- Reproductive Physiology in Livestock
- Birth, Development, and Health
- Parathyroid Disorders and Treatments
- Reproductive Biology and Fertility
- Forensic and Genetic Research
- Genetic and phenotypic traits in livestock
- Growth Hormone and Insulin-like Growth Factors
- Reproductive System and Pregnancy
- Ovarian function and disorders
- Forensic Anthropology and Bioarchaeology Studies
- Magnesium in Health and Disease
- Estrogen and related hormone effects
- Archaeology and ancient environmental studies
- Adipose Tissue and Metabolism
- Genetic Syndromes and Imprinting
- Circadian rhythm and melatonin
- Genetic diversity and population structure
- Heavy Metal Exposure and Toxicity
- Race, Genetics, and Society
- Arsenic contamination and mitigation
- Dermatological and Skeletal Disorders
- Climate change impacts on agriculture
- Cultural Industries and Urban Development
- Effects of Environmental Stressors on Livestock
- Crop Yield and Soil Fertility
Universidad de Zaragoza
2015-2024
Swedish University of Agricultural Sciences
2015
Bridgepoint (United Kingdom)
2013
Hospital Universitario Miguel Servet
2006-2012
Zero to Three
2011
Observatorio Astronómico Los Molinos
2003-2009
Universidad de Montevideo
2004
National University of Salta
1970
Consejo Nacional de Investigaciones Científicas y Técnicas
1970
Whereas efficient and sensitive nanoheaters nanothermometers are demanding tools in modern bio- nanomedicine, joining both features a single nanoparticle still remains real challenge, despite the recent progress achieved, most of it within last year. Here we demonstrate successful realization this challenge. The heating is magnetically induced, temperature readout optical, ratiometric thermometric probes dual-emissive Eu3+/Tb3+ lanthanide complexes. low thermometer heat capacitance...
The objective of the Aliskiren Trial on Acute Heart Failure Outcomes (ASTRONAUT) was to determine whether aliskiren, a direct renin inhibitor, would improve post-discharge outcomes in patients with hospitalization for heart failure (HHF) reduced ejection fraction. Pre-specified subgroup analyses suggested potential heterogeneity aliskiren and without baseline diabetes mellitus (DM).ASTRONAUT included 953 DM (aliskiren 489; placebo 464) 662 319; 343) (as reported by study investigators)....
CR Climate Research Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsSpecials 65:53-69 (2015) - DOI: https://doi.org/10.3354/cr01326 Contribution Special: 'Modelling climate change impacts for food security' Variability of effects spatial data aggregation on regional yield simulation by crop models H. Hoffmann1,*, G. Zhao1; L. J. van Bussel1,2, A. Enders1, X. Specka3, C. Sosa4, Yeluripati5, 16, F. Tao6,...
ABSTRACT Ancient molecular typing depends on DNA survival in archaeological bones. Finding valuable tools to predict presence ancient samples, which can be measured prior undertaking a genetic study, has become an important issue as consequence of the peculiarities samples. Since is explained by complex interrelations multiple variables, aim present study was analyze morphological, structural, chemical, and biological aspects set medieval human bones, provide accurate reflection state...
CR Climate Research Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsSpecials 65:141-157 (2015) - DOI: https://doi.org/10.3354/cr01301 Contribution Special: 'Modelling climate change impacts for food security' Effect of weather data aggregation on regional crop simulation different crops, production conditions, and response variables Gang Zhao1,*, Holger Hoffmann1, Lenny G. J. van Bussel1,2, Andreas...
In the present study, it was investigated whether undernutrition affected binding capacity, immunoreactivity and mRNA expression for uterine oestrogen progesterone receptors (ER PR, respectively) in sheep, as well responses were associated with changes plasma concentrations of (P4), oestradiol (E2), glucose, fatty acids, insulin, leptin insulin-like growth factor (IGF)-I during oestrous cycle. Twenty ewes fed either 1.5 (C) or 0.5 (L) times their maintenance requirements killed on Day 5 14...
Before the arrival of Spaniards in Nicaragua, diverse Native American groups inhabited territory. In colonial times, Nicaraguan populations interacted with Europeans and slaves from Africa. To ascertain extent this genetic admixture provide evidence about origin ancestors, we analyzed mitochondrial control region (HVSI HVSII), 17 Y chromosome STRs, 15 autosomal STRs 165 Mestizo individuals Nicaragua. carry out interpopulation comparisons, HVSI sequences 29 were compiled literature. The...
