Objective This study aimed to investigate the association of daily branched‐chain amino acid (BCAA) intake with risks obesity and insulin resistance in children mothers gestational diabetes mellitus (GDM). Methods Daily BCAA was calculated by using a validated food frequency questionnaire 996 GDM. The odds ratios (ORs) (95% CI) childhood were obtained logistic regression models. Results multivariable‐adjusted ORs for overweight increased across quartiles ( P < 0.05 trend)....

This study aimed to assess the associations between clinical characteristics and chronic complications in latent autoimmune diabetes adults (LADA) type 2 diabetes.This is a retrospective study. Our registry included 6975 patients aged 30-75 years old with phenotypic who underwent islet autoantibody screening 2003 2012; 384 were identified have LADA. Rates of for LADA compared using 1 : matched design. Logistic models fitted identify presence diabetic including gender, age, duration diabetes,...

Aim . To investigate the association between serum magnesium levels and microvascular complications among patients with diabetes. Methods Patients diabetes were recruited April 2012 January 2015. All received an assay of concentration, screened for 24 h albumin excretion rate, underwent nonmydriatic fundus photography. Albuminuria retinopathy defined accordingly. A total 3,100 normal included in this study. Results albuminuria and/or had lower than without these (<mml:math...

Osteopontin (OPN) is one kind of cytokine which can play a number roles in promoting activation T lymphocyte, regulating balance between Th1 and Th2, participating cell-induced immunologic response stimulating B lymphocyte to express multi-clone antibodies. Some researches have showed that OPN may be involved the pathogenesis systemic lupus erythematosus (SLE). The aim this study was investigate possible association single nucleotide polymorphism (SNP) at position 9250 exon 7 gene (OPN 9250)...

This study aimed to compare pancreatic volume and its clinical significance among patients with type 2 diabetes mellitus (DM), adult-onset 1 DM latent autoimmune in adults (LADA).This is a cross-sectional study. One hundred twenty-six outpatients (68 LADA 58 DM) 158 inpatients (71 87 non-diabetic controls) were recruited during May-July 2013 Shanghai Jiao Tong University Affiliated Sixth People's Hospital. All the underwent abdominal computerized tomography; was then calculated.The mean...

To explore the influence of glycemic levels on serum carcinoembryonic antigen (CEA) in patients with diabetes.This is a cross-sectional study. Patients diabetes aged 18-75 years old were recruited. Those carcinoma, abnormal renal function (serum creatinine ≥ 115 μmol/l), and hepatic alanine aminotransferase 97.5 U/l) excluded this Blood samples obtained from every patient after an overnight fasting, CEA was determined using chemiluminescent particle immunoassay.A total 324 type 1 3019 2...

To examine pancreatic volume (PV) changes among patients with different duration of type 2 diabetes and whether atrophy was associated loss insulin secretory capacity.This cross-sectional study (203 diabetes, 93 controls without diabetes) conducted from January 2016 to December 2017. Patients were divided into 3 groups: recently diagnosed (duration ≤ years), midterm 3-9 long term ≥ 10 years). All the scanned upper abdominal computerized tomography; PV then calculated by an experienced...

Aims. To explore the relationship between monocyte-to-HDL cholesterol ratio (MHR) and endothelial function in patients with type 2 diabetes (T2DM). Methods. 243 diagnosed T2DM were enrolled this cross-sectional study. Patients divided into two groups by flow-mediated dilation (FMD) quintile as nonendothelial dysfunction ( <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1"><mtext>FMD</mtext><mo>≥</mo><mn>6.4</mn><mi>%</mi></math> )...

Twins, due to their unique genetic and environmental relationships, have provided crucial insight in our understanding of contributions numerous etiologically complex disorders developed countries. As the leading cause death adult disability, cardio- cerebrovascular diseases are common China, followed by cancer. Obesity psychological increasing. The overall goal this program is develop a resource for epidemiologic studies these other China. Our initial focus delineate determinants vascular...

To explore the relationship between serum growth differentiation factor 15 (GDF15) and metabolic abnormalities in Chinese pregnant women.We recruited 200 patients with gestational diabetes mellitus (GDM) 211 matched normal control within 24-28 weeks of pregnancy. Enzyme-linked immunosorbent assay (ELISA) was used to determine GDF15 levels all participants. Then we grouped participants according number (including blood glucose, lipids pressure), divided them into a group, one abnormality two...

Branched-chain amino acid (BCAA) has been reported to be associated with obesity, the association of BCAA visceral fat area (VFA) and subcutaneous (SFA) remained unclear in patients type 2 diabetes. This cross-sectional study was conducted 284 diabetes mellitus. Enzyme-linked immunospecific assay used measure levels serum branched-chain keto (BCKA). VFA SFA were measured bio-impedance analysis method. The between calculated using Pearson correlation multivariable linear regression analysis....

<title>Abstract</title> Background Branched-chain amino acid (BCAA) has been reported to be associated with obesity, the association of BCAA visceral fat area (VFA) and subcutaneous (SFA) remained unclear in patients type 2 diabetes. Methods This cross-sectional study was conducted 284 diabetes mellitus. Enzyme-linked immunospecific assay used measure levels seral branched-chain keto (BCKA). VFA SFA were measured bioimpedance analysis method. The between obtained using Pearson correlation...

Objective To evaluate the functional and radiological outcomes of supramalleolar osteotomy (SMOT) with fibular for mid-staged varus ankle arthritis. Methods From April 2009 to 2014, data twenty-two patients osteoarthritis who were treated SMOT combined followed up at least one yearwere retrospectively analyzed. There 5 males 17 females mean age 52.4 years (range, 37-71 years). According modified Takakura stage, there cases in stage II, 12 IIIa IIIb. The American orthopedic foot...

Objective To investigate the relationship between BMI and lower extremity arterial disease (LEAD) in T2DM patients. Methods 1592 hospitalized patients with were recruited from Endocrinology Department of Sixth Affiliated Hospital Shanghai Jiao Tong University. All classified into 4 groups according to BMI: emaciation group (BMI<18.5) , normal (18.5≤BMI<25) overweight (25≤BMI<30) obesity (BMI≥30) . Color Doppler ultrasound examination was carried out all pa-tients. And they judged as...

目的 探讨核苷(酸)类似物(NAs)经治复发的慢性乙型肝炎(CHB)患者采用恩替卡韦(ETV)单药治疗或ETV联合阿德福韦酯(ADV)治疗的临床疗效。 方法 采用前瞻性、观察性研究方法，连续收集2016年1月1日至8月31日在衢州市人民医院感染科治疗的NAs经治复发的CHB患者69例，随机分为ETV组(n＝34)和ETV＋ADV组(n＝35)治疗96周，观察治疗过程中两组患者丙氨酸转氨酶(ALT)复常率、HBeAg血清学转换率和HBV DNA阴转率。采用SPSS 19.0软件对数据进行分析。 结果 在96周的随访中，ETV组5例失访，29例完成随访；ETV＋ADV组1例患者出现范可尼综合征，停用ADV，单用ETV治疗，34例完成随访。治疗48周，ETV＋ADV组的ALT复常率和HBV DNA阴转率均高于ETV组(88.2%比65.5%，90.1%比69.0%，χ2＝4.673和5.007，P值均<0.05)。治疗96周，ETV＋ADV组的ALT复常率、HBeAg血清学转换率和HBV...