A5101884650- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Peripheral Neuropathies and Disorders
- Animal Genetics and Reproduction
- Axon Guidance and Neuronal Signaling
- Viral Infectious Diseases and Gene Expression in Insects
- Immunodeficiency and Autoimmune Disorders
- Virus-based gene therapy research
- Immunotherapy and Immune Responses
- Multiple Sclerosis Research Studies
- Cancer Immunotherapy and Biomarkers
Third Affiliated Hospital of Sun Yat-sen University
2008-2018
Sun Yat-sen University
2008-2018
Atherosclerosis, a multifactorial chronic disease, is the main cause of death and impairment in world. Endothelial cells (ECs) apoptosis plays crucial role onset development atherosclerosis, whereas underlying molecular mechanisms are unclear. MicroRNA-142-3p (miR-142-3p) well-defined tumor suppressor several types cancer, while miR-142-3p ECs atherosclerosis has yet to be elucidated. Therefore, present study aimed investigate during mechanism.Human aortic endothelial (HAECs) were treated...
Objective To construct an adenoviral vector carrying the gene encoding ciliary neurotrophic factor (CNTF). Methods The fragment CNTF was amplified from pMEG-CNTF plasmid by PCR and Psp-CNTF-IRES-GFP PDC316-CNTF-IRES-GFP plasmids were constructed. Using PBHG plasmids, Ad-CNTF-IRES-GFP constructed, constructed amplified, purified identified in 293-LP cells. Ectopic overexpression of induced using human bone marrow-derived mesenchymal stem cells (MSCs) to investigate role promoting...