Beef cows and ewes grazing native pastures are exposed to cycles of undernutrition that reflect the seasonal variations biomass production. In dairy cows, physiological during early lactation due increased demands for low dry matter intake is exacerbated by need get sufficient from pasture extra energy costs. Undernutrition has profound impacts on reproduction affecting multiple reproductive processes at different levels axis. The objective this paper review influence events adult female...
Melatonin plays a crucial role in enhancing reproductive performance small ruminants. This paper reveals the effects of exogenous melatonin on placental and endometrial rearrangement early pregnancy sheep.
Background Vascular calcification (VC) is primarily studied using cultures of vascular smooth muscle cells. However, the use very different protocols and extreme conditions can provide findings unrelated to VC. In this work we aimed determine critical experimental parameters that affect in vitro relevance vivo. Experimental Procedures Results Rat VSMC was concentrations fetal calf serum, calcium, phosphate, types culture media, various volumes rates change. The bicarbonate content media...
This study evaluated the effects of exogenous melatonin and level nutrition on oocyte competence, in vitro fertilization (IVF), early embryonic development sheep during seasonal anoestrus (SA) reproductive season (RS). Adult Rasa Aragonesa ewes were assigned randomly to one four treatment groups two experiments based a 2 × factorial design. Individuals treated (+MEL) or not (−MEL) with subcutaneous implant for 42 days then fed 1.5 (Control, C) 0.5 (Low, L) times daily maintenance...
Several mechanisms have been proposed to explain the vascular toxicity of arsenic. Some them are described in this work, such as stress-induced premature senescence (SIPS), dedifferentiation, and medial calcification, they all affect smooth muscle cells (VSMC). Rat aortic VSMC were treated with 1-100 µM either sodium arsenate (As(V)), arsenite (As(III)), monomethylarsonic acid, or dimethylarsinic acid. None treatments induced calcification presence 1mM inorganic phosphate (Pi), but 1 As(III)...
To determine the effect of undernutrition on embryo production and quality in superovulated sheep, 45 ewes were allocated into two groups to be fed diets that provided 1.5 (control, C; n = 20) or 0.5 (low nutrition, L; 25) times daily requirements for maintenance, from oestrous synchronization with intravaginal sponges collection. Embryos collected 7 days after onset oestrus (day 0). Low nutrition resulted lower live weight body condition at collection (P < 0.05). Diet 0.01) day sampling...
The effects of pregnancy and undernutrition on endometrial gene expression were investigated in ewes fed all or half their maintenance requirements killed Day 14 the oestrous cycle. progesterone, oestrogen, oxytocin interferon receptors (PR, ERα, OXTR IFNAR, respectively), cyclo-oxygenase (COX)-2, proliferating cell nuclear antigen (PCNA), insulin-like growth factors (IGF)-I -II, IGF-1 receptor (IGF-1R) was studied by immunohistochemistry real-time reverse transcription–polymerase chain...
Maternal periconceptional undernutrition is associated with altered development and increased risks of adverse outcomes in the offspring. This circumstance normal flocks under extensive farming systems, which depend on natural forage resources. The aim this study was to determine effect sheep behavioral reproductive aspects Eighty ewes were synchronized estrus allocated two groups ( n =40) be fed diets that provided 1.5 (C) or 0.5 (L) times requirements for maintenance. Ewes mated 7 days...
Because of the adverse effects that diagenesis exert on ancient skeletal remains, DNA from these samples is often compromised to point where genetic typing can be challenging. Nevertheless, robust and reliable methods are currently available allow successful genotyping specimens. Here we report nuclear DNA–based strategies used analyze 2 human skeletons a medieval burial. Reliable profiles were obtained teeth, whereas mitochondrial analyses in bones inconclusive. A complete mini short tandem...
Summary This study investigated whether a 22‐day period of undernutrition (half maintenance) could affect maternal endocrine responses and liver gene expression during early pregnancy (day 7). Thirty‐five ewes were fed 1.5 ( n = 15) or 0.5 20) their maintenance requirements slaughtered on day 7 the oestrus cycle (oestrus 0). Insulin, IGF, leptin non‐esterified fatty acids (NEFA) determined days −14, 0 7. Transcripts IGF family adipokines receptors in by real‐time RT‐PCR. Underfed animals...