A5100776646- Kawasaki Disease and Coronary Complications
- Coronary Interventions and Diagnostics
- Coronary Artery Anomalies
- Cardiac Imaging and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Lymphoma Diagnosis and Treatment
- Orthopaedic implants and arthroplasty
- Neonatal and fetal brain pathology
- Esophageal and GI Pathology
- Reconstructive Surgery and Microvascular Techniques
- Esophageal Cancer Research and Treatment
- Cardiovascular Issues in Pregnancy
- Mechanical Circulatory Support Devices
- Total Knee Arthroplasty Outcomes
- Glioma Diagnosis and Treatment
- Tissue Engineering and Regenerative Medicine
- Cardiac Structural Anomalies and Repair
- Salivary Gland Disorders and Functions
- Oral microbiology and periodontitis research
- Antiplatelet Therapy and Cardiovascular Diseases
- Orthopedic Infections and Treatments
- Nerve Injury and Rehabilitation
- Medical Research and Treatments
- Psoriasis: Treatment and Pathogenesis
- CNS Lymphoma Diagnosis and Treatment
Guangzhou Medical University
2015-2024
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2024
Guangxi Medical University
2024
Tianjin Children's Hospital
2020-2024
Guangzhou Institute of Dermatology
2012-2024
Wenzhou Medical University
2024
First Affiliated Hospital of Guangzhou Medical University
2020-2024
First Affiliated Hospital of GuangXi Medical University
2024
Henan Provincial People's Hospital
2023
Zhengzhou University
2023
Background: While factors affecting the course of knee osteoarthritis are mostly unknown, lesions on bone scan and mechanical malalignment increase risk for radiographic deterioration. Bone marrow edema magnetic resonance imaging correspond to lesions. Objective: To determine whether in subarticular patients with identify knees at high progression these associated limb malalignment. Design: Natural history study. Setting: A Veterans Administration hospital Boston, Massachusetts. Patients:...
Platinum-based chemotherapy is the standard first-line treatment for advanced esophageal squamous cell carcinoma (ESCC). In this phase 3 study (ClinicalTrial.gov: NCT03829969), 514 patients with treatment-naïve ESCC were randomized (1:1) to receive toripalimab or placebo in combination paclitaxel plus cisplatin (TP) every weeks up 6 cycles, followed by maintenance. At prespecified final analysis of progression-free survival (PFS), a significant improvement PFS observed arm over (hazard ratio...
Anomalous coronary arteries are a rare but recognized cause of myocardial ischemia and sudden death. Identification currently requires x-ray angiography, which may have difficulty defining the three-dimensional course anomalous vessel. Magnetic resonance angiography (MRCA) has been shown to image artery anatomy noninvasively. We hypothesize that MRCA be useful in identification their anatomic course.Sixteen patients (9 men, 7 women, age 44 81 years) with aortic origins by conventional...
Background: Coronavirus disease 2019 (COVID-19) has been a global pandemic disease, with more than 4 million cases and nearly 300,000 deaths. Little is known about COVID-19 in patients chronic obstructive pulmonary (COPD). We aimed to evaluate the influence of preexisting COPD on progress outcomes COVID-19. Methods: This was multicenter, retrospective, observational study. enrolled 1,048 aged 40 years above, including 50 998 without COPD, confirmed via high-throughput sequencing or real-time...
Abstract Background Accumulating evidence shows that mesenchymal stem cells (MSCs) have the potential as a cellular therapy avenue for schistosome-induced liver injury. Extracellular vesicles (EVs) are membranous released by almost all cell types, and EVs produced MSCs (MSC-EVs) exert therapeutic effects in several disease models. However, of MSC-EVs schistosomiasis treatment remains unclear. Methods Using survival analysis, HE Masson’s trichrome staining, immunohistochemical, western blot...
Only few comparative studies have been reported on the outcomes of minimally invasive esophagectomy (MIE) with intrathoracic anastomosis (MIE Ivor-Lewis) and MIE cervical McKeown) for patients mid lower esophageal cancer. The objective this study is to compare safety, feasibility, short-term between two groups.Clinical surgical data cancer who underwent either Ivor-Lewis or McKeown January 2013 October 2014 were retrospectively analyzed. Demographic characteristics, pathological data,...
Background A low glycemic index (GI) diet is beneficial for glucose control in patients with diabetes mellitus. This study aimed to investigate the influence of a low-GI on postprandial levels women gestational mellitus (GDM). Methods Pregnant GDM were randomized receive normal diabetic or staple 5 days. food was used replace rice lunch and dinner group, whereas total energy carbohydrate remained equal both groups. Fasting determined daily. Results 140 pregnant included study, including 66...
