A5055276776- 3D Printing in Biomedical Research
- Mechanical Behavior of Composites
- Carbon Nanotubes in Composites
- Microfluidic and Bio-sensing Technologies
- Smart Materials for Construction
- Numerical methods in engineering
- Gold and Silver Nanoparticles Synthesis and Applications
- Spectroscopy Techniques in Biomedical and Chemical Research
- Biosensors and Analytical Detection
- Fatigue and fracture mechanics
- Advanced Sensor and Energy Harvesting Materials
- Conflict of Laws and Jurisdiction
- Neuroscience and Neural Engineering
- Nanopore and Nanochannel Transport Studies
- Higher Education and Teaching Methods
- Cancer Cells and Metastasis
- Cellular Mechanics and Interactions
- Epoxy Resin Curing Processes
- Microfluidic and Capillary Electrophoresis Applications
- Advanced biosensing and bioanalysis techniques
- European and International Contract Law
- Law, logistics, and international trade
- Plant Water Relations and Carbon Dynamics
- Composite Material Mechanics
- Electrocatalysts for Energy Conversion
Chengdu Women's and Children's Central Hospital
2024-2025
University of Electronic Science and Technology of China
2024-2025
Tianjin University
2023-2025
Virginia Tech
2014-2024
University of Notre Dame
2020-2024
State Grid Corporation of China (China)
2024
Dalian Medical University
2024
University of Jinan
2023-2024
Shaanxi Normal University
2021-2023
North China Electric Power University
2023
Surface-enhanced Raman spectroscopy (SERS) has emerged as an ultrasensitive molecular-fingerprint-based technique for label-free biochemical analysis of biological systems. However, conventional SERS substrates, enhancement factors (EFs) strongly depend on background refractive index (RI), which prevents reliable spatiotemporal living cells consisting different extra-/intracellular organelles with a heterogeneous distribution local RI values between 1.30 and 1.60. Here, we demonstrate that...
Abstract Hyaluronic acid (HA) is a high‐value biopolymer used in the biomedical, pharmaceutical, cosmetic, and food industries. Current methods of HA production, including extraction from animal sources streptococcal cultivations, are associated with high costs health risks. Accordingly, development bioprocesses for production centered on robust “Generally Recognized as Safe (GRAS)” organisms such Bacillus subtilis highly attractive. Here, we report novel strains B. which membrane...
A microfluidic device composed of variable numbers multiconstriction channels is reported in this paper to differentiate a human breast cancer cell line, MDA-MB-231, and nontumorigenic MCF-10A. Differences between their mechanical properties were assessed by comparing the effect single or multiple relaxations on velocity profiles which novel measure deformation ability. Videos cells recorded via microscope using smartphone, imported tracking software gain position information cells. Our...
Plasmonic nanostructure-enabled label-free surface-enhanced Raman spectroscopy (SERS) emerges as a rapid nondestructive molecular fingerprint characterization technique for complex biological samples. However, SERS bioanalysis faces challenges in reliability and reproducibility due to signals' high susceptibility local optical field variations at plasmonic hotspots, which can bias correlations between the measured spectroscopic features actual concentration profiles of biochemical matrices....
Current biomarkers for myocardial infarction (MI) diagnosis are typically late markers released upon cell death, incapable of distinguishing between ischemic and reperfusion injury can be symptoms other pathologies. Circulating microRNAs (miRNAs) have recently been proposed as alternative MI diagnosis; however, detecting the changes in human cardiac miRNA profile during is extremely difficult. Here, to study levels acute MI, a heart-on-chip model with channel, containing induced pluripotent...
Rapid in situ bio-analysis of cellular behaviors response to external stimuli remains a formidable challenge but can open crucial opportunities biology and medicine. The standard label-based end point assays suffer from invasiveness complex sample handling. In this regard, label-free surface-enhanced Raman spectroscopy (SERS) has emerged as promising non-invasive technique for living cells. Nevertheless, achieving rapid SERS still faces challenges reliable high-throughput measurements...
Recently, direct inkjet printing of conductive solutions has received much attention in the microfluidics and lab-on-a-chip community because its low-cost mask-free deposition electrodes on various substrates. However, investigation micro-scale polydimethylsiloxane (PDMS) substrate not been completed. Here we present a technique to produce narrow (40–90 µm) silver microelectrodes PDMS. Extensive experimental characterization studies pattern uniformity electrical properties printed lines are...
It has been observed that carbon nanotubes have a measurable inherent piezoresistive effect, is to say changes in nanotube strain can induce resistivity, which may lead observable macroscale response of nanotube–polymer nanocomposites. In this article, the focus on modeling effect piezoresistivity nanocomposite’s behavior using computational micromechanics techniques based finite element analysis. Both in-plane and axial responses are being considered an electromechanically coupled code. The...
The macroscale piezoresistive response, i.e. the change in electrical resistivity under application of strain, carbon nanotube–polymer nanocomposites has been observed to lead gauge factors which are much larger than commonly used strain gauges. Whereas most gauges rely on geometric effects, result a combination nanoscale mechanisms, namely tunneling (electron hopping) and nanotube inherent piezoresistivity, can substantial differences between nanocomposite at zero an applied strain. This...
In uniaxial tension and compression experiments, carbon nanotube (CNT)-polymer nanocomposites have demonstrated exceptional mechanical coupled electrostatic properties in the form of piezoresistivity. order to better understand correlation piezoresistive response with CNT dispersion at mesoscale, a 3D computational multiscale micromechanics model based on finite element analysis is constructed predict effective macroscale CNT/polymer nanocomposites. The key factors that may contribute...
With the rapid development of economy and society, trend deep integration new generation big data technology talent cultivation in vocational colleges is becoming increasingly evident. This article takes multimodal transport composite talents as an example, proposing construction a mechanism for industry education based on platforms, creating school enterprise collaborative model guided by analysis, establishing "one-stop" internship training base developing multi-level wide-ranging...
Sorting particles or cells of specific sizes in complex systems has long been a focus many researchers. Acoustic surface waves, which generate acoustic radiation forces on and, thus, influence their motion, are commonly used for the non-destructive separation sizes. In previous studies, frequency wave generation limited by interdigitated transducer (IDT). To extend effective operating range IDT, slanted-finger (SFIT) with wide path and multiple frequencies was designed. Compared traditional...
Circulating tumor cells (CTCs) are broadly accepted as an indicator for early cancer diagnosis and disease severity. However, there is currently no reliable method available to capture enumerate all CTCs most systems require either initial CTC isolation or antibody-based enumeration. Many size-based detection microfluidic platforms have been presented in the past few years. Here we describe a new size-based, multiple-row cell entrapment device that captured LNCaP-C4-2 prostate with >95%...