Hepatocyte transplantation has been proposed as an effective treatment for patients with acute liver failure (ALF), but its application is limited by a severe shortage of donor livers. Human pluripotent stem cells (hPSCs) have emerged potential cell source regenerative medicine. amniotic epithelial (hAESCs) derived from membrane multilineage differentiation which makes them suitable possible in hepatocyte regeneration and ALF treatment. The characteristics, immunogenicity, tumorigenicity...
Objective This study aimed to investigate the association of daily branched‐chain amino acid (BCAA) intake with risks obesity and insulin resistance in children mothers gestational diabetes mellitus (GDM). Methods Daily BCAA was calculated by using a validated food frequency questionnaire 996 GDM. The odds ratios (ORs) (95% CI) childhood were obtained logistic regression models. Results multivariable‐adjusted ORs for overweight increased across quartiles ( P < 0.05 trend)....
Our study aims to compare ultrasound (US)-guided percutaneous microwave ablation (PMWA) and conventional thyroidectomy in benign thyroid nodules (BTN) treatment.From December 2015 2017, a total of 280 patients with at least one nodule were studied retrospectively, including 156 treated US-guided PMWA 124 thyroidectomy. Propensity score matching was performed decrease the confounding bias due retrospective assignment balance pre-operation data two groups. A 106 pairs (1:1) created. The...
Abstract Objectives To report the clinical outcomes of RESTORE drug‐coated balloon (DCB; Cardionovum, Bonn, Germany) for treatment de novo small vessel disease (SVD) beyond 1 year. Background Previous reports have demonstrated noninferiority DCB to RESOLUTE Integrity drug‐eluting stent (DES; Medtronic, Minneapolis, Minnesota) in terms 9‐month in‐segment percent diameter stenosis. Methods In prospective, multicenter, SVD China trial, 230 patients with visually‐estimated reference (RVD) ≥2.25...
Background Primary central nervous system lymphoma (PCNSL) is a highly aggressive and rare extranodal non-Hodgkin (NHL). The MSKCC the IELSG scores represent most widely used prognostic models, but many changes have occurred in therapeutic protocols since their development. Moreover, PCNSL patients cannot be classified using score. We thus aimed to create novel, effective feasible model for PCNSL. Methods included 248 diagnosed with Our primary endpoint was overall survival (OS) we receiver...
Abstract Objective Belimumab has been demonstrated efficient in improving the clinical outcome of patients with lupus nephritis (LN). However, evidence regarding its efficacy and safety LN nephrotic syndrome (NS) remains limited. Methods This retrospective study included 23 (10 NS) treated belimumab for 18 months. The renal response including complete (CRR), partial (PRR) primary (PERR) at month 18, outcomes were assessed based on 2024 KDIGO guideline. Results Following additional treatment...
As a key element in the T-helper 17 (Th17) cell-mediated inflammatory process, interleukin-23 receptor (IL-23R) may play crucial role pathogenesis of atherosclerosis. Single nucleotide polymorphisms (SNPs) IL-23R have been studied several diseases. However, its association with coronary artery disease (CAD) remains unclear. This study examined whether genetic were associated susceptibility to CAD. Two SNPs, rs1884444 and rs6682925, genotyped 462 CAD patients 486 healthy controls. Data showed...
Objective Tortuosity of the carotid artery is a common angiographic finding that may impact blood flow and neuronal function. However, information on its prevalence risk factors remains limited. In this study, we determined to explore affecting tortuosity. Methods The head neck computed tomography angiography (CTA) imaging cerebral data performed at Second Affiliated Hospital Wenzhou Medical University between January 2019 September 2021 were collected, total 356 cases enrolled in study...
Background— Numerous studies have compared the outcomes of coronary artery bypass grafting (CABG) surgery and stenting for treatment multivessel disease. In 2003, drug-eluting stents were introduced with hope reducing restenosis. However, limited information exists on comparison CABG surgery. The long-term outcome that is also unclear. Methods Results— We identified 3720 consecutive patients disease who underwent isolated or received between April 1, 2004, December 31, 2005, we safety (total...
<i>Background:</i> Whether hypercholesterolemia is a risk factor for contrast-induced acute kidney injury (CI-AKI) remains unclear. In the present study, effects of short- and long-term dietary on contrast media-induced nephrotoxicity were evaluated. <i>Methods:</i> Rats fed either normal rodent diet (N) or high-cholesterol (H). At end 2 8 weeks, rats from each group given tail vein injection iohexol (group NC HC) vehicle N H). Blood lipids, renal function...